Genomic Location: NC_064041.1:14650224...14658827
NR annotation: XP_001630968.2, DNA polymerase iota [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5510511 |
| Transcript |
| rna-XM_001630918.3 |
| Protein |
| XP_001630968.2 |
| UniProt accession | Description |
|---|---|
| Q9UNA4 | DNA polymerase iota OS=Homo sapiens OX=9606 GN=POLI PE=1 SV=3 |
| Q6R3M4 | DNA polymerase iota OS=Mus musculus OX=10090 GN=Poli PE=1 SV=1 |
| Q9VHV1 | DNA polymerase iota OS=Drosophila melanogaster OX=7227 GN=PolI PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0010062 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00817 all species → | IMS | impB/mucB/samB family | Family | Interproscan |
| PF11799 all species → | IMS_C | impB/mucB/samB family C-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036775 all species → | Homologous_superfamily | DNA polymerase, Y-family, little finger domain superfamily | Interproscan |
| IPR001126 all species → | Domain | UmuC domain | Interproscan |
| IPR043128 all species → | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| IPR043502 all species → | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR017961 all species → | Domain | DNA polymerase, Y-family, little finger domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46404 all species → | DNA POLYMERASE IOTA | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003684 all species → | Molecular Function | damaged DNA binding | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| GO:0003887 all species → | Molecular Function | DNA-directed DNA polymerase activity | Interproscan |
| GO:0019985 all species → | Biological Process | translesion synthesis | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03510 | POLI; DNA polymerase iota | EC:2.7.7.7 | DNA repair and recombination proteins | ko03400 | deepkoala |
Transcript abundance of XP_001630968.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 2.14 | 2.47 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 2.13 | 2.42 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 2.59 | 3.08 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 1.73 | 1.84 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 2.06 | 2.22 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 1.60 | 2.83 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 1.36 | 2.10 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 2.34 | 2.74 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 1.18 | 1.92 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 2 | 1.08 | 1.84 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 1.74 | 2.03 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 2 | 1.44 | 2.21 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 2 | 1.38 | 2.23 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 1 | 0.86 | 2.58 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 2.06 | 3.16 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 0.71 | 2.14 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.