Gene detail

Detailed information of Ppa0G069670 in Paragorgia papillata

Genomic Location: Contig00083:111351...112196
NR annotation: CAB4000328.1, E3 ubiquitin- ligase SIAH1 [Paramuricea clavata]
Species abbreviation PPAPI · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P61092	E3 ubiquitin-protein ligase SIAH1A OS=Mus musculus OX=10090 GN=Siah1a PE=1 SV=1
Q920M9	E3 ubiquitin-protein ligase SIAH1 OS=Rattus norvegicus OX=10116 GN=Siah1 PE=1 SV=2
Q8IUQ4	E3 ubiquitin-protein ligase SIAH1 OS=Homo sapiens OX=9606 GN=SIAH1 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007542 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF21361 all species →	Sina_ZnF	Sina, zinc finger	Domain	Interproscan
PF03145 all species →	Sina_TRAF	Sina, TRAF-like domain	Domain	Interproscan
PF21362 all species →	Sina_RING	E3 ubiquitin-protein ligase sina/sinah, RING finger	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR013083 all species →	Homologous_superfamily	Zinc finger, RING/FYVE/PHD-type	Interproscan
IPR004162 all species →	Family	E3 ubiquitin-protein ligase SINA-like, animal	Interproscan
IPR018121 all species →	Domain	Seven-in-absentia protein, TRAF-like domain	Interproscan
IPR013010 all species →	Domain	Zinc finger, SIAH-type	Interproscan
IPR008974 all species →	Homologous_superfamily	TRAF-like	Interproscan
IPR049548 all species →	Domain	E3 ubiquitin-protein ligase Sina-like, RING finger	Interproscan
IPR001841 all species →	Domain	Zinc finger, RING-type	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45877 all species →	E3 UBIQUITIN-PROTEIN LIGASE SIAH2	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006511 all species →	Biological Process	ubiquitin-dependent protein catabolic process	Interproscan
GO:0007275 all species →	Biological Process	multicellular organism development	Interproscan
GO:0031624 all species →	Molecular Function	ubiquitin conjugating enzyme binding	Interproscan
GO:0043161 all species →	Biological Process	proteasome-mediated ubiquitin-dependent protein catabolic process	Interproscan
GO:0061630 all species →	Molecular Function	ubiquitin protein ligase activity	Interproscan
GO:0008270 all species →	Molecular Function	zinc ion binding	Interproscan
GO:0005515 all species →	Molecular Function	protein binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04506	SIAH1; E3 ubiquitin-protein ligase SIAH1	EC:2.3.2.27	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.