Detailed information of XP_001633987.2 in Nematostella vectensis

Genomic Location: NC_064037.1:10058997...10081834
NR annotation: XP_001633987.2, pre-mRNA-processing-splicing factor 8 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q6P2Q9Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2
Q99PV0Pre-mRNA-processing-splicing factor 8 OS=Mus musculus OX=10090 GN=Prpf8 PE=1 SV=2
P34369Pre-mRNA-splicing factor 8 homolog OS=Caenorhabditis elegans OX=6239 GN=prp-8 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004368 (this species only) · gene tree & orthology
Ubiquitin familyUBD|Other|Jab_MPN · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF08083
all species →
PROCNPROCN (NUC071) domainDomainInterproscan
PF08082
all species →
PRO8NTPRO8NT (NUC069), PrP8 N-terminal domainDomainInterproscan
PF10596
all species →
U6-snRNA_bdgU6-snRNA interacting domain of PrP8DomainInterproscan
PF08084
all species →
PROCTPROCT (NUC072) domainDomainInterproscan
PF12134
all species →
PRP8_domainIVPRP8 domain IV coreDomainInterproscan
PF01398
all species →
JABJAB1/Mov34/MPN/PAD-1 ubiquitin proteaseFamilyInterproscan
PF10597
all species →
U5_2-snRNA_bdgU5-snRNA binding site 2 of PrP8DomainInterproscan
PF10598
all species →
RRM_4RNA recognition motif of the spliceosomal PrP8DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR012337
all species →
Homologous_superfamilyRibonuclease H-like superfamilyInterproscan
IPR012592
all species →
DomainPROCN domainInterproscan
IPR043172
all species →
Homologous_superfamilyPrp8 RNase domain IV, palm regionInterproscan
IPR021983
all species →
DomainPRP8 domain IV coreInterproscan
IPR043173
all species →
Homologous_superfamilyPrp8 RNase domain IV, fingers regionInterproscan
IPR012591
all species →
DomainPRO8NT domainInterproscan
IPR019580
all species →
DomainPre-mRNA-processing-splicing factor 8, U6-snRNA-bindingInterproscan
IPR042516
all species →
Homologous_superfamilyPre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamilyInterproscan
IPR027652
all species →
FamilyPre-mRNA-processing-splicing factor 8Interproscan
IPR012984
all species →
DomainPROCT domainInterproscan
IPR000555
all species →
DomainJAB1/MPN/MOV34 metalloenzyme domainInterproscan
IPR019581
all species →
DomainPre-mRNA-processing-splicing factor 8, U5-snRNA-bindingInterproscan
IPR019582
all species →
DomainRNA recognition motif, spliceosomal PrP8Interproscan
IPR037518
all species →
DomainMPN domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11140
all species →
PRE-MRNA SPLICING FACTOR PRP8Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0000398
all species →
Biological ProcessmRNA splicing, via spliceosomeInterproscan
GO:0017070
all species →
Molecular FunctionU6 snRNA bindingInterproscan
GO:0000244
all species →
Biological Processspliceosomal tri-snRNP complex assemblyInterproscan
GO:0005681
all species →
Cellular Componentspliceosomal complexInterproscan
GO:0005682
all species →
Cellular ComponentU5 snRNPInterproscan
GO:0030619
all species →
Molecular FunctionU1 snRNA bindingInterproscan
GO:0030620
all species →
Molecular FunctionU2 snRNA bindingInterproscan
GO:0030623
all species →
Molecular FunctionU5 snRNA bindingInterproscan
GO:0071013
all species →
Cellular Componentcatalytic step 2 spliceosomeInterproscan
GO:0097157
all species →
Molecular Functionpre-mRNA intronic bindingInterproscan
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan
GO:0008233
all species →
Molecular Functionpeptidase activityInterproscan
GO:0008237
all species →
Molecular Functionmetallopeptidase activityInterproscan
GO:0003723
all species →
Molecular FunctionRNA bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K12856PRPF8, PRP8; pre-mRNA-processing factor 8-Spliceosomeko03041deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_001633987.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
48TPM > 0
16Conditions
43.1Max TPM
22.8Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 3 24.26 28.41
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 16.64 24.21
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 14.72 15.27
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 20.54 26.08
whole 6 week old aboral regenerate · regenerate uncut 3 3 13.72 15.29
whole 6 week old aboral regenerate · regenerate 4hpa 3 3 23.30 27.10
whole 6 week old aboral regenerate · regenerate 120hpa 3 3 25.06 30.20
whole 6 week old aboral regenerate · regenerate 36hpa 3 3 24.63 28.10
whole 6 week old aboral regenerate · regenerate 24hpa 3 3 23.86 27.87
whole 6 week old aboral regenerate · regenerate 20hpa 3 3 23.43 26.00
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 18.48 20.96
whole 6 week old aboral regenerate · regenerate 72hpa 3 3 32.60 43.14
whole 6 week old aboral regenerate · regenerate 60hpa 3 3 28.67 34.81
whole 6 week old aboral regenerate · regenerate 48hpa 3 3 32.81 41.79
whole 6 week old aboral regenerate · regenerate 8hpa 3 3 20.43 21.70
whole 6 week old aboral regenerate · regenerate 12hpa 3 3 21.14 28.23

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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