Genomic Location: NC_064037.1:7484278...7488342
NR annotation: XP_001639596.2, nuclear inhibitor of protein phosphatase 1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5519617 |
| Transcript |
| rna-XM_001639546.3 |
| Protein |
| XP_001639596.2 |
| UniProt accession | Description |
|---|---|
| Q28147 | Nuclear inhibitor of protein phosphatase 1 OS=Bos taurus OX=9913 GN=PPP1R8 PE=1 SV=1 |
| Q12972 | Nuclear inhibitor of protein phosphatase 1 OS=Homo sapiens OX=9606 GN=PPP1R8 PE=1 SV=2 |
| Q8R3G1 | Nuclear inhibitor of protein phosphatase 1 OS=Mus musculus OX=10090 GN=Ppp1r8 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006210 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00498 all species → | FHA | FHA domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000253 all species → | Domain | Forkhead-associated (FHA) domain | Interproscan |
| IPR008984 all species → | Homologous_superfamily | SMAD/FHA domain superfamily | Interproscan |
| IPR050923 all species → | Family | Cellular Process Regulator and RNA Processing Protein | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23308 all species → | NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0003729 all species → | Molecular Function | mRNA binding | Interproscan |
| GO:0004865 all species → | Molecular Function | protein serine/threonine phosphatase inhibitor activity | Interproscan |
| GO:0016607 all species → | Cellular Component | nuclear speck | Interproscan |
| GO:0035308 all species → | Biological Process | obsolete negative regulation of protein dephosphorylation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K13216 | PPP1R8, NIPP1; nuclear inhibitor of protein phosphatase 1 | EC:3.1.4.- | Spliceosome | ko03041 | deepkoala |
Transcript abundance of XP_001639596.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 2 | 6.21 | 9.54 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 6.03 | 7.82 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 7.02 | 7.46 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 7.35 | 8.18 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 5.92 | 7.05 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 7.98 | 15.81 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 5.52 | 9.02 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 10.62 | 15.64 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 5.62 | 9.45 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 2 | 5.31 | 8.06 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 6.64 | 8.08 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 8.26 | 8.35 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 8.44 | 9.72 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 6.29 | 10.36 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 7.12 | 7.69 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 2 | 8.25 | 16.03 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.