Gene detail

Detailed information of XP_001639094.2 in Nematostella vectensis

Genomic Location: NC_064043.1:10485009...10489447
NR annotation: XP_001639094.2, protection of telomeres protein 1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

LOC5519196

ATGGCGGAAAAATTCAAACATGAAGTTGTTACACTAAAAAATATCAACGAGCTCCAAAAACTGAAGGATTGCCATTTCGAATCAATCCGTGAGATCAACGAACAGTGTGCGAAGGACCCAGAACTGCATATAAAAGGTGTGATAAAAACTGCATATGCCACATTTGAAACCAGGAAAACCTTCACGAGAAAGCTTGTTATAAAGAACGAAGTATGTCAAGATATCCTTGATACTATAAACCTATTTCTCAAAGGAGATGTTGCAAAGAAGTGCAATTTCCTCCAGCCAAATGACACTATAGTGATAAAGGGGTTTACCCTGGAGAAAACCAATTCTTCGGGTCATCCCTTTCGGATCTTGCTAGATTCCAACAAAAATGATGTAACAATCTTGGCTATCCCACATAAACAAAAAGTGCCAAGTACTACCATGGAAAATGCGACAGTAAACACAAAGCCAAGTGAGACATCAGTTAAAGGTGCATGTGGCCGAAACTCCAAGCAAAGTAGCATGAGAGGTGGAGGTTTCTTTGTTTCAAGTTTTGATGCACTAAGTACTAATTCCCAAAATAGCAACTTGAATGCACAGTCAGGCAAGGAATCCTACACAAAGCTTGCTGAGCTAAAGCATGGTGCTATCAAGAACTTCTATGGGCTTGTGAAGTTCTGTAAAGTGTCCAAGACAAGAAGAGGGGAGTATGTCGCTGCCATAAGTTTGGTTGACGAGTCACTATCATCACTAGAGGAAAGCTTTAAGTGCAATATTTTCACCAAGAGTGTTGAACACCTTCCATTGGTGCATTCTGTTGGGGACATTCTACGTTTAGATGGTGTGAGTCTGGTTAGATTCAATGGAGTGACACAAGGGACAGTATCAAGCTTTAAGTCAGATTCATTTTCATGGTTGTCATTTAATGGTTCTTATGACGCCCCAGTTCTTCCCATGGCATCATCCTCAGCAAAGTACCATATGGATGATGATGACATCACAAGAGTCAGGGAACTCAAAGATCTTGCTAAAACTGCACCCAGAATTAACCCAAGCAGAACTCTCCAAACCATCAGTGGCTTAGATCCTTCAACACAGTTTGTCAATCTGGCTTGTCAGGTTCTTGCCCTATGGAAAGATCCTGCCTTAAACTTCCTTGTGCTGCAAGTCTGGGATGGGACGACACCACGGTATGGTTGCGATGTTGAGGTTGATGATCATAGTAGGTGGGTTATGGACAGAAAGATCTCGGAGCAGGCTGGTGGAATGGCTATTCCAGTGTGCCTCTATGATGAGCATTCCACTGGACCAGCAGCAGATCTTAACCCTGGTGACTTTGTTATGTTGGCCAATGTGAGGCTGAAGGAAGTGGACAATGAGGAAAACGGGAAACCAAGAGTTGAGTGCATGATGCATAGTGATTGCATCAACGGCAGGGGAGTGTACATGCTCAAAGACACAGGATGGACTGACTGGTATCTCCAGAAACTAAAGGACAGTATCCAAAACTATCTGGACAACCACCCTCCACAGTCCCTCAGAGAAGAGATAGCAGAAGCTGTCAGTGATCTGCGAACCCAGCAGACTTCATGCACAGTGACCGATCACCCAAGGGTCCCATTTACCACATTATGGGATATCCACAACCAAGAAAAAGTGCCAAACAAGTACAAATGCAGAGTGAAGGCAATTTCCTTTATTCCTCCTCAGACCAAAGAGTTTGTGCAGCTGCACTGCAGCACATGTAAGAAACTAGCATCAAGAATTGGTGGGCCCTCTGGGTCCAATATTGATGATGACTGCGATGGCTTAGGAACACAGCATGATCGCGATGTAACTCCACATTCTTGCCCAGTTTGTGGCAACCCTTTCACAAGAACCTACCTTTTCTCGTTACTGTTAGCAGACAGGACAGATATGCTCATCGCGATGGTATTTGATGATGATGTGAAGCACTTTTTCCCCAACCTCCCCTCCCCTGAAGACTTCTTGGCAAGTGAGGAGCACCAGGATGGATTACATCATAGCCTCGTTTCCATGACACAAAACCCGGAGTGTAGCATTGACTTTGATAGCCAGTCGCTTGAGTCCAGGCCCTGGATGGAGTGCTGCGTCATGTCCTACCACAGTACCCCCGAAGATACTAGTAAGATAAGACGCTCTGTCAAGTATAGGATCTTTGGTACTACTTTAGTTTAA

Transcript

rna-XM_001639044.3

AATACCGAAGGCGCAGCACTCCAGAACTCCAAAAATGGCGGAAAAATTCAAACATGAAGTTGTTAcactaaaaaatatcaacGAGCTCCAAAAACTGAAGGATTGCCATTTCGAATCAATCCGTGAGATCAACGAACAGTGTGCGAAGGACCCAGAACTGCATATAAAAGGTGTGATAAAAACTGCATATGCCACATTTGAAACCAGGAAAACCTTCACGAGAAAGCTTGTTATAAAGAACGAAGTATGTCAAGATATCCTTGATACTATAAACCTATTTCTCAAAGGAGATGTTGCAAAGAAGTGCAATTTCCTCCAGCCAAATGACACTATAGTGATAAAGGGGTTTACCCTGGAGAAAACCAATTCTTCGGGTCATCCCTTTCGGATCTTGCTAGATTCCAACAAAAATGATGTAACAATCTTGGCTATCCCACATAAACAAAAAGTGCCAAGTACTACCATGGAAAATGCGACAGTAAACACAAAGCCAAGTGAGACATCAGTTAAAGGTGCATGTGGCCGAAACTCCAAGCAAAGTAGCATGAGAGGTGGAGGTTTCTTTGTTTCAAGTTTTGATGCACTAAGTACTAATTCCCAAAATAGCAACTTGAATGCACAGTCAGGCAAGGAATCCTACACAAAGCTTGCTGAGCTAAAGCATGGTGCTATCAAGAACTTCTATGGGCTTGTGAAGTTCTGTAAAGTGTCCAAGACAAGAAGAGGGGAGTATGTCGCTGCCATAAGTTTGGTTGACGAGTCACTATCATCACTAGAGGAAAGCTTTAAGTGCAATATTTTCACCAAGAGTGTTGAACACCTTCCATTGGTGCATTCTGTTGGGGACATTCTACGTTTAGATGGTGTGAGTCTGGTTAGATTCAATGGAGTGACACAAGGGACAGTATCAAGCTTTAAGTCAGATTCATTTTCATGGTTGTCATTTAATGGTTCTTATGACGCCCCAGTTCTTCCCATGGCATCATCCTCAGCAAAGTACCAtatggatgatgatgacatcACAAGAGTCAGGGAACTCAAAGATCTTGCTAAAACTGCACCCAGAATTAACCCAAGCAGAACTCTCCAAACCATCAGTGGCTTAGATCCTTCAACACAGTTTGTCAATCTGGCTTGTCAGGTTCTTGCCCTATGGAAAGATCCTGCCTTAAACTTCCTTGTGCTGCAAGTCTGGGATGGGACGACACCACGGTATGGTTGCGATGTTGAGGTTGATGATCATAGTAGGTGGGTTATGGACAGAAAGATCTCGGAGCAGGCTGGTGGAATGGCTATTCCAGTGTGCCTCTATGATGAGCATTCCACTGGACCAGCAGCAGATCTTAACCCTGGTGACTTTGTTATGTTGGCCAATGTGAGGCTGAAGGAAGTGGACAATGAGGAAAACGGGAAACCAAGAGTTGAGTGCATGATGCATAGTGATTGCATCAACGGCAGGGGAGTGTACATGCTCAAAGACACAGGATGGACTGACTGGTATCTCCAGAAACTAAAGGACAGTATCCAAAACTATCTGGACAACCACCCTCCACAGTCCCTCAGAGAAGAGATAGCAGAAGCTGTCAGTGATCTGCGAACCCAGCAGACTTCATGCACAGTGACCGATCACCCAAGGGTCCCATTTACCACATTATGGGATATCCACAACCAAGAAAAAGTGCCAAACAAGTACAAATGCAGAGTGAAGGCAATTTCCTTTATTCCTCCTCAGACCAAAGAGTTTGTGCAGCTGCACTGCAGCACATGTAAGAAACTAGCATCAAGAATTGGTGGGCCCTCTGGGTCCAATATTGATGATGACTGCGATGGCTTAGGAACACAGCATGATCGCGATGTAACTCCACATTCTTGCCCAGTTTGTGGCAACCCTTTCACAAGAACCTACCTTTTCTCGTTACTGTTAGCAGACAGGACAGATATGCTCATCGCGATGgtatttgatgatgatgtgaagCACTTTTTCCCcaacctcccctcccctgaagACTTCTTGGCAAGTGAGGAGCACCAGGATGGATTACATCATAGCCTCGTTTCCATGACACAAAACCCGGAGTGTAGCATTGACTTTGATAGCCAGTCGCTTGAGTCCAGGCCCTGGATGGAGTGCTGCGTCATGTCCTACCACAGTACCCCCGAAGATACTAGTAAGATAAGACGCTCTGTCAAGTATAGGATCTTTGGTACTACTTTAGTTTAAGGGTCGTATATTATAGAAAGAAACCcgatatcttttttttcag

Protein

UniProt (Swiss-Prot top hit)

No Swiss-Prot hit above the reporting threshold for this gene.

