Gene detail

Detailed information of XP_001634274.2 in Nematostella vectensis

Genomic Location: NC_064035.1:11832618...11841159
NR annotation: XP_001634274.2, DNA polymerase eta isoform X1 [Nematostella vectensis]
Species abbreviation NVECT · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

LOC5514019

ATGGCTAGCGATGAAAGAGTGATCGCCCTGGTCGACATGGACTGCTTTTATGTGCAGGTTGAACAGCGGCGATGCCCCGAGTTGAAGGGCAAACCTTGTGCAGTTGTCCAGTATAACGCGTGGAAGGGTGGAGGGATAATTGCTGTTAGCTACGAGGCTCGTGCTTGTGGGGTGACTAGAAACATGCGGGGTGATGAGGCCAAACAAAAGTGTCCGGACATTGCTCTTGTGCAGGTCCCTGTGCTGCGAGGAAAGGCAAACCTAGCTCACTACCGGGATGCTGGTGCTGAAGTGCTGGAAGTCCTGACCACATACTGTGATAATTGTGAGAGGGCAAGTGTTGACGAAGCTTACCTAGACCTCACAAATTCTGCTCAAAAAAAACTTAGTGTTATGACAGTTCCAGAAATAGCTGAGGAGGTTTGGAGAACAACGGCAATAGAGGGCCTCTCTTCAAAGGGTTCTGATACAACAATCAGTGATGAGCTACAAAAAGAATGGTTGAGTCAGCTGGAAGCCAGCCCTTACCTTAGAAACTTAGCAGCTGGTGCTGTAATAGCCGCTGAAATGAGGCATGCAGTCTTGGAAAAAACAGGTTTTACCTGTTCTGCAGGTGTAGCAACAAATAAGGTTCTAGCAAAGCTATGCTGTGGTCTCAACAAGCCTGATAAACAAACTCTACTTCCTCATTCTGCAGTTACTAATTTGTTCAAGACTATGCCCTTACGGAAAGTGAGACATTTGGGGGGTAAACTTGGCAGCCAGCTGCATTCAGAGCTGAATGTGGAATTCATGGGTGATTTATTGCAATTCAAGATAAATGACCTCAAAGCACAGTTTGGCAGTAAGAACGGCGAGCTGCTTTATAATTTGTGTAGAGGAATTGATAATGAGCCTGTACGAGCCCGTCAACTTCCCAAGTCAGTCAGTTGTGGCAAGAATTTTCCAGGAAAAACAAAGCTATCGACATGCCAACAGGTTAAGTTCTGGATGGAACAGCTAGTTGAAGAACTTCATGAACGGCTCATCAGAGAAGTAGAAGTGAATGATCGTCAAGGGACCCTTTTGACCGTTGGTCTACGGACAGAAGATGCTCCTGCGCGTTCCCGACAGTGTCCACTACAGAGCCCTGACAAGAGTTGGCTGAACAAGCGGATCTATGAGGTCTTACTCTCGTTTAAGACAAACAAGGAGGACAGTGATAAGTGGGAACCAGCTATTACAAACCTCTACCTGGGAGGCAGCAAGTTTGTCGAGGCGCCGAGTGCGTCTTCTACCCCCGCCATTCGCACCTTCTTCTCGCCGGCGGTAAGCGCCAAAGAGACTTTTGAGTCTGACAACTCAGGGCAATATCCTGGAAACATCGAGCCTCGTCAGAGCCTTGTTAACTCGGAGATTACAGCTAGTGAGGCGGCCCAGAGCGAATGTAAGGTCTCGCCTGTTCGAGGTTCTATGGACGCTTTTGTCACCAAAATGTCTGGCCCTTCAGACCCTTGCAAGAATACAAATGATTCTAGTCGGCTGGATTGTGAACCAATGCCCGCTACTAAATCTTCCCTCAGTCCGCTTAAATCTAGAACTGGAATTTGGCGATACATGAGATTGCCGAATTTGGAAAACGAACAAAATCAGGGTGACAAATATAGGGCAAGCGAAGAGGTAAGGACCATCGCGCAATCCAAGCCATTGTGCGATTCCGGGAAATATAATTGTTCTGATTCCGAGACATTGAAAACCTCGGAAAATTCGGACCGAGGTGAAGTTGGCACATTTTCTGGCAGTGTTGCTACGGCTTTTCAACACAGCGACTCTGACTATATGCAGTGTGATACATGCAAGGAAATGGTGTCCGCGTGGGACTTGCCCGAGCACCTAGACTTCCACTTCGCGGAACAGCTACAACGCGGAGATAATATTTCCCAGCATGCATCTCCGCCGAGGAAGAAACAGAAAACAGCGGCATTAAACATTAAAACATTTTTCGATTCCTGA

