Gene detail

Detailed information of Ppa0G407930 in Paragorgia papillata

Genomic Location: Contig00588:240986...274292
NR annotation: XP_028413049.1, cyclin-G-associated kinase-like [Dendronephthya gigantea]
Species Paragorgia papillata · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Ppa0G407930

ATGGCTGACATATTTCGATCGGCATTCGGTATCTTTGGGAGCACGAAGAACGACAGCGATTTTGTAGGTCAACGAGTGGACATTGGATCTGTTCAACTGAGGGTGAAAAAATTAATAGCTGAAGGCGCTTATGGATTCGTGTTTATTGCTCAGGACGTGTCTTCTGGAAAGGATTATGCATTAAAACGACTGATGGCAGCAGATGAGGCAGCTAATAAGGCAATAATTCAAGAAATTTGTTTCATGAAACGTCTACGGGGACATCCAAACATTGTTCAATTTTTAAATGCTGCATCAATTGGAGCAGAAGAATCAGAAAATGGAATGTCAGAATTTTTAATTTTAACAGAATTATGTACAGGTGGGCAACTTATCAAGTGGTTTAATGACAGACAGGGAAAACCAGTACCTTCCAATCAAGTGCTAAGAATTTTTCATCAGATTTGCAGGGCTGTCTCTCATATGCACAAACAAAATCCACCAATAATTCATCGTGATCTGAAGATTGAAAATCTACTTTTGAGTTCTCGTGGTCAGATCAAACTGTGTGACTTTGGTAGTGCAACTACAAAATCTTTGTATCCAAATGAATCCTGGTCCTCAGTTGAGAGAAGTCTGGTTGAGGATGAGATACAGAGAAATACAACTCCAATGTATCGTGCACCAGAAATGGTTGATCTTTATAGCAATTATCCACTAACAGTGAAGTCTGACATCTGGGCATTGGGCTGTTTATTGTATATGTTATGTTATATGGATCATCCATTTGATGATGGAGCCAAATTGAGAATATTAAATGCAAAGTTTACCTTGCCAGAATTTGACAAAGAATATGGATTGTTTCACGCTTTGATAAATAAAATGTTGCAAGTTGATCCTCTTAAGCGGTCCGACATCACTGAAATTGTGGCTGATGTGGAAGGAATAGCTTTATCTAAATATGTCGAATTGAAAGGATCCATTTTTCAAGGGGAGGAATCATTGACTTCTACTAGTCAAGATGGACAAGATCAATCTGCTGGAAATGCAGTATTTGGTGGAGTGGTCAAAGGTGCAGGAAACTTCTTTTCAAACATTAAAGATATGTCTAGCAAGATGGTACAGTCAGTTGCTGGATACGTCAAGAGTGATCTAGATATTTCATACGTTACATCCAGAATATTAGTCATGCCAATACCAGGTGAAGGAATTGAGTCGACGTATAAGAACAGTGTAGACGATGTGCAAGTATTCTTGGATACTAAACATCCATCTCGATTTGCTGTCATTAATTTATCTCAACGTCCAACAAAATTAAAAGGAAAGGTGTTTGATTGTGACTGGTCTCCAAAGAGAGCACCGCGATTAGAGAAGATTTTAATAGTATGCAAGAAGATTGTAGCTTGGTTTAAAACCGATAAAAGAAATGTTGTTGTTGTACAATGCCCGGACGGAAAGTTGACATGTGGATCACTTGTCACATCTTTGTTTTTATATTGTCATCTCTTTATGTCTCCTGAATGTGCTTTTGAAATGTTTAATATTCGTCGTCAAAATATGTCAACAAGAATTGTACCAACTCCATCACAAAAACACTACTTCAATTACATAACTCAGTTGGTGAATGATCCTGATGCTAAGCCTCATAAGTGTTATCTCGTTCTAAACTCATTGTCAATGGACCCTGTTCCTCTCTTTAATAAAGCCAGAAAGGGATGCAGGCCATTCATTGAAGTTTACAGTGGTGATAAGAGAGTACTTACAACTGCTTGTGAAATCGAGAAATTAAGAGAATTTACAGTTTTAGATCAACAAATCGACTTTAAGTTACGCCTTGAAATTCAAGGAGATGTCACCGTGTGTGTTTACCACGGCAGATCAACTCTTGGTGGTAAAGTTCAAGGAAAACTTACCTCTATTCCAATGTTCCAACTTCAATTTCACACTGGCTTTGTTGCCAAGAAAGCAAAGAAGATGGTGTTCATTAAAGAGGATGTCGACATTCTTGACGCAAATAATTTAAGTAGATTTGCTGAAAATTTTAACGTTACGTTGGAGATTTCGTGCGACGAAGATCATTGTAACGATGCCACATGTGTCTGGGAGACAAGACAAAATGAAAACGCCACACGACAATTGTTATTTACTACTTCTGAGGAGTACCTTCAGTGTCAGGAGGACTTTGTGTTAGGTGATGACCGAGAGATGTGCTACAGGGAACAATTTGAGCTTGATAGAAAATCAAGAAAAGAAACCTCGAGTAAGGGGAACAACAAAGGTACGAGTGAGAAACAAACGACAATAAACAAGGCAAGTGAAGAAAAAACAACTGGTTCATTTTTCGAGAAGCTTAATTGGGAAGACGAAGAAGAACCTCTGAAGGAGAGCAGTGGTAGTGAAGGTGATTCTGATAATGATTGGGAAGCTTTGCGAAATCCTACTAGACCTGATAATAATGATGTCCGTAGGAACAATGAAGAACAGTCGTTTGATTTCTTTACTGAAAGTGAAGGCCAAAGCACTAGTAAACAGGAGAATGTTGATTTGTTTAATCTTAAAGAGAAAGAGAAAGCTGCGAGTGACAATGAATTGAAAGATGATCATCCCGAAGAAGATCTTCTTGGACTTGGAATTGACACTGCTGAAGAAAGTGTTGAGACTGGTACTACTAATACGAACTTACCATCTCCTAATTCTAGAAAAGACACAAGGCATTCCAGCCTAGGTGAACAGCAGCTTCGTACCGACTTTGATCTTTTAAATATATTAAATGATCATTCCAAGGAAACCTCAGATGTCGATCCACTTGGTTTGCCTCAAAATGTTTCAGGAATGAAGCGTAATAAAAGTGCTGACGATATCTTGATTCTTTCCCCTGGTGATCATTCAGTTAGCGAAGATGATTTCTTTGGTGCTTTTAACAAGCCTTCTAATCATAATTCATCTGCTTCTAATTCATTCGATCTGTTTGGTGCCCCGGGTGCGAAAAATACAGACTTTTTTGGTGATTTGGAAACATCCGCTTCCAATTCTGGCAAGAACAGTCCAATCTTAACACCTCAAGTGAATGTTTCTTCGAATCAAAATAATTTTGTAAACCCACCAAAATCTACTCAAGAAAATGATCCGTTTGCAGACCTAGGAGGCTTGGCCGGTTCTAACAGTGGATTTGGAAAGTTTGGTGGTAGTGGTCCGCGAAAGCCTACAGCAGATCCATTTTCATCATTTGGGAAACCGACAGGCTCTCCAAAACAACCAACTGTAGCAAAAGGATTTCAAAATGGATCACCACTAGGAAGTAAAGCTCCTCTTAAAACTCCAGCTCAGAAGCCTAACTACACACCAAGCTATGCTTCTGGAAGTTCTGTGTTTGGAAGCTATGGTCTGAAGGATATAAACCAAAAAGTTGCAAAAGATGAGTTCAGTGATATATTAAATTCTCACGGTTTTAAAGCGTCTTCATCTGAAAGTGGACCTAATACAATAAATTCTTTAAGAAAACAAGTTGAGGTAGAAGATGATCCCGTGAAAGCCAAGGTACGAAGTTGGAGTGAAGGTAAAGAGAGAAATATTCGAGCTTTGTTATGTTCATTGGATACTGTACTTTGGGAAGGTGAAGAGAGATGGAAGAAAGTTGGAATGCACGAGTTAGTCAGTGCTGACCAGGTAAAGAAATGTTACAGAAGAGCGGTTCTTTCTGTTCATCCTGATAAGCTAATTGGTGCTCCAGAAGAACATTTAGCGAGAGCAATTTTTATTGAACTAAACGAATCATGGGCTGCTTTTGAAGAAAGCGGTTCAAAATCACTTTACTAA