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002243 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02765 all species →	POT1	Telomeric single stranded DNA binding POT1/CDC13	Domain	Interproscan
PF16686 all species →	POT1PC	ssDNA-binding domain of telomere protection protein	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR011564 all species →	Domain	Telomeric single stranded DNA binding POT1/Cdc13	Interproscan
IPR012340 all species →	Homologous_superfamily	Nucleic acid-binding, OB-fold	Interproscan
IPR028389 all species →	Family	Protection of telomeres protein 1	Interproscan
IPR032042 all species →	Domain	Protection of telomeres protein 1, ssDNA-binding domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR14513 all species →	PROTECTION OF TELOMERES 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0000723 all species →	Biological Process	telomere maintenance	Interproscan
GO:0000781 all species →	Cellular Component	chromosome, telomeric region	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0000783 all species →	Cellular Component	nuclear telomere cap complex	Interproscan
GO:0010521 all species →	Molecular Function	telomerase inhibitor activity	Interproscan
GO:0016233 all species →	Biological Process	telomere capping	Interproscan
GO:0032210 all species →	Biological Process	regulation of telomere maintenance via telomerase	Interproscan
GO:0043047 all species →	Molecular Function	single-stranded telomeric DNA binding	Interproscan
GO:0051974 all species →	Biological Process	obsolete negative regulation of telomerase activity	Interproscan
GO:0098505 all species →	Molecular Function	G-rich strand telomeric DNA binding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11109	POT1; protection of telomeres protein 1	-	DNA replication proteins	ko03032	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_001639094.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

32TPM > 0

16Conditions

1.7Max TPM

0.6Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole 6 week old aboral regenerate · regenerate 96hpa	3	1	0.43	1.29
whole 6 week old aboral regenerate · regenerate 144hpa	3	3	0.81	1.20
whole 6 week old aboral regenerate · regenerate 0hpa	3	3	0.60	0.76
whole 6 week old aboral regenerate · regenerate 2hpa	3	2	0.56	0.89
whole 6 week old aboral regenerate · regenerate uncut	3	3	0.67	0.83
whole 6 week old aboral regenerate · regenerate 4hpa	3	1	0.22	0.67
whole 6 week old aboral regenerate · regenerate 120hpa	3	2	0.65	0.98
whole 6 week old aboral regenerate · regenerate 36hpa	3	2	0.58	1.01
whole 6 week old aboral regenerate · regenerate 24hpa	3	2	0.48	0.98
whole 6 week old aboral regenerate · regenerate 20hpa	3	2	0.41	0.72
whole 6 week old aboral regenerate · regenerate 16hpa	3	3	0.47	0.56
whole 6 week old aboral regenerate · regenerate 72hpa	3	2	0.80	1.37
whole 6 week old aboral regenerate · regenerate 60hpa	3	2	1.01	1.65
whole 6 week old aboral regenerate · regenerate 48hpa	3	1	0.55	1.65
whole 6 week old aboral regenerate · regenerate 8hpa	3	2	0.43	0.69
whole 6 week old aboral regenerate · regenerate 12hpa	3	1	0.29	0.87

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6320836	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	1.29
SRR6320837	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	0.00
SRR6320863	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	0.00
SRR6320847	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	1.20
SRR6320841	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	0.64
SRR6320838	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	0.59
SRR6320839	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	0.76
SRR6320840	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	0.70
SRR6320846	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	0.35
SRR6320861	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	0.89
SRR6320842	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	0.77
SRR6320848	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	0.00
SRR6320844	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	0.83
SRR6320843	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	0.83
SRR6320845	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	0.35
SRR6320872	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	0.67
SRR6320849	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	0.00
SRR6320873	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	0.00
SRR6320882	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	0.98
SRR6320883	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	0.97
SRR6320850	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	0.00
SRR6320851	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	1.01
SRR6320852	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	0.73
SRR6320855	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	0.00
SRR6320854	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	0.98
SRR6320853	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	0.47
SRR6320856	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	0.00
SRR6320860	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	0.72
SRR6320857	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	0.51
SRR6320859	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	0.00
SRR6320881	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	0.56
SRR6320880	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	0.46
SRR6320858	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	0.40
SRR6320862	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	1.37
SRR6320865	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	1.03
SRR6320864	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	0.00
SRR6320867	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	1.65
SRR6320866	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	1.39
SRR6320869	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	0.00
SRR6320870	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	1.65
SRR6320868	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320871	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320875	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.69
SRR6320874	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.60
SRR6320876	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.00
SRR6320877	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.87
SRR6320878	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00
SRR6320879	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.