Genomic Location: NC_064038.1:15618211...15620048
NR annotation: XP_001630840.2, peptidyl-prolyl cis-trans isomerase E [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5510374 |
| Transcript |
| rna-XM_001630790.3 |
| Protein |
| XP_001630840.2 |
| UniProt accession | Description |
|---|---|
| A4FV72 | Peptidyl-prolyl cis-trans isomerase E OS=Bos taurus OX=9913 GN=PPIE PE=2 SV=1 |
| Q9UNP9 | Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1 |
| Q9QZH3 | Peptidyl-prolyl cis-trans isomerase E OS=Mus musculus OX=10090 GN=Ppie PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000361 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00160 all species → | Pro_isomerase | Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD | Domain | Interproscan |
| PF00076 all species → | RRM_1 | RNA recognition motif | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR034168 all species → | Domain | Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif | Interproscan |
| IPR000504 all species → | Domain | RNA recognition motif domain | Interproscan |
| IPR020892 all species → | Conserved_site | Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site | Interproscan |
| IPR002130 all species → | Domain | Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain | Interproscan |
| IPR016304 all species → | Family | Peptidyl-prolyl cis-trans isomerase E | Interproscan |
| IPR012677 all species → | Homologous_superfamily | Nucleotide-binding alpha-beta plait domain superfamily | Interproscan |
| IPR035979 all species → | Homologous_superfamily | RNA-binding domain superfamily | Interproscan |
| IPR029000 all species → | Homologous_superfamily | Cyclophilin-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11071 all species → | PEPTIDYL-PROLYL CIS-TRANS ISOMERASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003723 all species → | Molecular Function | RNA binding | Interproscan |
| GO:0003755 all species → | Molecular Function | peptidyl-prolyl cis-trans isomerase activity | Interproscan |
| GO:0006457 all species → | Biological Process | protein folding | Interproscan |
| GO:0000413 all species → | Biological Process | protein peptidyl-prolyl isomerization | Interproscan |
| GO:0043231 all species → | Cellular Component | intracellular membrane-bounded organelle | Interproscan |
| GO:0003676 all species → | Molecular Function | nucleic acid binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K09564 | PPIE; peptidyl-prolyl isomerase E (cyclophilin E) | EC:5.2.1.8 | Chaperones and folding catalysts | ko03110 | deepkoala |
Transcript abundance of XP_001630840.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 11.11 | 15.05 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 5.95 | 8.09 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 6.09 | 7.87 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 9.80 | 11.99 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 5.20 | 6.69 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 3 | 15.46 | 25.85 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 8.85 | 10.75 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 11.91 | 12.59 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 8.04 | 11.47 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 10.56 | 14.14 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 8.50 | 9.57 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 15.20 | 22.73 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 12.60 | 14.43 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 3 | 17.60 | 28.42 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 9.26 | 11.08 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 3 | 7.83 | 9.54 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.