Gene detail

Detailed information of XP_020632199.1 in Orbicella faveolata

Genomic Location: Sc7jCM8_813:27887...62518
NR annotation: XP_020632199.1, C-1-tetrahydrofolate synthase, cytoplasmic-like [Orbicella faveolata]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

rna-XM_020776540.1

ATGGGTGAAATTACTGGGGAAGCAAGGAAGGCACTACAGGGCAGTTGGGTTATTGGAGGTGGAATTGAATTACCATGTATGGAGATTGTTGGAAAAGAAGCCATAGTTCTGGNGGAGGTGGAATTGAATTACCATGTGTGTATTACTTTATGGGAGCAAGAAACACAAAGCGCAAtgaaCATGCACGACTTTGTTCATCTGTTGTCATATCATCGCTACATGTTTATACATGTGAAGTTGTCAAGGACCTCTACTCAAGCAGATGTTCTCAAAGCTGTGGATGAATTGAACAAAGATTCAACGATTCACGGCATCATTGTACAGCTCCCCCCTGATTCTGTGGAGCCAATTGATCCTGCGATTTGCACAAATGCTGTTGCACCAGAGAAGGATGTTGATGGgTTACATGATATAAATGCAGGGAAGCTATCGAGAGGAGAGTTGGATGACTGCATTGTCCCTTGCACTCCCCGAGGATGCCTGGAGTTGATCAAGAAATCAGGTATGGAGATTGTTGGAAAAGAGGCCATAGTTCTGGGAAGAAGCAAAATAGTGGGTTCACCCATGGCAGATCTTCTCAAATGGCATCATGCTACAGTGACAACATGTCACTCAAAGACAAAAGACTTGCCAGATGTGGTGAGAAGGGGTGATATCGTTGTCGTTGGAATTGGAAGAGCTGATTTTGTAAAGGGGGACTGGATTAAGGAGGGTGCAGTGGTCGTCGACTGTGGAATTAATGTGATTCCAGATGAGACTAAAAAGAGTGGGCGTCGTCTCCTTGGTGATGTACATTTTGCAGAAGCAAGGAAAAAAGCAAGCTGGATTACTCCTGTGCCTGGAGGTGTTGGTCCAATGACTGTGGCAATGTTGATGAACAACACAGTGGACAGTGCTAAGAGGGCTCTTCAAATGCAAAAGGGTGGACCTTGGAATATTCGTTACCTTCCTCTCAATCTCCAAAGACCTGTACCAAGCGATATTGACATATCAAAGCAGCAGATGCCAAAGAAAATTGCAGAAGTAGCAAAGGAAGCTACAATTCTTGACTATGAGtgttaCTACCAGGGCACCCCAGTTTTTGTGCATGCAGGGCCCTTTGCTAACATCGCCCATGGAAATTCTTCCATTCTGGCAGATAGGATAGCTTTGAAATTGGTTGGACCAAATGGATTTGTTTTCACTGAAAGTGGTTTTGGAGCTGACATTGGAATGGAGAAGTTCTTTAACATCAAGTGTAGATACAGTGGTTTAACGCCGCATTGTGCTATCATAGTAGGAACTGTCAGAGCATTGAAAATGCATGGTGGAGGACCGAAGgtTGTTGCAGGAAAACCACTCCCACCTGAATATACTTCTgagAACCTAAACCTTGTTAGAAATGGGATGGTGAATCTCGCCAAACAGATTGAGAATGCCCGATTCTTTGGAGTTCACGCAGTTGTTGCTGTCAACAGATTTCCGTATGTCACAATATCAGTCTACCTGTTTTTGCCAATTGAAGATAAGATGAGAATTATTGCCCAGAAGATTTATGGTGCAGATGACATCGAACTGTTACCCGAAGCTGAGAAGAAAGTTGAACGCTATAAAAAGCAGGTTAGTCTAGATGTGTTTGAGTGCAATCATGTAACTTCACTTCAAAGTATTTTCAAGAAAGTTGTATTGCAGGCACGAgaacagctgtcaaaacaaccTGTTGGTTTTACTCTTCCTATCCGTGATGTACGAGCTAGTGTTGGTGCTGGATTCCTCTATCCACTGGTTGGCACTATGAGCACCATGCCAGGACTTCCCACAAGACCTTGCTTCTATGACATTGACTTGGACCCAGTTACAGAAGATGTATTTGGGTTGTTTTAGCCCTCCTAACTCAACTTGTTTTAAGGCTCATAAGAACTCATAGCCAAGAAAACAAGTGTGATTTTTGGTATGTACCCTTACTAGCATGCAGAATTTCCAAGTGATTACACACCATGAATATTACAGAATTGTCCCATAATGTATTGGTTGTTAACATCACTGAACAAGGAATGGAAACTGAAGGCTTGATCAACCAGAAATGGTGCTTGTTAACTTGGCTTATGTGGAATACTGTATGTTCTGAAAGTAGCAAACGTCATTTCTTTCAGGATTAGCAGTCTTTTCCTATTGTTACTTTTGGTGTTGCAAATTTCAGGGGCTTAATTTGTAACTTTTGTGCTGCTTAATCATCTAATGTATGGGGACCCATTTTGCGGTATTGTTGGTGTAAACAGTGATGAAATTATGACTTTAAGTATTTCCACTCATACGTCAAAATGAAATGCTCACTGAACACCAAGTTTAAGTTTATACTGAGTGAAGTTTGAAGGGAGATCAAATTGTGATAAGGTTTTACTGATTTTTCCAAGGCCTCTGCAGGCTTTGAAAATCACTAGTCCACTATCCAGGaagatgttaatttttttgtttggtgggGAAGGGGGAGTGGGTGTGGTTACTCTTGGAATTTTCAGGACTTGTATAACAAGGTGTGTTTTTTGCTGCTGTGAGTGTactatttttgtcatttatctATGAGGAAAcattttaagagaaattaataaTATATCAACTGTAAGAACTGCTTAATGAAGACAGTCGAATGTGCTAAGTACAACTGACATACTTCAAGTTAAAACTGTAGATcattattttagaaaaatgaacttggcattgatgattcttttgtAGGGCTGCAAGTTAATAAGTTATCAAATAATGATAGCAAGGTAAACTTGTCATTATAAACTGGTTTTGGAACAAAATggatgccagaaatggaaagagtgcAATGAAATTGCCAGGGTGCTGATGTCTAAGTGAGATTTAATTGTAGTTTGAAAGTTTCAAACATTGTCAGTGACATGAACCGTGCCACTTGGAAGAAAACTGTAATTGAGCACAATGAAGAGCGATCTTTTTTGTTAACAGACCTGAGtgcagcacagcacagcacaatGCAACACCAGCGTTAATTTTTTCCAGACCAGTCTAGTGCAGCCCAGCACAGCACAAAAGCATGCCAAAGCATTCCTTTCAATGCCAAAGCAATCTTTCGAGGCACTTTTTGCATGGAAGTTTCTCAAATCGCAATAAAAAATTTCCACGTAAATGGCAACAGTTTCATATCGGCAGTCTTACTGTTTTTGCATCTCATTTTAGGCACTCATTTTGTTCTGCAACCGTTGTTTATGATTGACAAAGTCAGATACTGGAGATTGGCAGaaggccaaattttgcataaCAGCCTTAGTGTTTGTGCTAACAGTTAGATTGTAAGGAAATAGGTTTAAGGATGAACAGCTGATGGTCAGCATAAGCCTTATTATCAGGGGCTTAATTGTCATATTTTTCTAGGctcaataaatattttgtttgtaatG