Transcript

rna-XM_001634224.3

GTGGTGAAAGTGGAAATTAGCGGCATAGTCAAAAGAAAATGGATGCCACTAGGTCATGGAACTCTCTCTGATCTGTGTAGTTTGTACTTAAGATAAGCAATTGTACGATGGCTAGCGATGAAAGAGTGATCGCCCTGGTCGACATGGACTGCTTTTATGTGCAGGTTGAACAGCGGCGATGCCCCGAGTTGAAGGGCAAACCTTGTGCAGTTGTCCAGTATAACGCGTGGAAGGGTGGAGGGATAATTGCTGTTAGCTACGAGGCTCGTGCTTGTGGGGTGACTAGAAACATGCGGGGTGATGAGGCCAAACAAAAGTGTCCGGACATTGCTCTTGTGCAGGTCCCTGTGCTGCGAGGAAAGGCAAACCTAGCTCACTACCGGGATGCTGGTGCTGAAGTGCTGGAAGTCCTGACCACATACTGTGATAATTGTGAGAGGGCAAGTGTTGACGAAGCTTACCTAGACCTCACAAATTCTGCTCAAAAaaaaCTTAGTGTTATGACAGTTCCAGAAATAGCTGAGGAGGTTTGGAGAACAACGGCAATAGAGGGCCTCTCTTCAAAGGGTTCTGATACAACAATCAGTGATGAGCTACAAAAAGAATGGTTGAGTCAGCTGGAAGCCAGCCCTTACCTTAGAAACTTAGCAGCTGGTGCTGTAATAGCCGCTGAAATGAGGCATGCAGTCTTGGAAAAAACAGGTTTTACCTGTTCTGCAGGTGTAGCAACAAATAAGGTTCTAGCAAAGCTATGCTGTGGTCTCAACAAGCCTGATAAACAAACTCTACTTCCTCATTCTGCAGTTACTAATTTGTTCAAGACTATGCCCTTACGGAAAGTGAGACATTTGGGGGGTAAACTTGGCAGCCAGCTGCATTCAGAGCTGAATGTGGAATTCATGGGTGATTTATTGCAATTCAAGATAAATGACCTCAAAGCACAGTTTGGCAGTAAGAACGGCGAGCTGCTTTATAATTTGTGTAGAGGAATTGATAATGAGCCTGTACGAGCCCGTCAACTTCCCAAGTCAGTCAGTTGTGGCAAGAATTTTCCAGGAAAAACAAAGCTATCGACATGCCAACAGGTTAAGTTCTGGATGGAACAGCTAGTTGAAGAACTTCATGAACGGCTCATCAGAGAAGTAGAAGTGAATGATCGTCAAGGGACCCTTTTGACCGTTGGTCTACGGACAGAAGATGCTCCTGCGCGTTCCCGACAGTGTCCACTACAGAGCCCTGACAAGAGTTGGCTGAACAAGCGGATCTATGAGGTCTTACTCTCGTTTAAGACAAACAAGGAGGACAGTGATAAGTGGGAACCAGCTATTACAAACCTCTACCTGGGAGGCAGCAAGTTTGTCGAGGCGCCGAGTGCGTCTTCTACCCCCGCCATTCGCACCTTCTTCTCGCCGGCGGTAAGCGCCAAAGAGACTTTTGAGTCTGACAACTCAGGGCAATATCCTGGAAACATCGAGCCTCGTCAGAGCCTTGTTAACTCGGAGATTACAGCTAGTGAGGCGGCCCAGAGCGAATGTAAGGTCTCGCCTGTTCGAGGTTCTATGGACGCTTTTGTCACCAAAATGTCTGGCCCTTCAGACCCTTGCAAGAATACAAATGATTCTAGTCGGCTGGATTGTGAACCAATGCCCGCTACTAAATCTTCCCTCAGTCCGCTTAAATCTAGAACTGGAATTTGGCGATACATGAGATTGCCGAATTTGGAAAACGAACAAAATCAGGGTGACAAATATAGGGCAAGCGAAGAGGTAAGGACCATCGCGCAATCCAAGCCATTGTGCGATTCCGGGAAATATAATTGTTCTGATTCCGAGACATTGAAAACCTCGGAAAATTCGGACCGAGGTGAAGTTGGCACATTTTCTGGCAGTGTTGCTACGGCTTTTCAACACAGCGACTCTGACTATATGCAGTGTGATACATGCAAGGAAATGGTGTCCGCGTGGGACTTGCCCGAGCACCTAGACTTCCACTTCGCGGAACAGCTACAACGCGGAGATAATATTTCCCAGCATGCATCTCCGCCGAGGAAGAAACAGAAAACAGCGGCATTAAAcattaaaacatttttcgatTCCTGATGGCATCGAATACGAGTATTATTATGTACTGATTTTTTGTatgaataattaaaaataatttaaaattc

