Gene detail

Detailed information of Ppa0G260280 in Paragorgia papillata

Genomic Location: Contig00406:7414079...7431976
NR annotation: CAB3981484.1, lipoyl synthase, mitochondrial [Paramuricea clavata]
Species abbreviation PPAPI · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O43766	Lipoyl synthase, mitochondrial OS=Homo sapiens OX=9606 GN=LIAS PE=1 SV=3
Q6GQ48	Lipoyl synthase, mitochondrial OS=Xenopus laevis OX=8355 GN=lias PE=2 SV=1
Q5BIP7	Lipoyl synthase, mitochondrial OS=Bos taurus OX=9913 GN=LIAS PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004493 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF04055 all species →	Radical_SAM	Radical SAM superfamily	Domain	Interproscan
PF16881 all species →	LIAS_N	N-terminal domain of lipoyl synthase of Radical_SAM family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR003698 all species →	Family	Lipoyl synthase	Interproscan
IPR007197 all species →	Domain	Radical SAM	Interproscan
IPR031691 all species →	Domain	Lipoyl synthase, N-terminal	Interproscan
IPR006638 all species →	Domain	Elp3/MiaA/NifB-like, radical SAM core domain	Interproscan
IPR013785 all species →	Homologous_superfamily	Aldolase-type TIM barrel	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10949 all species →	LIPOYL SYNTHASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0009107 all species →	Biological Process	lipoate biosynthetic process	Interproscan
GO:0016992 all species →	Molecular Function	lipoate synthase activity	Interproscan
GO:0051539 all species →	Molecular Function	4 iron, 4 sulfur cluster binding	Interproscan
GO:0003824 all species →	Molecular Function	catalytic activity	Interproscan
GO:0051536 all species →	Molecular Function	iron-sulfur cluster binding	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K03644	lipA, LIAS, LIP1, LIP5; lipoyl synthase	EC:2.8.1.8	Lipoic acid metabolism	ko00785	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.