Protein

Uniprot

Uniprot term	Description
P11586	C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4
P27653	C-1-tetrahydrofolate synthase, cytoplasmic OS=Rattus norvegicus OX=10116 GN=Mthfd1 PE=1 SV=3
Q5R8P0	C-1-tetrahydrofolate synthase, cytoplasmic OS=Pongo abelii OX=9601 GN=MTHFD1 PE=2 SV=3

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01268	FTHFS	Formate--tetrahydrofolate ligase	Family	Interproscan
PF02882	THF_DHG_CYH_C	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	Domain	Interproscan
PF00763	THF_DHG_CYH	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR027417	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR020631	Domain	Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain	Interproscan
IPR000559	Family	Formate-tetrahydrofolate ligase, FTHFS	Interproscan
IPR046346	Homologous_superfamily	Aminoacid dehydrogenase-like, N-terminal domain superfamily	Interproscan
IPR020867	Conserved_site	Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site	Interproscan
IPR000672	Family	Tetrahydrofolate dehydrogenase/cyclohydrolase	Interproscan
IPR036291	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR020630	Domain	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR48099	C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004477	Molecular Function	methenyltetrahydrofolate cyclohydrolase activity	Interproscan
GO:0004488	Molecular Function	methylenetetrahydrofolate dehydrogenase (NADP+) activity	Interproscan
GO:0005829	Cellular Component	cytosol	Interproscan
GO:0035999	Biological Process	tetrahydrofolate interconversion	Interproscan
GO:0004329	Molecular Function	formate-tetrahydrofolate ligase activity	Interproscan
GO:0005524	Molecular Function	ATP binding	Interproscan
GO:0003824	Molecular Function	catalytic activity	Interproscan