Genomic Location: LJWW01000099.1:450423...468624
NR annotation: KXJ21223.1, Pre-mRNA-processing-splicing factor 8 [Exaiptasia diaphana]
| CDS | ||||
| KXJ21223.1 | ||||
| Transcript |
| - |
| Protein |
| KXJ21223.1 |
| Uniprot term | Description | |||
|---|---|---|---|---|
| Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2 | |||
| Q99PV0 | Pre-mRNA-processing-splicing factor 8 OS=Mus musculus OX=10090 GN=Prpf8 PE=1 SV=2 | |||
| P34369 | Pre-mRNA-splicing factor 8 homolog OS=Caenorhabditis elegans OX=6239 GN=prp-8 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|Beta-prp |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|CDC20 |
| Ubiquitin Family | E3|E3 adaptor Cullin RING|DWD |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08082 | PRO8NT | PRO8NT (NUC069), PrP8 N-terminal domain | Domain | Interproscan |
| PF08083 | PROCN | PROCN (NUC071) domain | Domain | Interproscan |
| PF10597 | U5_2-snRNA_bdg | U5-snRNA binding site 2 of PrP8 | Domain | Interproscan |
| PF10598 | RRM_4 | RNA recognition motif of the spliceosomal PrP8 | Domain | Interproscan |
| PF00400 | WD40 | WD domain, G-beta repeat | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR019775 | Conserved_site | WD40 repeat, conserved site | Interproscan |
| IPR012591 | Domain | PRO8NT domain | Interproscan |
| IPR027652 | Family | Pre-mRNA-processing-splicing factor 8 | Interproscan |
| IPR012592 | Domain | PROCN domain | Interproscan |
| IPR037190 | Homologous_superfamily | LIS1, N-terminal | Interproscan |
| IPR001680 | Repeat | WD40 repeat | Interproscan |
| IPR012337 | Homologous_superfamily | Ribonuclease H-like superfamily | Interproscan |
| IPR006594 | Conserved_site | LIS1 homology motif | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| IPR019581 | Domain | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding | Interproscan |
| IPR019582 | Domain | RNA recognition motif, spliceosomal PrP8 | Interproscan |
| IPR042516 | Homologous_superfamily | Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11140 | PRE-MRNA SPLICING FACTOR PRP8 | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0000398 | Biological Process | mRNA splicing, via spliceosome | Interproscan |
| GO:0000244 | Biological Process | spliceosomal tri-snRNP complex assembly | Interproscan |
| GO:0005681 | Cellular Component | spliceosomal complex | Interproscan |
| GO:0005682 | Cellular Component | U5 snRNP | Interproscan |
| GO:0017070 | Molecular Function | U6 snRNA binding | Interproscan |
| GO:0030619 | Molecular Function | U1 snRNA binding | Interproscan |
| GO:0030620 | Molecular Function | U2 snRNA binding | Interproscan |
| GO:0030623 | Molecular Function | U5 snRNA binding | Interproscan |
| GO:0071013 | Cellular Component | catalytic step 2 spliceosome | Interproscan |
| GO:0097157 | Molecular Function | pre-mRNA intronic binding | Interproscan |
| GO:0003723 | Molecular Function | RNA binding | Interproscan |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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