Detailed information of XP_020620228.1 in Orbicella faveolata

Genomic Location: Sc7jCM8_2850:354474...392387
NR annotation: XP_020620228.1, synaptic functional regulator FMR1-like isoform X1 [Orbicella faveolata]
Species Orbicella faveolata · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q6GLC9Fragile X messenger ribonucleoprotein 1 homolog OS=Xenopus tropicalis OX=8364 GN=fmr1 PE=2 SV=1
P51113Fragile X messenger ribonucleoprotein 1 homolog A OS=Xenopus laevis OX=8355 GN=fmr1-a PE=1 SV=1
Q2KHP9Fragile X messenger ribonucleoprotein 1 homolog B OS=Xenopus laevis OX=8355 GN=fmr1-b PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005946 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF05641
all species →
AgenetAgenet domainDomainInterproscan
PF17904
all species →
KH_9FMRP KH0 domainDomainInterproscan
PF18336
all species →
Tudor_FRX1Fragile X messenger ribonucleoprotein 1, Tudor domainDomainInterproscan
PF00013
all species →
KH_1KH domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR008395
all species →
DomainAgenet-like domainInterproscan
IPR040472
all species →
DomainSynaptic functional regulator FMRP, KH0 domainInterproscan
IPR041560
all species →
DomainFMR1, tudor domainInterproscan
IPR036612
all species →
Homologous_superfamilyK Homology domain, type 1 superfamilyInterproscan
IPR040148
all species →
FamilyFragile X messenger ribonucleoprotein 1Interproscan
IPR004087
all species →
DomainK Homology domainInterproscan
IPR004088
all species →
DomainK Homology domain, type 1Interproscan
IPR016197
all species →
Homologous_superfamilyChromo-like domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10603
all species →
FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003723
all species →
Molecular FunctionRNA bindingInterproscan
GO:0003729
all species →
Molecular FunctionmRNA bindingInterproscan
GO:0003730
all species →
Molecular FunctionmRNA 3'-UTR bindingInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0005844
all species →
Cellular Componentobsolete polysomeInterproscan
GO:0006417
all species →
Biological Processregulation of translationInterproscan
GO:0016020
all species →
Cellular ComponentmembraneInterproscan
GO:0017148
all species →
Biological Processnegative regulation of translationInterproscan
GO:0036464
all species →
Cellular Componentcytoplasmic ribonucleoprotein granuleInterproscan
GO:0042803
all species →
Molecular Functionprotein homodimerization activityInterproscan
GO:0043488
all species →
Biological Processregulation of mRNA stabilityInterproscan
GO:0045182
all species →
Molecular Functiontranslation regulator activityInterproscan
GO:0045727
all species →
Biological Processpositive regulation of translationInterproscan
GO:0003676
all species →
Molecular Functionnucleic acid bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K15516FMR; fragile X mental retardation protein-Messenger RNA biogenesisko03019deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_020620228.1 across 70 RNA-seq samples of Orbicella faveolata. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

70Samples
25TPM > 0
4Conditions
65.9Max TPM
12.9Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
holobiont · control.pH_high.temp 21 8 12.00 57.63
holobiont · low.pH_high.temp 19 4 7.56 62.41
holobiont · low.pH Control.temp 16 6 14.70 65.91
holobiont · control.pH Control.temp 14 7 19.33 64.38

Per sample · hover a bar for the full sample record

Show the sample table (70 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR22214541 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 57.63
SRR22214497 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 56.41
SRR22214501 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 38.77
SRR22214532 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 29.95
SRR22214543 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 27.95
SRR22214542 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 21.38
SRR22214498 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 14.33
SRR22214534 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 5.62
SRR22214496 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214499 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214500 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214502 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214531 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214533 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214536 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214537 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214538 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214539 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214540 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214544 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214545 holobiont · control.pH_high.temp holobiont not recorded control.pH_high.temp SRP406607 0.00
SRR22214490 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 62.41
SRR22214479 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 52.34
SRR22214482 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 18.71
SRR22214488 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 10.11
SRR22214472 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214473 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214474 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214475 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214476 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214477 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214478 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214480 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214483 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214484 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214485 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214486 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214487 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214489 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214491 holobiont · low.pH_high.temp holobiont not recorded low.pH_high.temp SRP406607 0.00
SRR22214529 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 65.91
SRR22214526 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 54.86
SRR22214521 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 46.99
SRR22214522 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 24.18
SRR22214494 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 22.11
SRR22214520 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 21.13
SRR22214493 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214495 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214517 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214518 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214519 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214523 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214525 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214527 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214528 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214530 holobiont · low.pH Control.temp holobiont not recorded low.pH Control.temp SRP406607 0.00
SRR22214507 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 64.38
SRR22214513 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 43.84
SRR22214515 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 41.69
SRR22214510 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 38.34
SRR22214505 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 35.78
SRR22214504 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 27.05
SRR22214514 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 19.47
SRR22214401 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214503 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214508 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214509 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214511 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214512 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00
SRR22214516 holobiont · control.pH Control.temp holobiont not recorded control.pH Control.temp SRP406607 0.00

Source: CnidoSite RNA-seq expression matrices (OFAVE_TPM, StringTie quantification over 70 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Orbicella faveolata tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated4XP_020600487.10.772390702537577
Negatively correlated3XP_020623707.1-0.385853411705455

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Orbicella faveolata, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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