Transcript

Ppa0G407930

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
O14976	Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2
Q99KY4	Cyclin-G-associated kinase OS=Mus musculus OX=10090 GN=Gak PE=1 SV=2
P97874	Cyclin-G-associated kinase OS=Rattus norvegicus OX=10116 GN=Gak PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004023 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF10409 all species →	PTEN_C2	C2 domain of PTEN tumour-suppressor protein	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR029021 all species →	Homologous_superfamily	Protein-tyrosine phosphatase-like	Interproscan
IPR001623 all species →	Domain	DnaJ domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR029023 all species →	Domain	Tensin-type phosphatase domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR014020 all species →	Domain	Tensin phosphatase, C2 domain	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR035892 all species →	Homologous_superfamily	C2 domain superfamily	Interproscan
IPR036869 all species →	Homologous_superfamily	Chaperone J-domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22967 all species →	SERINE/THREONINE PROTEIN KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0035612 all species →	Molecular Function	AP-2 adaptor complex binding	Interproscan
GO:0045747 all species →	Biological Process	positive regulation of Notch signaling pathway	Interproscan
GO:2000369 all species →	Biological Process	regulation of clathrin-dependent endocytosis	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K08855	GAK; cyclin G-associated kinase	EC:2.7.11.1	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Paragorgia papillata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Paragorgia papillata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →