Gene detail

Detailed information of XP_001637354.2 in Nematostella vectensis

Genomic Location: NC_064042.1:4477587...4487173
NR annotation: XP_001637354.2, amyloid-beta precursor protein [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_001637304.3

AATCACCCGCGGTTGTCACGTGACTGATTTAGAACAAGCGCAACTCAAACTTTAGGTCcgccatttttgttttctaccATAGGAACTTTTCTGGCGTCTTTCACGAGAAATATGAATTGGATCGTAACATTGACGATCTTTTCGTCAGTGTGTTTCTTTAAGGTGCTATGTGAAGATAGTGCCGAATCTCTACCCAAACATGAGCCTCTTGTAGCCATGTGGTGTGGCAAGGTCAACCAGCACATGGACATCAACACAGGGGAATGGGCGACAGATGAGAATGGACACTCCATGTGCTCTACAAGCACCAAACAAGTGCTGAAGTACTGCCAACATGTGTACCCCAAGCTCAATGTAAGCAATGTTGTGGAAGCCAACATGAATGTGACTATCAAGACTTGGTGTGATCCTAAGAATGTCAACTGCAATGCCACTAAGACTGTCTtgccatacagatgccttgTTGGCAAGTTCGAAGCTGATGCTCTTCTGGTGCCACCCGGCTGTCGCTTTCAGCATCTTCACCCCGGAAGCGAGTGCAAGTCCCATGACTTCTGGAAGATTAAGGCAGAGGAGAAGTGCAAGGATCAAGACGCCAATCTCAGGTATTATGGCGTCCTCCTACCATGCAACACTGGTCTGTTCACTGGTGTTGAGTTTGTATGCTGCCCGGTCAAGAAGCCAGATAACAAGCTTCCTTTCGAGAAGGTTGTTCCTGCCATTGAGGTTGAAGTGGCAACACCCATCCCGACCACTGCCCCGCCCGCCTCGATTATTGACAAGCTGGAGGCAGAGGTCAAGGAGTATGACAAGAAGATCATCCCTGCTTTGTTTGGGTGCAACCTGACGAAGTACCGGGAGGAGCGCAAAAAGCTGAATGAGCAGCACCGCGTCAACATGAAGCAAGTTATCAAGCAATGGGAGGACGCAGAGAAGCGCTACAACATCCTCCACAAGGACGAACCCAAGCAGGCTGAGCAGATGATGGCGGGCGTAATGGCGCGCTTCAAGGAGACCATCTCCACCCTTGAGCAGCAAGCCAAGCTGGAGCGCCAGCGCCTCCACGAGGAGCATCATCAGTGTCTGCAGATCCACATCAACGAGAAGCGCCACAAGACCATCAAGACTTTCCTCCGCGAGCTCAGGCGGGAGATCAAGAACCCAGACAAGATCCTGGCCGCCATGCGAATGTTCACGAACATTTGCAACGAGGACCGCGTTCACAACCTCCGTTACTTTAAAATCGCGAGCAAGCACAACCCAGAGATGACCGAGGAGATGCGTGCTAACCTCAAGGAGCATCTGGACAAGATTAACCAGCGTATGAACGACACCATGACCCTGCTGTACAACATGCCCAAGATCATGAGGAAGTTCGCCTTTGAGCTGCCCAACTGGGCCCCCAAGATCCCTCTCCCGACTGAACCACCAACTGAGAAGATGACCGAGGCCCCGACCACTCCATCCGCGGTCCACGGCGAGGAAGACGAGAACAAACCTTACCGCAAGCACGAGGAGCGCGAGCGACACCACGGTCGCCACGGCAACAGCAAGAAACACCGCAAACACGACGAAGAGGACGAGCCCGAGAATGAGCGCGACTTCTTCGGCGAGCCTCGCTCTCCCGCCACATTCGCAGCCGTGATTGGTCTAAGCTGCGGCGCCCTCGTCATCATGATCGTCATCATCGTTGCCATGGCGATGAGGAGGTCACGTGGCAGCAGCGCTACCAAGACGGTTCTTGTTGACCCCGACGCGGACGGGAACTCTGAGAAGCAGCGGCTGACGGATCTTCAAGAGAACGGGTACGAGAACCCTACCTACAAGTTCTACGACTATTAGACTAGCGTGCCGCCACCTTAACTGCACTCTCTTTATGGGCAGGTTGATAGCGCTACAGTTAATAAGACTGGCGAGAAATGCGAACGGGAGCGTTATTGTGAAGGGCACGGGAATGGGATTTTTTGGTAAATTATCGAAGGAAGGTAAAGGGTTGACTAGCGCTAAAGACCAAGGGCTTTTCATGTACCCCTAACTTTTATAAGACTCGGTCCCCTGACCATATGCCAGTTCGCTAGGATCTTCTAAACGCTCTTGGGTATCAAGGTCTTCTGATTCTTGACGAATTGAGAAAAATGTTATACGCGTGGAGAGTGTAGCATTTATAAATCTTTCTATCCGCCCATTGCTCTAAAAGGAAATGTAGAAATAGCACAGGCCGTGGCACGGGCTTAACAAGATATATATACTCATTCTTTGGTTTGAATTTTCGTATTTGTTTTTACTAAGGGCTTACCATTAGGTGTAGTGTTTGTAGCAGTGAGGCTTTTCGACGCCATCTACTACAATCTTATCTAAGTAAAGGTTATTTAAGTAGCGTTAGTGAGACGTGTACATGTATAGATTAAGAACCTTTTAAAAAAGGGGACGATGCATTTATCTTTTACTATGGTTTATTCATCAGCAACTAATTATATTATGCAAAGGAACGCTTTTTATACGAGAAGAAAACCACGCAAAGTTTCAACAGCGCTACGCGAAGATACCAAAATATCGTAACACTAACATTCTCGGGTGCCGGTTTATTGTGTTGGCTAGCGTGGACTCCTAGTTGCGAAGGCGTTCAATCTTTCAAGTTCTTAGTGTACTCAACTGCTATAATACACCAGTGCACTGCAGCTCTAGCAGATTCAGTTATCCGCCAGTTGACTAAGGGcgcgtcttttttttttctatcattctggaatgggaatggttggtagagaatgttcagaatggcattcaAGTCATTCTGCTTCAGGTAGCAAaatgggtggaatggcctttATCCCATTCCGAAATGGGAACGTGCTATAAACAAaacgcgcgctttttctattctaataaTTCTCATTCCGGtatcacgagtaaaaaaaccCGCCCTAAGACTGGTCTAGTAGGGTGGTGAGGAACTACGGCTTTCCCTTTCAACCTTTTGActccaccgtcatcatcactaacatgatcatcattatgatatcatcatcattataagcATTTGTCAGCATCATGtttacatcatcatcatccaagCTTGTAATCATGCGTTCCATTGTAACACGTGACCGGAAGTTGATTGATATTTAACCCCATCACGACAAGCCCGTTTTGGCAGACGCAACTTACTGTTTTCGGTAAgatttagttttatttaaatttgTAACTTAGGCTGCTGCTGCAATAAAAATGTCTTGAAAATA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q95241	Amyloid-beta precursor protein OS=Saimiri sciureus OX=9521 GN=APP PE=2 SV=1
Q60495	Amyloid-beta precursor protein OS=Cavia porcellus OX=10141 GN=APP PE=1 SV=2
O93279	Amyloid-beta A4 protein OS=Takifugu rubripes OX=31033 GN=app PE=3 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006067 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02177 all species →	APP_N	Amyloid A4 N-terminal heparin-binding	Domain	Interproscan
PF12924 all species →	APP_Cu_bd	Copper-binding of amyloid precursor, CuBD	Domain	Interproscan
PF10515 all species →	APP_amyloid	Beta-amyloid precursor protein C-terminus	Family	Interproscan
PF12925 all species →	APP_E2	E2 domain of amyloid precursor protein	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR008154 all species →	Domain	Amyloidogenic glycoprotein, extracellular	Interproscan
IPR015849 all species →	Domain	Amyloidogenic glycoprotein, heparin-binding	Interproscan
IPR036176 all species →	Homologous_superfamily	E2 domain superfamily	Interproscan
IPR008155 all species →	Family	Amyloidogenic glycoprotein	Interproscan
IPR011178 all species →	Domain	Amyloidogenic glycoprotein, copper-binding	Interproscan
IPR036454 all species →	Homologous_superfamily	Amyloidogenic glycoprotein, heparin-binding domain superfamily	Interproscan
IPR019744 all species →	Conserved_site	Amyloidogenic glycoprotein, copper-binding domain conserved site	Interproscan
IPR019543 all species →	Domain	Beta-amyloid precursor protein C-terminal	Interproscan
IPR024329 all species →	Domain	Amyloidogenic glycoprotein, E2 domain	Interproscan
IPR036669 all species →	Homologous_superfamily	Amyloidogenic glycoprotein, copper-binding domain superfamily	Interproscan
IPR019745 all species →	Conserved_site	Amyloidogenic glycoprotein, intracellular domain, conserved site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23103 all species →	ALZHEIMER'S DISEASE BETA-AMYLOID RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0008201 all species →	Molecular Function	heparin binding	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0046914 all species →	Molecular Function	transition metal ion binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for XP_001637354.2.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.