Gene detail

Detailed information of XP_001636449.2 in Nematostella vectensis

Genomic Location: NC_064034.1:1985896...1995285
NR annotation: XP_001636449.2, serine/threonine-protein kinase TBK1 isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

LOC5516342

ATGGAGACTCGTAGCAGTTCAAACTATATCTGGAATCTGAAAAGTGTCCTTGGCCAAGGAGCTACAGGGGCAGTGTACACAGGTCGGCATAAGAAAAGTGGAGATGTAGTTGCTGTAAAGACATCTAACCACTTGGGGATGATGAGACCTCTAGAAGTGCGGAAAAGAGAGTTTGATGTTCTGAGCAAACTTGACCATGAGAATATCGTCAAAATCTTCGCATCTGAGACCGAGTTGCGATCACAAAATGAGATAATTGTGATGGAATTATGTTCTGGTGGAAGCTTGTTTACTATGCTTGAGCACCCAAGCAACGCTTATGGTCTCTCTGAACAAGATTGCATTGCTGTCATTCGGGATGTTGTCGCTGGAATGAAGCATCTCCATGATAATGGCATTGTCCATAGGGATCTGAAACCTGGGAACATTATGAGGGTGTACCGAGATGACGGCAGCTGTGTGTACAAGTTGACAGACTTTGGTGCTGCACGAGAATTGATGGAATCTGATCAGTTTGTGTCTATCTATGGAACAGAGGAGTACCTGCATCCTGACTTGTATGAGCGTGGCGTGCTGCGTAAAGCAACCGGAAAGACATTTGGAGCCCAGGTTGACCTCTGGAGCATTGGAGTGACATTTTACCACATCGCCACTGGGAGGCTCCCCTTCAGACCATTTGGTGGACGACAAAACAAAGACACAATGTATCACATCACAACACGGAAAGCATCTGGGATGATCGCTGGTGTGCAAAAGAGTGAGGGAGGGGAGGTAGAGTGGACAGACAAGCTACCGGACCACACCTGTTTATCACAAGGGTTCCGTAACCTGTTAACACCGTTACTTGCTGGAGTGCTAGAGTCAGATCCAGCTAAAATGATGTCATTTGATCAGTTTTTTGCCTACGTCCAGGACATGGTATCAAGGAAGGTTTTAGATGTTTATTGTGTATCGTCCAGTCAGTTCCATAAAATATACATCAGAAGGACAGAGATGCTCAACAGATTCAAGCAGATGGTCACTGAGCAGACAAGTGTACCATGTGATCAACAAGAGCTCTTCTATGAGTTCCAGTACTTCCAGCCTCCCGACATGTGCCCTGCGGCTGATTTCCCAAACACGTCCAGAGATCGACCTGTTATAATGATTGGTGGAGAGCAACTTGCGCCGGACAAACTCGTCAACTTGGCAATACCAAAAATAACTGAGCTTCCTCCAGAATGGACTCTTGAGGGTGATGCTGCTGTCTCGAAGATCATGGCAAATTGTGCGTATTCTTGCGAGCACTCAGTGGCCGTGTACAGTGACAGCGTCAAAGCCATGACCGACATGATCCACACTTTAGGGGGGACTTCATCTACAAATAAGATGATGGCATTTAGAACAATATATTCAGAGCTTCATGAGTTGAGAACCCTCGCTGCTGGTGCAAAAGTAATTGCTTTGACAGCAACAGCAACACTGCCAACAAAAGAAACAATTACAGATGTACTTAGAATGCAAGACGTCATAGAAATAAATGAAAATCCCAATAAGGAGAACATTACCTATATTGTCAAGTATTTAAGTAACTCAATGGATGCTAAAGAAAGTTTTGAATGGTTGGTGAATGAAATCAATGAAAGAAAAGATGGTGGAGATAAAACAATCATATACTGCCAAACAATAAAACAGTGTTCTTTGGTGTATGGCACCCTGAGATCTATGTTGATAGAGTTGGTTGCTAATGGAAAACCAAAACTTGAAATGCTTCATTCCTGTACTCCAAAAGAAAATAAGGATGCAATATTAGAGTCATTCAAAAGACTGGATGGTCATGTGCAAGTCTTGGTGGCAACCATAGCATTCGGCATGGGAATAGACTGTAAAGGTGTCCACCGCACAATACACTTTGGCCCCTCAAAAAACTGTGAGGCCTTTATCCAAGAGACTGGTCGTGCTGGAAGAGATTGGAAGTCTAGTTTTTCTTATCTTTTGTACAAAGGCATTATGCTGAATCATGTGGAAAGGGACATAAAAGAATATGTCAAAGCTACAACCTGCAGGAGACAGATGCTTATGAAACATTTTAGCAAGAACCATATTGTATTTTCTGGAGACCTCCATGCTTGCTGTGATAATTGTGCTAAAGCTTGTGAATGTGTTAGTGAAAATTGTGAAAGTTACACTGATTTCATGGTTACGGAGACAGGTATTGCATCAGAAGAGAAAAGGCGTTCTGTTAGTGAAGACCAGAAAAAAGAACTCTCAGGATTACTCAAAAAGTACCACAAGAAACTATTAATGGATCTGGTACGAAAGTCAGCACATGACATGGTCCAAAGTCTGATTAGCATGAATACTCTTCTGGGGTTTGGAGAAACACAAATCGACCTGGTGCTAGAAACTGTGAAACTTTATTTTCTTTTGAGCATGTCACAGATAAGATTGAAATATGGAACATCTGTCATGCAAGAGAAATAG

