Gene detail

Detailed information of Ppa0G102210 in Paragorgia papillata

Genomic Location: Contig00119:167016...176208
NR annotation: XP_028405281.1, hydroxymethylglutaryl-CoA synthase 1-like [Dendronephthya gigantea]
Species abbreviation PPAPI · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P23228	Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Gallus gallus OX=9031 GN=HMGCS1 PE=1 SV=1
Q01581	Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=HMGCS1 PE=1 SV=2
Q5R7Z9	Hydroxymethylglutaryl-CoA synthase, cytoplasmic OS=Pongo abelii OX=9601 GN=HMGCS1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005551 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08540 all species →	HMG_CoA_synt_C	Hydroxymethylglutaryl-coenzyme A synthase C terminal	Domain	Interproscan
PF01154 all species →	HMG_CoA_synt_N	Hydroxymethylglutaryl-coenzyme A synthase N terminal	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR016039 all species →	Homologous_superfamily	Thiolase-like	Interproscan
IPR010122 all species →	Family	Hydroxymethylglutaryl-CoA synthase, eukaryotic	Interproscan
IPR013746 all species →	Domain	Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain	Interproscan
IPR013528 all species →	Domain	Hydroxymethylglutaryl-coenzyme A synthase, N-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR43323 all species →	3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0016746 all species →	Molecular Function	acyltransferase activity	Interproscan
GO:0004421 all species →	Molecular Function	hydroxymethylglutaryl-CoA synthase activity	Interproscan
GO:0008299 all species →	Biological Process	isoprenoid biosynthetic process	Interproscan
GO:0006084 all species →	Biological Process	acetyl-CoA metabolic process	Interproscan
GO:0010142 all species →	Biological Process	farnesyl diphosphate biosynthetic process, mevalonate pathway	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01641	HMGCS; hydroxymethylglutaryl-CoA synthase	EC:2.3.3.10	PPAR signaling pathway	ko03320	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.