Gene detail

Detailed information of Ppa0G120120 in Paragorgia papillata

Genomic Location: Contig00146:563192...594917
NR annotation: CAB3992965.1, tyrosine- kinase ZAP-70 isoform X1 [Paramuricea clavata]
Species Paragorgia papillata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Ppa0G120120

ATGCTTAGTTATTTTCATAGTGGTGTGCAATCACTGGGTTCTACAAATGCCAAGAGAATCATAAAAATAACAAGCAAACACAATATTGCAATTAATGCCTGCTTTGCATCAGGTAACATCTGCTTGGATGTTTGCATCGAAATTGCCAAACTCATGGGCATAGCACCTGTGGCCTTGGATTTTTTTACACTAATGACCACTGACTGTGAACACTGTCTCAGACCAAATCGTCAAACCAGACAGGAGTGTACCAAGGAGAACGACCATTACCTCAATCCCAAAAGATTGCTTCATGCAGAAGAGTGCTCTTCAAAAGTCTTTTTCTTCAGACTGGCGTTCAAGGCCATTCCTGGACCAGATATTAAAATGGTGGACAAAGGGGCCTTTGCATATTTTGTTATGCAGTGTCGATGGGATTATCTGAACGGCAGAATCACAGATCTAAATAAAAAGGATCATCTTACACTACTTATTCTGGAGTCTATAATAAGGGGTCATGAAAATAATGTAAATGGCAAAGATGTATTGGACAATCCGAAAAAGTATGGTCTTATGCACATGTTCATCGACAATGAATTTAGTGTCAGGGAGATCAAGAACCATTTAAAAAAGCAGATCTCTCAATTCAGGACGTGCCAAGACGATGTTGATAAAGCAAAGAATTCATTTCTATGTGTTCTTGAGGGTGTTGCAGATTTTGGTATCACTAAAATTGTTGTACATAAGTGGGAGATAATAATCTCTGCTAATGGTTTGAAAAAGAGACGCACGTACAAAGATGAAGGGCCAGGTACAACGAAAGATGAAATCATAAGCGACTATAAAGACATTGAATACCTTGAGATAAAACAATCAGAGTCATCCGAGATCATTCATATATCCAGGATGCAAGGATTTTTAGAGAAAGAAAGTTTAATCACGCTTATTGAAGGGTTTTACCGACTTTTGGTCAATCAGTATAAGGCGCTGACAAAGTGTAAGATTACACCAAGGAGAGAATTTGAAATACACGGACCTATTGAGAGAAAGAAAGCAGAGGCCTTGCTAAAAGCGGTTGACTGTCCAAACGGCGACCGTACTGGTGTTCATATGATTCGTAGAGGCCGACAGAAATTTGATTCTTATAATCTATCCTTTATCAACGGAAGCGAAATCAGACATTACGAAGTAGTGATGTCACCAACTGGATGCTGTGGCATTGCTAATGGACCACAATTTGACAGTGTCGCAGAGATGTTGGAATTCTACAAAACTGCACAGGCGGGTTTTCCGACAACTTTGAAAAAGTACTGTCCCATCCCAAGAGAAGGTTTGTGTGCCCTGTTTGACGAACAGATAGTTGTCGAAGCTCCTCGTCCACCATCTACATCACGACCAATAAATCCGGAGTATCAGTTTGTGCAAATTAGAAATATGGAGCTGCAGAAACTCAATCACACGTTCACGTGTGGGAATTTTGAAGATAGGTTTTTTAAGGCTCGTTGGTTGAAAGGAGATGATTCTGGATGTCAGGAAGTATTTTGCCGCCGTCTCGCGCCATCACGTACAGAAAAATTTAAAGATAAAGTGATTAGTTCTGCTGAAAAAATGTCTTCACTGGTTCATCGTAACCTCGTTCAGTTTCATGGTGTGTGCTTTTTCAATGACCAAAATACTTACCTTGCTTTTGAGTGGATTCCGTCCGGCACCTTAGACGACTACCTGATCAAAGAAGCCGATGTTACCGTGGAAACAATAATAACGTTTGCCGCTCAGATATCAGAAGCGTGTATGTACCTTCACCAGAATAACTACGTTCATGTAAGCAATGAACAGGTAAAAGTTAGCGACGTGTCTGTGCCTTGCCTCAGAGAAGAAGACCTGTTGTTGCAAACATCGGAAGAAGCAAATAGGAGTCCATGGAAAGCACGGGAGTGTTTTCTTGGTAGACCATACAGCAAGGAATCTGATGTTTGGGCTTTTGGTGTCGTTCTGTGGGAGATGTTTATGAAAACTAAACCATTTCAAAACATGACCGACGAAATGGTAAGAGCTACTGAGACATTACTATATTTCGATTGTTGTTTCTACACTGCCTACGCAGCACGCTACTTTTATATAAATAACCTATACTTATCTCCAGTTTCTTTCTGTCGAAATCAAGAAGTTGGTAAAATTATGAAATCTTGTTGGTTTACTGAACCACAGCGGCGTCCAACGTTTGGGAGTATTGTCATCAAATTGCGATCGATCTCGGCGAATTTGAGCGCTCAAGAAAAGCATCGTAGTATTCCTCAAACAGTTGATGAGAAATTCACTATTGAACCCTTGATGATGAACAAGGCGTTGAACGCATTTGTTGAACAGAGACATGCGCCATGCGGGATATTGAGCCGCGAGGCACGGTGTGGTCGCCTGGTAATGAGTTGCCGACCAAAGACAGAAGATCTGCGTGAAGCTCTGTTGAGATCTGATGAAACGCCTGATGCAAGACCAGGGGATACATCTGGGGATCAACGTCATAACACCATATCCGAAGTGGAATCTGAACCATCAGACCAAGAAACCATTAAGGTGGCGGCGGACGTCGCCGAAACCCCCGACGAAGTTTCATCTCTTGCTTCAGGGCCCTTGGCTTCCAGACCTCTGGCTAATTCAGAACCTCTGCTTTCACGACCTCTGTCTTCCCGACCTTTGACTTCAGGATCTCTGGCTTCCAGACCTGTGGCTTCAGGACATTTAACTTCAGGACCTATGCCTTCAGGACCTCAGATTTGGCAATCTCAGGCTTTGATTACCCAAGCTTCGAAACCTCTGACTTCCCGACCTTTGACTTCGAGACCGTTGACCTCAACGTCTCCGCTCATAAATAAGACTGATGGTTCGCCTAACTCTAGTAAGAGTGGTTACGTTACCGTTGCGGGTCTGAACAATCATGAAAGAACTACACCTTCACAGTCGCACGCTGTTGATGAACACAGAGACGACTCAACTAAGTCCCTCTTGAGCTCCGGCGATTTTATGATCCAAAACCTCTCGAACCGTGACATTTTTAGCGACATTCTTTTGGGCTCTGGAAACACACCCGAAGATACTAAAAAATCTTTCGACACATCGAGCTACCCTACGAGTAAATCATTTATTGAGGTAGCGTCAAGCAATAGCGGGAATGTCGGTTCAGAGGTTAAACAGCTCGCGAAGGATGGGTGTAGTCGAGGCGCGTACTCTCGAGTCCCAAGCACGAACTATCAGGGATTATCAGACAAGAATAAAGTGGCCAAAAAGTCGAATTACACTCAACTGTTCAATGATGTTTCACATTACCAAGCGCCTGCCGTTCCAGGCGATATGGGTTTCCAAGACAGGGATCCATTTCGCGAAATAGGAGCCGGGAAAACGTTAGAGACGGAAAGCGAACCAAACCGGAGTTCCCCTGTGATTTCTGATTACGTTGGAAAGAGTGATCCGAAACGAAGTTCTCCTGCGATTTTTGATTACGTTGGAAAAAACGATCCGAAACGAAGTTCTCCTGCAATTTCTGATTACGTTGGAAAAAGCGAACCAAAGCGACGTTCTCCTGTGATTTCTGATTACGTTGGAAAAAGCGATCCAAAACGGTGTTCCCCTGCGATTTCTGATTACGTTGGAAAAAACGATCCGAAACGAAGTTCTCCTGCAATTTCTGATTACGTTGGAAAAAGCGAACCAAAGCGACGTTCTCCTGCGATTTCTGATTACGTTGGAAAAAGCGAACCAAAACGAAGTTCTCCTGTGATTTCTAATTACGTTGGAAAAAGCGAACCAAAACGGTGTTCCCCTGCGATTTCTGATTACGTTGGAAAAAGCGATCCAAAACGGTGTTCCCCTGTGATTTCTGATTACGTTGGAAAGAACGAACCGAAACGAGGTTCCCCTGTGATTTCTGATTACGTTGGAAAGAACGAACCGAAACGAAGTTCCCCTACGATTTCTGATTACGTTGGAACAAGTCCATCTCAAACCGGGAGGAGAAATTCACCAGTTAGACTCGTTGGAGTTGACAGAAACGAAGAAGTCGGAGAGACGATTTCCGTGAACGAGGACCATGATACTCCGGAAGTCGTGCCACAAGATTCAAGCTTTGGAAGATGGGACCCGTTTGCCGAGTTCTCTCGTACGAACGATGATGCACCATCGCTCCTTGCGCGCTCCCGCACTCCCCCACTCAGTAAGGCTCCGGAGGAATCGGGCGAGAAGGAAGGACTTCCCGTAGGTAGAAGAAAAGTGGATGTCCCATCGCTTCAAAGAAGCGTGATTTCGGCGGACGACAAGAACGACAGGATCTCGAACTTAATAAAAGCTGTAAGGAGAGAACCGATTGTTGGTAATACCTACCATCTTACTAGTAGAACGGAACCCGCCGATAAACAACGACACACTCTCCAGGTCTCTAGGCCTGACCTTTCGTCGTCGAGTCAGGCTGAAAACAGACATGAAACGCCAGAAAGAAATCCCCCATCGGGTAATGATGGTACGGATGGAGGTCAGCCACCCAGTAAAGACAAGCAGAAAGCAAGTCGCAGAGTATCTGATATTGACTCGGCGTATGCCAAGATCGGAATACTCGAAGTCGACGCTGGGTCAAATACTTATCAGATGGTGGTTAACCCTCGTGAGACGTCTGATGAGACTGTTTTAGGAGCCGTTGGAGGAGCACGAAAGACGGAAGTTTTCGAAGAAAGTATGAAATCGCATCAAATTCCTTTCAACAATCTTACATTCAATGACATGGAGAAAAATTTGGGGCAGGGTGCATTCGGTGTAGTGCGCAGGGCGAAGTTTACTAGAACGGCTCAGCATAAAACAAGACCAAGCACGGATGTTGCTGTGAAGTGCCTGAAAGATAACGCTTCGGAGATCTACAAAAACAGTTTCAAGCAAGAAGCTGTCAATCTCATGAAGTTGGATAACAAATTTATTGTAAAGTTCCTGGGAATATCATACGATAACGAGGGAAAGTTGCTGCTGGTTACAGAGCTTGTCCCGCAAGGATCGTTGGATAGCTATTTGAAAGATCCAAAAAATTTAAGAATTCTCGGAACTGAAGTACTTTTACAATTTGCCATTCAGATCACCATGGGGATGCAATATCTGGAAAGTAAAAAACTTGTGCATCGAGATCTTGCAGCTCGAAATATATTGGTCGCCACTGAATCACATGTGAAGATCAGCGACTTCGGACTGAGTCGGATTTACGACGACGAGTACTACCGAAGTCACAGGGAAAACCAAAAACTGCCTATCAGATGGTTGGCTCCTGAGTGCTTGGAGCAGAAGAAGTTTACTGTCAACAGTGATGTATGGAGTTTAGGAGTTACCCTTTGGGAGATGTTTTCTTATGGCAAACGACCATATGAGGGTGTGACGTTCAAGACTGCTGGAGAGCTCATAGACTACTTGAAGCAAGGCAACCAACTTGAGAGGCCACAGGCGTGTCCAGAGGAAATTTACGTTCACATAAGAGAGTGCTGGCACTTGCCACCTACAAAGAGAATCTCGTTCTTTCTTCTCAAGACCTTCCTCGAGGAAATCTTGAAGGAAAAATACTCGAAGAAGCCATACTTCATGTAG

