Genomic Location: Sc7jCM8_1359:141088...154524
NR annotation: XP_020602172.1, epidermal growth factor receptor kinase substrate 8-like [Orbicella faveolata]
| CDS | |||||
| LOC110041232 | |||||
| Transcript |
| rna-XM_020746513.1 |
| Protein |
| XP_020602172.1 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| Q5R4H4 | Epidermal growth factor receptor kinase substrate 8 OS=Pongo abelii OX=9601 GN=EPS8 PE=2 SV=2 | ||||
| F1M3L7 | Epidermal growth factor receptor kinase substrate 8 OS=Rattus norvegicus OX=10116 GN=Eps8 PE=1 SV=2 | ||||
| Q12929 | Epidermal growth factor receptor kinase substrate 8 OS=Homo sapiens OX=9606 GN=EPS8 PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Other|SH3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08416 | PTB | Phosphotyrosine-binding domain | Domain | Interproscan |
| PF07653 | SH3_2 | Variant SH3 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| IPR013625 | Domain | Tensin/EPS8 phosphotyrosine-binding domain | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR035462 | Domain | Eps8, SH3 domain | Interproscan |
| IPR039801 | Family | Epidermal growth factor receptor kinase substrate 8-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12287 | EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0003779 | Molecular Function | actin binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0007266 | Biological Process | Rho protein signal transduction | Interproscan |
| GO:0035023 | Biological Process | regulation of Rho protein signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K17277 | EPS8; epidermal growth factor receptor kinase substrate 8 | - | Exosome | ko04147 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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