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9JJN0	DNA polymerase eta OS=Mus musculus OX=10090 GN=Polh PE=1 SV=1
Q9Y253	DNA polymerase eta OS=Homo sapiens OX=9606 GN=POLH PE=1 SV=1
Q8H2D5	DNA polymerase eta OS=Arabidopsis thaliana OX=3702 GN=POLH PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005836 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00817 all species →	IMS	impB/mucB/samB family	Family	Interproscan
PF21704 all species →	POLH-Rev1_HhH	DNApol eta/Rev1, HhH motif	Motif	Interproscan
PF18439 all species →	zf_UBZ	Ubiquitin-Binding Zinc Finger	Domain	Interproscan
PF11799 all species →	IMS_C	impB/mucB/samB family C-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036775 all species →	Homologous_superfamily	DNA polymerase, Y-family, little finger domain superfamily	Interproscan
IPR041298 all species →	Domain	DNA polymerase eta, ubiquitin-binding zinc finger	Interproscan
IPR043502 all species →	Homologous_superfamily	DNA/RNA polymerase superfamily	Interproscan
IPR001126 all species →	Domain	UmuC domain	Interproscan
IPR043128 all species →	Homologous_superfamily	Reverse transcriptase/Diguanylate cyclase domain	Interproscan
IPR052230 all species →	Family	DNA polymerase eta	Interproscan
IPR017961 all species →	Domain	DNA polymerase, Y-family, little finger domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45873 all species →	DNA POLYMERASE ETA	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003684 all species →	Molecular Function	damaged DNA binding	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0003887 all species →	Molecular Function	DNA-directed DNA polymerase activity	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005657 all species →	Cellular Component	replication fork	Interproscan
GO:0009314 all species →	Biological Process	response to radiation	Interproscan
GO:0035861 all species →	Cellular Component	site of double-strand break	Interproscan
GO:0042276 all species →	Biological Process	error-prone translesion synthesis	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K03509	POLH; DNA polymerase eta	EC:2.7.7.7	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.