Transcript

Ppa0G120120

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P41240	Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1
P41241	Tyrosine-protein kinase CSK OS=Mus musculus OX=10090 GN=Csk PE=1 SV=2
P32577	Tyrosine-protein kinase CSK OS=Rattus norvegicus OX=10116 GN=Csk PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0014415 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07714 all species →	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	Domain	Interproscan
PF00017 all species →	SH2	SH2 domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001245 all species →	Domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	Interproscan
IPR008266 all species →	Active_site	Tyrosine-protein kinase, active site	Interproscan
IPR036860 all species →	Homologous_superfamily	SH2 domain superfamily	Interproscan
IPR000980 all species →	Domain	SH2 domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR051286 all species →	Family	Janus Kinase (JAK)	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR020635 all species →	Domain	Tyrosine-protein kinase, catalytic domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45807 all species →	TYROSINE-PROTEIN KINASE HOPSCOTCH	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004715 all species →	Molecular Function	non-membrane spanning protein tyrosine kinase activity	Interproscan
GO:0005126 all species →	Molecular Function	cytokine receptor binding	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0007259 all species →	Biological Process	cell surface receptor signaling pathway via JAK-STAT	Interproscan
GO:0019221 all species →	Biological Process	cytokine-mediated signaling pathway	Interproscan
GO:0030154 all species →	Biological Process	cell differentiation	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0004713 all species →	Molecular Function	protein tyrosine kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K04447	JAK2; Janus kinase 2	EC:2.7.10.2	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.