Detailed information of XP_020610503.1 in Orbicella faveolata

Genomic Location: Sc7jCM8_1014:666333...679857
NR annotation: XP_020610503.1, tRNA (guanine(26)-N(2))-dimethyltransferase-like [Orbicella faveolata]
Species Orbicella faveolata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9NXH9tRNA (guanine(26)-N(2))-dimethyltransferase OS=Homo sapiens OX=9606 GN=TRMT1 PE=1 SV=1
Q3TX08tRNA (guanine(26)-N(2))-dimethyltransferase OS=Mus musculus OX=10090 GN=Trmt1 PE=1 SV=3
Q9VK89tRNA (guanine(26)-N(2))-dimethyltransferase OS=Drosophila melanogaster OX=7227 GN=Trm1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005064 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02005
all species →
TRMN2,N2-dimethylguanosine tRNA methyltransferaseFamilyInterproscan
PF00642
all species →
zf-CCCHZinc finger C-x8-C-x5-C-x3-H type (and similar)FamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036855
all species →
Homologous_superfamilyZinc finger, CCCH-type superfamilyInterproscan
IPR002905
all species →
FamilytRNA methyltransferase, Trm1Interproscan
IPR029063
all species →
Homologous_superfamilyS-adenosyl-L-methionine-dependent methyltransferase superfamilyInterproscan
IPR000571
all species →
DomainZinc finger, CCCH-typeInterproscan
IPR042296
all species →
Homologous_superfamilytRNA methyltransferase, Trm1, C-terminalInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10631
all species →
N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0046872
all species →
Molecular Functionmetal ion bindingInterproscan
GO:0002940
all species →
Biological ProcesstRNA N2-guanine methylationInterproscan
GO:0003723
all species →
Molecular FunctionRNA bindingInterproscan
GO:0004809
all species →
Molecular Functionobsolete tRNA (guanine-N2-)-methyltransferase activityInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0008033
all species →
Biological ProcesstRNA processingInterproscan
GO:0160102
all species →
Molecular FunctiontRNA (guanine(10)-N2)-methyltransferase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00555TRMT1, trm1; tRNA (guanine26-N2/guanine27-N2)-dimethyltransferaseEC:2.1.1.215
EC:2.1.1.216
Transfer RNA biogenesisko03016deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_020610503.1 across 70 RNA-seq samples of Orbicella faveolata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

70Samples
50TPM > 0
4Conditions
466.3Max TPM
74.1Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
holobiont · control.pH_high.temp 21 16 52.63 342.84
holobiont · low.pH_high.temp 19 11 54.97 392.92
holobiont · low.pH Control.temp 16 14 151.45 466.31
holobiont · control.pH Control.temp 14 9 43.91 134.87

Per sample · hover a bar for the full sample record

Show the sample table (70 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR22214540 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 342.84
SRR22214538 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 206.77
SRR22214499 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 96.15
SRR22214536 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 70.81
SRR22214545 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 66.65
SRR22214498 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 66.44
SRR22214501 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 51.53
SRR22214502 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 50.14
SRR22214543 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 34.04
SRR22214539 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 28.81
SRR22214541 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 24.85
SRR22214532 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 22.37
SRR22214542 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 12.41
SRR22214533 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 12.03
SRR22214497 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 9.78
SRR22214534 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 9.63
SRR22214496 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214500 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214531 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214537 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214544 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214472 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 392.92
SRR22214485 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 133.08
SRR22214473 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 102.58
SRR22214478 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 84.28
SRR22214474 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 83.65
SRR22214489 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 77.91
SRR22214482 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 47.07
SRR22214476 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 44.59
SRR22214490 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 36.72
SRR22214479 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 30.79
SRR22214488 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 10.79
SRR22214475 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214477 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214480 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214483 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214484 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214486 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214487 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214491 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214527 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 466.31
SRR22214530 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 350.14
SRR22214519 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 316.45
SRR22214518 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 306.83
SRR22214517 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 256.98
SRR22214523 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 204.18
SRR22214494 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 160.68
SRR22214493 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 105.63
SRR22214520 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 77.98
SRR22214526 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 50.42
SRR22214529 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 39.87
SRR22214521 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 39.56
SRR22214525 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 34.19
SRR22214522 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 14.01
SRR22214495 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214528 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214509 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 134.87
SRR22214507 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 96.45
SRR22214515 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 91.37
SRR22214514 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 60.09
SRR22214513 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 56.04
SRR22214512 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 52.50
SRR22214505 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 46.98
SRR22214504 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 40.12
SRR22214510 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 36.29
SRR22214401 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214503 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214508 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214511 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214516 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00

Source: CnidoSite RNA-seq expression matrices (OFAVE_TPM, StringTie quantification over 70 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Orbicella faveolata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated5XP_020629699.10.801779708165479
Negatively correlated8XP_020623320.1-0.364805149955161

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Orbicella faveolata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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