Genomic Location: LJWW01000144.1:370226...373575
NR annotation: KXJ18797.1, Volume-regulated anion channel subunit LRRC8A [Exaiptasia diaphana]
| CDS | ||||
| KXJ18797.1 | ||||
| Transcript |
| - |
| Protein |
| KXJ18797.1 |
| Uniprot term | Description |
|---|---|
| Q68F79 | Volume-regulated anion channel subunit LRRC8E OS=Xenopus tropicalis OX=8364 GN=lrrc8e PE=2 SV=1 |
| Q6NU09 | Volume-regulated anion channel subunit LRRC8E OS=Xenopus laevis OX=8355 GN=lrrc8e PE=2 SV=1 |
| Q5DU41 | Volume-regulated anion channel subunit LRRC8B OS=Mus musculus OX=10090 GN=Lrrc8b PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13855 | LRR_8 | Leucine rich repeat | Repeat | Interproscan |
| PF00656 | Peptidase_C14 | Caspase domain | Domain | Interproscan |
| PF12534 | Pannexin_like | Pannexin-like TM region of LRRC8 | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002138 | Domain | Peptidase C14, caspase non-catalytic subunit p10 | Interproscan |
| IPR029030 | Homologous_superfamily | Caspase-like domain superfamily | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR011600 | Domain | Peptidase C14, caspase domain | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR021040 | Domain | LRRC8, pannexin-like TM region | Interproscan |
| IPR015917 | Domain | Peptidase C14A, caspase catalytic domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR47901 | CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004197 | Molecular Function | cysteine-type endopeptidase activity | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0050727 | Biological Process | regulation of inflammatory response | Interproscan |
| GO:0072557 | Cellular Component | IPAF inflammasome complex | Interproscan |
| GO:0072559 | Cellular Component | NLRP3 inflammasome complex | Interproscan |
| GO:0097169 | Cellular Component | AIM2 inflammasome complex | Interproscan |
| GO:0008234 | Molecular Function | cysteine-type peptidase activity | Interproscan |