Transcript

rna-XM_001636399.3

ACACAAACTACTTCACTTGGTTTTGAGAATCCAAGAAAGTCTAAAATGGAGACTCGTAGCAGTTCAAACTATATCTGGAATCTGAAAAGTGTCCTTGGCCAAGGAGCTACAGGGGCAGTGTACACAGGTCGGCATAAGAAAAGTGGAGATGTAGTTGCTGTAAAGACATCTAACCACTTGGGGATGATGAGACCTCTAGAAGTGCGGAAAAGAGAGTTTGATGTTCTGAGCAAACTTGACCATGAGAATATCGTCAAAATCTTCGCATCTGAGACCGAGTTGCGATCACAAAATGAGATAATTGTGATGGAATTATGTTCTGGTGGAAGCTTGTTTACTATGCTTGAGCACCCAAGCAACGCTTATGGTCTCTCTGAACAAGATTGCATTGCTGTCATTCGGGATGTTGTCGCTGGAATGAAGCATCTCCATGATAATGGCATTGTCCATAGGGATCTGAAACCTGGGAACATTATGAGGGTGTACCGAGATGACGGCAGCTGTGTGTACAAGTTGACAGACTTTGGTGCTGCACGAGAATTGATGGAATCTGATCAGTTTGTGTCTATCTATGGAACAGAGGAGTACCTGCATCCTGACTTGTATGAGCGTGGCGTGCTGCGTAAAGCAACCGGAAAGACATTTGGAGCCCAGGTTGACCTCTGGAGCATTGGAGTGACATTTTACCACATCGCCACTGGGAGGCTCCCCTTCAGACCATTTGGTGGACGACAAAACAAAGACACAATGTATCACATCACAACACGGAAAGCATCTGGGATGATCGCTGGTGTGCAAAAGAGTGAGGGAGGGGAGGTAGAGTGGACAGACAAGCTACCGGACCACACCTGTTTATCACAAGGGTTCCGTAACCTGTTAACACCGTTACTTGCTGGAGTGCTAGAGTCAGATCCAGCTAAAATGATGTCATTTGATCAGTTTTTTGCCTACGTCCAGGACATGGTATCAAGGAAGgtTTTAGATGTTTATTGTGTATCGTCCAGTCAGTTCCATAAAATATACATCAGAAGGACAGAGATGCTCAACAGATTCAAGCAGATGGTCACTGAGCAGACAAGTGTACCATGTGATCAACAAGAGCTCTTCTATGAGTTCCAGTACTTCCAGCCTCCCGACATGTGCCCTGCGGCTGATTTCCCAAACACGTCCAGAGATCGACCTGTTATAATGATTGGTGGAGAGCAACTTGCGCCGGACAAACTCGTCAACTTGGCAATACCAAAAATAACTGAGCTTCCTCCAGAATGGACTCTTGAGGGTGATGCTGCTGTCTCGAAGATCATGGCAAATTGTGCGTATTCTTGCGAGCACTCAGTGGCCGTGTACAGTGACAGCGTCAAAGCCATGACCGACATGATCCACACTTTAGGGGGGACTTCATCTACAAATAAGATGATGGCATTTAGAACAATATATTCAGAGCTTCATGAGTTGAGAACCCTCGCTGCTGGTGCAAAAGTAATTGCTTtgacagcaacagcaacactgccaacaaaagaaacaattaCAGATGTACTTAGAATGCAAGACGTCAtagaaataaatgaaaatccCAATAAGGAGAACATTACCTATATTGTCAAGTATTTAAGTAACTCAATGGATGCTAAAGAAAGTTTTGAATGGTTGGTGAATGAAATCAATGAAAGAAAAGATGGTGGAGATAAAACAATCATATACTGCCAAACAATAAAACAGTGTTCTTTGGTGTATGGCACCCTGAGATCTATGTTGATAGAGTTGGTTGCTAATGGAAAACCAAAACTTGAAATGCTTCATTCCTGTActccaaaagaaaataaggatGCAATATTAGAGTCATTCAAAAGACTGGATGGTCATGTGCAAGTCTTGGTGGCAACCATAGCATTCGGCATGGGAATAGACTGTAAAGGTGTCCACCGCACAATACACTTTGGCCCCTCAAAAAACTGTGAGGCCTTTATCCAAGAGACTGGTCGTGCTGGAAGAGATTGGAAGTCTAGTTTTTCTTATCTTTTGTACAAAGGCATTATGCTGAATCATGTGGAAAGGGACATAAAAGAATATGTCAAAGCTACAACCTGCAGGAGACAGATGCTTATGAAACATTTTAGCAAGAACCATATTGTATTTTCTGGAGACCTCCATGCTTGCTGTGATAATTGTGCTAAAGCTTGTGAATGTGTTAGTGAAAATTGTGAAAGTTACACTGATTTCATGGTTACGGAGACAGGTATTGCATCAGAAGAGAAAAGGCGTTCTGTTAGTGAAGAccagaaaaaagaactctcaGGATTACTCAAAAAGTACCACAAGAAACTATTAATGGATCTGGTACGAAAGTCAGCACATGACATGGTCCAAAGTCTGATTAGCATGAATACTCTTCTGGGGTTTGGAGAAACACAAATCGACCTGGTGCTAGAAACTGTgaaactttattttcttttgagCATGTCACAGATAAGATTGAAATATGGAACATCTGTCATGCAAGAGAAATAGTTGTTATCCTTGCAGAAGTATTTAATGATATTGATGTATCTTGTGAGCATATGGTCGATATGAGACTGGGCACTAGCGATGATGAATTAGATGACGAAGTAATTGGAGAATGGGCTGCTCTAGCTGAGGACGAAGAGCTCTTTGCCTTGATGGCAGACAATTTATCTTGGTCTGCATTAGAGAGCACAGTAAATGAGTCAACCCACATGCAGTCTCCTGACTCTTCTGGCTTATCACCTGCTGCTCTGACTGCACTTACAAATCTAAGTATAGAGTAGAAAAAATGTATACCACCAGTAGAGGTATGACATGGCTTATGTTATTCTTGTCAGAGCTGGGTATTAAGTGAAGGAAAAAAGCAGAAAAATCTGTAACGCAACGTTTACATTTAAGCTTCATTGGCATATAACAAATTGCAATACAGACACTTAGAGCGGCAAAAACTTAACTGAACAGTAAGCGATTCTGGAGGTGACTTTGAAAACTCAAATTAATTTTATAGAGTGTGTATGACCTCAACATTAGCTGTTTTGGCCCACAGCACGCTAATTGCTCTACTCTTTAGTTTGCATTGCAAACAAGAAAAGACCCAAGAGGACAGTGTCTAAACAGTACTTCCACATTTTCTCTGCAGTTTAGAGCATAGTAAAGACTTAATTTTTCCCACGATGCTGTGTGGCACACTTAATGAGCTTTTATTATAAATTCTTTAAATTTGGAGTTGTTAAAGTTGTACTGTATACACAATCAGACAATATCTTATGTTTGTAAAAGTATTCAGTAGTCTATTATTCGTAGTCCCACTAGATGTGATGATATACTAATGTCTACTAATGAGAGTAAAACATGTCAACCAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9UHD2	Serine/threonine-protein kinase TBK1 OS=Homo sapiens OX=9606 GN=TBK1 PE=1 SV=1
Q9WUN2	Serine/threonine-protein kinase TBK1 OS=Mus musculus OX=10090 GN=Tbk1 PE=1 SV=1
Q6DFJ6	Serine/threonine-protein kinase TBK1 OS=Xenopus laevis OX=8355 GN=tbk1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003057 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF18396 all species →	TBK1_ULD	TANK binding kinase 1 ubiquitin-like domain	Domain	Interproscan
PF00271 all species →	Helicase_C	Helicase conserved C-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR001763 all species →	Domain	Rhodanese-like domain	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR041087 all species →	Domain	TANK binding kinase 1, ubiquitin-like domain	Interproscan
IPR001650 all species →	Domain	Helicase, C-terminal domain-like	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR051180 all species →	Family	Inhibitor of nuclear factor kappa-B kinase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22969 all species →	IKB KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0018105 all species →	Biological Process	peptidyl-serine phosphorylation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for XP_001636449.2.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.