Genomic Location: Contig00314:1101476...1108198
NR annotation: CAB3983955.1, sphingomyelin phosphodiesterase isoform X1 [Paramuricea clavata]
| CDS | |||||
| Ppa0G207470 | |||||
| Transcript |
| Ppa0G207470 |
| Protein |
| Ppa0G207470 |
| Uniprot term | Description |
|---|---|
| Q0VD19 | Sphingomyelin phosphodiesterase OS=Bos taurus OX=9913 GN=SMPD1 PE=2 SV=1 |
| Q04519 | Sphingomyelin phosphodiesterase OS=Mus musculus OX=10090 GN=Smpd1 PE=1 SV=2 |
| P17405 | Sphingomyelin phosphodiesterase OS=Homo sapiens OX=9606 GN=SMPD1 PE=1 SV=5 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00149 | Metallophos | Calcineurin-like phosphoesterase | Domain | Interproscan |
| PF19272 | ASMase_C | Acid sphingomyelin phosphodiesterase C-terminal region | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004843 | Domain | Calcineurin-like phosphoesterase domain, ApaH type | Interproscan |
| IPR045473 | Domain | Sphingomyelin phosphodiesterase, C-terminal domain | Interproscan |
| IPR008139 | Domain | Saposin B type domain | Interproscan |
| IPR029052 | Homologous_superfamily | Metallo-dependent phosphatase-like | Interproscan |
| IPR011001 | Homologous_superfamily | Saposin-like | Interproscan |
| IPR011160 | Family | Sphingomyelin phosphodiesterase | Interproscan |
| IPR041805 | Domain | Acid sphingomyelinase/endopolyphosphatase, metallophosphatase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10340 | SPHINGOMYELIN PHOSPHODIESTERASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0016787 | Molecular Function | hydrolase activity | Interproscan |
| GO:0004767 | Molecular Function | sphingomyelin phosphodiesterase activity | Interproscan |
| GO:0006685 | Biological Process | sphingomyelin catabolic process | Interproscan |
| GO:0005615 | Cellular Component | extracellular space | Interproscan |
| GO:0005764 | Cellular Component | lysosome | Interproscan |
| GO:0008081 | Molecular Function | phosphoric diester hydrolase activity | Interproscan |
| GO:0046513 | Biological Process | ceramide biosynthetic process | Interproscan |
| GO:0061750 | Molecular Function | acid sphingomyelin phosphodiesterase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12350 | SMPD1, ASM; sphingomyelin phosphodiesterase | EC:3.1.4.12 | Necroptosis | ko04217 | deepkoala |