Genomic Location: Contig00010:433406...519855
NR annotation: XP_028410970.1, guanine nucleotide exchange factor VAV2-like isoform X2 [Dendronephthya gigantea]
Species Paragorgia papillata · all data for this species · gene families
| CDS |
| Ppa0G015020 |
| Transcript |
| Ppa0G015020 |
| Protein |
| Ppa0G015020 |
| UniProt accession | Description |
|---|---|
| P52735 | Guanine nucleotide exchange factor VAV2 OS=Homo sapiens OX=9606 GN=VAV2 PE=1 SV=2 |
| Q60992 | Guanine nucleotide exchange factor VAV2 OS=Mus musculus OX=10090 GN=Vav2 PE=1 SV=1 |
| P15498 | Proto-oncogene vav OS=Homo sapiens OX=9606 GN=VAV1 PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002927 (this species only) |
| Ubiquitin family | UBD|Other|SH3 · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00017 all species → | SH2 | SH2 domain | Domain | Interproscan |
| PF00621 all species → | RhoGEF | RhoGEF domain | Domain | Interproscan |
| PF00018 all species → | SH3_1 | SH3 domain | Domain | Interproscan |
| PF00169 all species → | PH | PH domain | Domain | Interproscan |
| PF00307 all species → | CH | Calponin homology (CH) domain | Domain | Interproscan |
| PF00130 all species → | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000980 all species → | Domain | SH2 domain | Interproscan |
| IPR000219 all species → | Domain | Dbl homology (DH) domain | Interproscan |
| IPR001452 all species → | Domain | SH3 domain | Interproscan |
| IPR002219 all species → | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR036860 all species → | Homologous_superfamily | SH2 domain superfamily | Interproscan |
| IPR036028 all species → | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR001849 all species → | Domain | Pleckstrin homology domain | Interproscan |
| IPR035899 all species → | Homologous_superfamily | Dbl homology (DH) domain superfamily | Interproscan |
| IPR036872 all species → | Homologous_superfamily | CH domain superfamily | Interproscan |
| IPR001715 all species → | Domain | Calponin homology domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR001331 all species → | Conserved_site | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45818 all species → | PROTEIN VAV | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0016477 all species → | Biological Process | cell migration | Interproscan |
| GO:0043087 all species → | Biological Process | regulation of GTPase activity | Interproscan |
| GO:0035556 all species → | Biological Process | intracellular signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K05730 | VAV; guanine nucleotide exchange factor VAV | - | Lipid and atherosclerosis | ko05417 | deepkoala |
