Gene detail

Detailed information of KXJ22535.1 in Exaiptasia diaphana

Genomic Location: LJWW01000079.1:227294...245426
NR annotation: KXJ22535.1, Prolyl 4-hydroxylase subunit alpha-1 [Exaiptasia diaphana]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q1RMU3	Prolyl 4-hydroxylase subunit alpha-1 OS=Bos taurus OX=9913 GN=P4HA1 PE=1 SV=1
P13674	Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2
Q5RAG8	Prolyl 4-hydroxylase subunit alpha-1 OS=Pongo abelii OX=9601 GN=P4HA1 PE=2 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01287	eIF-5a	Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold	Domain	Interproscan
PF13640	2OG-FeII_Oxy_3	2OG-Fe(II) oxygenase superfamily	Domain	Interproscan
PF21485	IF5A-like_N	Translation initiation factor 5A-like, N-terminal	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR012340	Homologous_superfamily	Nucleic acid-binding, OB-fold	Interproscan
IPR005123	Domain	Oxoglutarate/iron-dependent dioxygenase	Interproscan
IPR045054	Family	Prolyl 4-hydroxylase	Interproscan
IPR020189	Domain	Translation elongation factor, IF5A C-terminal	Interproscan
IPR011990	Homologous_superfamily	Tetratricopeptide-like helical domain superfamily	Interproscan
IPR008991	Homologous_superfamily	Translation protein SH3-like domain superfamily	Interproscan
IPR001884	Family	Translation elongation factor IF5A-like	Interproscan
IPR019769	PTM	Translation elongation factor, IF5A, hypusine site	Interproscan
IPR006620	Domain	Prolyl 4-hydroxylase, alpha subunit	Interproscan
IPR044862	Domain	Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain	Interproscan
IPR014722	Homologous_superfamily	Large ribosomal subunit protein uL2, domain 2	Interproscan
IPR048670	Domain	Translation initiation factor 5A-like, N-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10869	PROLYL 4-HYDROXYLASE ALPHA SUBUNIT	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004656	Molecular Function	procollagen-proline 4-dioxygenase activity	Interproscan
GO:0005783	Cellular Component	endoplasmic reticulum	Interproscan
GO:0018401	Biological Process	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Interproscan
GO:0003723	Molecular Function	RNA binding	Interproscan
GO:0003746	Molecular Function	translation elongation factor activity	Interproscan
GO:0043022	Molecular Function	ribosome binding	Interproscan
GO:0045901	Biological Process	positive regulation of translational elongation	Interproscan
GO:0045905	Biological Process	positive regulation of translational termination	Interproscan
GO:0005515	Molecular Function	protein binding	Interproscan
GO:0005506	Molecular Function	iron ion binding	Interproscan
GO:0016705	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Interproscan
GO:0031418	Molecular Function	L-ascorbic acid binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K00472	P4HA; prolyl 4-hydroxylase	EC:1.14.11.2	Arginine and proline metabolism	ko00330	deepkoala