Gene detail

Detailed information of KXJ11195.1 in Exaiptasia diaphana

Genomic Location: LJWW01000377.1:108971...114485
NR annotation: XP_020905893.1, methyl-CpG-binding domain protein 3 [Exaiptasia diaphana]

Gene Structure

Sequence

Uniprot

Gene family

Uniprot term	Description
Q9Z2D8	Methyl-CpG-binding domain protein 3 OS=Mus musculus OX=10090 GN=Mbd3 PE=1 SV=1
O95983	Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1
Q9UBB5	Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1

Gene family	Subfamily
Transcription Factors Family	MBD

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF14048	MBD_C	C-terminal domain of methyl-CpG binding protein 2 and 3	Family	Interproscan
PF16564	MBDa	p55-binding region of Methyl-CpG-binding domain proteins MBD	Domain	Interproscan
PF01429	MBD	Methyl-CpG binding domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001739	Domain	Methyl-CpG DNA binding	Interproscan
IPR025884	Domain	Methyl-CpG binding protein 2/3, C-terminal domain	Interproscan
IPR016177	Homologous_superfamily	DNA-binding domain superfamily	Interproscan
IPR032343	Domain	Methyl-CpG-binding domain protein 2/3, p55-binding region	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12396	METHYL-CPG BINDING PROTEIN, MBD	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0003677	Molecular Function	DNA binding	Interproscan
GO:0000122	Biological Process	negative regulation of transcription by RNA polymerase II	Interproscan
GO:0005634	Cellular Component	nucleus	Interproscan
GO:0006346	Biological Process	DNA methylation-dependent constitutive heterochromatin formation	Interproscan
GO:0008327	Molecular Function	methyl-CpG binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K11590	MBD2; methyl-CpG-binding domain protein 2	-	Chromosome and associated proteins	ko03036	deepkoala