Gene detail

Detailed information of XP_028394739.1 in Dendronephthya gigantea

Genomic Location: NW_021163022.1:3262604...3275338
NR annotation: XP_028394739.1, EH domain-binding protein 1-like isoform X2 [Dendronephthya gigantea]
Species Dendronephthya gigantea · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_028394739.1

ATGAGTTCCGTTTGGAAACGAATTCAACGCGTTGGCAAACGGGCCTCGAAATTCCAGTTTATCGCTTCGTATCAGACACTAACATTGGAGTGTTCTAGAGATGGGAAATGGCAACCAAATAAACTTAGCGTGATCTGGACGAGACGGAATAGACGAAAAGCTGTCAAGCCAGAAACATGGCAACCAAGTATTGCCAATCCTTTCCGAGGAATGATTGTCTGGACTGATCCTGAGGAAGTGGAGATCAGTGTGACTTTATACAAGGATGCGAGGGAAGGGAGCCCCTTTGAAGATAAGCTTTGGACATTTTTGATTGAAGATGAGTCAGTGACTGGAAAACGTCGTCCAGTAGCAAGTGTTTCTATCAACATGGTGGACTATCATAGCATTGATCTTCAAACATTTTGTCTGAATCTTCCACTGCGACCTGCATCAAAGAAAGTTGTCTCTGCTTCTCTAGATCTGAACCTTGCTTGTGTGCTCCTTAAAGAAGGGAATGCAACAGATGAAGATATGATAAGTATGAGTAGTCTCCTTAGTCTGAATGATCCCTATGGATCTCGTGAGTCTGATTTCGATGCCGGAAAGAACTTTAAAAGAAATGCTGGAAAAAGACTATCTCTAAGATCAGCAAAATCAAAAAGCAAGCCAACATTTAACATGGCAACCAACACAACAAGCTCTAAGGAGGTGAAAAAACATGTAAAAAGCAAAGGAAAGACACACAAGAATGACACAATGAATATGTCATTGCCTGTGGCTAATCATGTTATTGAAAATGGTTTAAATAAACCACTGAGCACAAGTGACACTGATCTTTCAAAAATAGAAAACAGGTCTAGTCCTAAAAAGAAGGAAGATGAAATGTCTGCCCCTGAACAAAGTTTACTGAAGTGGTGTCAGGAATGTGTGAAAGATTATCCTAATGTAGAACTGACTAACATGACGACGTCATGGAGAAATGGCTTGGCATTTTGTGCCATTATACATCATTTCAACTCTGATATGATAGACTTCTCAAGTCTAAAGGAGGACGATGTCAGAGAAAACAACAGACTTGCTTTTGAAGCATTTGAATATCTGGGTATATCCAGAATGTTAGACCCACATCAGATGGTTCTCTCCTCAGTCCCTGATAAACTTCTCATTATGACCTACTTACATCAGATCAAACAGTATTTTACAACAAAAAAGAAAACAATTGAGGAACGTGATGAGGATGATGGCCTCACCTTGGATACCATAGTTGAGGCCGAGCGGAACCTGAGACTGAATACCGAAACTCTAATAAACGATATTGAGAGCAATGATTTTACAAAGTTAAAAGACAGTAAGGAATCTGATACAAAAACAGATCCCCCAAAAGACGTTAAAACGGATATCTCAAACGATAGTAAAACAGACACCTTGACAGACGGTAAGATTGAGTATAAAGCCAATCCTGGGTATAATCCGTTTGATGAAGATGAACCCATCGCTCAGGCGGGTATTAATATCGGATTCACTCCGACAAGTTTGGAAGAAGGAAATATTGAATTTGACGCTGCAGTTGTTGAATCAAAGGAAAAGAACAGGAGTGATGTGGTCTTGAAAGATGAGGAACATAATATATCGTCAGAAAATCATTCACAAACCATTGACAAATGTAATCATGAAAAATTGCGAGAAAATCAGGCGAAAGAAAACGAGCCCAGTGTATGGGAGCACAACCAAAAAACGGGTATCAAAAAACCATCTGTAAAACCGCAAGAAAGAAAAGCGATTACGAGCGAAGACCCGTGGAGGTTGGGGACTAATGATAGTAGAACAAACCAGGCAAAAACAAAAGAGAAAGCCCCAAAACCACCAGAAGAACATGACATAAAAGATTATAAATCAAAACATGAAAATACTGTGCAATATTCTCCTCAACCAGGATTTAATCCATTTGATGAAGAGGTGGATGAAGATTTAAATCAGAATAAACAAGAGTTAAAAACAGAGGATGAGACTTCCATTAAAGGAAAGTCGCTAAATCCGTTTGATGATGATTATATAGATGATGTCGAGGAAAGTAATGTAACTCAGAAGGAAGCACCTAAAAGTTTGAATCCTTTTGATGAGGACTATGACGAACCACTTGAGACTGATTTAGACCAAGTTCTAAGTAAAAATAATGAAGTGAAAACCGGTGAAGAAAGTCACGTGGACAAAGATCCGAGGAGTCGTGACTCGGTAAGGGAAGAGAGAGGTAGTCCTGAGAGAGGAATGGGAACAACTAGCATTAATGAAGTTCTCGTTGCCAATACAAGCCCAAGGCGTAGCCCAATAACTAATTCAAGTAGACTACAAACAGATAATAACCTTGGTGTTACCAAAGACAAATATACCAATAAAACTGATAATACACAGAGAAGTACTTCACCTGTAGTCCACAGTCACACATCATCAGCAAGGACTGTAGATACAAGTCAAACTAATTCTCCTCCTCCTGCGAGATCTACAGAAAATGTACAAGTTACTCAAATGCATCGTAAGGAAATAAGACGGCCCGGAGATCGAACTGGTTCTATGGAGCGACCAACAGCACTGAGCGCAAAGCCGCCTTTTAGGAAACAGTTGACTGAGAGTCATATCAAACCAAAAAGACCAGAATCAGAGAATCTGGGTAGAAAAGGAACACCTACGTCACCAACACCTGGTCGCGGGCAGCTTAGCCTACCAACGTCGCCACGAAGTAGGATTCCATCATTCGAAGAATGGAAAGCAAAGAAATCGGACGATGCTGCAAAACAAGAAGAAATCAAAGCTCAAGCAAGACAAATGATCAAAGAAGCTAGAGCAAGAACGGCAAAATCTCAAACCACTAACCAGGAACCAAGAAACAACGTGGCTTCTAGAATTCCTGTACAAGCTAGCGCCAATCTCCCGCGATTAACATCGTCGAAGAAGTACAAGGCACCAGAACCTCCCGGTGAAAATAGACGCGGGACTTTGGCATCCAAGTTAAAGGATGAGATTGAATATCAGAAGAGAATCACTGAAAAAACTCGAAAAACTTTGGAGTCTTCTCGTATTAAAAGAATCAATCCAAAACAGGAGAATGTGCCCGAAGTTGAGCAGCGAAGCGAGCGAAGTGAGAAAGTACAACAAGCGATAAGGGAGGCCAGGGAGAGACCAAACAGGAAAACTAACCCCCCTGAAACTGAATCGCACCCCCCTGCTGATGATGTGAAGAAAACCGCTAGTATGACAAGCCCACCGAAGCCACCGCGTGTGTATACATATACTGAGGAAGGAGCCAAGTCTGAAGATGAACCTCAAGAGAGTGGGGATGAGCAGCAAATTGATCACCAAACGACTGCAAATAAAAATGAAACGGTAGAGGAACCATTGAACACGCAGGGAGATGAAGAAAATGAGCCAAATCCATCTTTACAACAAAATCCGTTTAAACTGACTTTCAAAAGAAAAGAAACTGTACCGCACGCTGTTGTGAAACCTCTATCTTCAACCACGAGTCGGGAGACAAAGATTGACTTGAAGAAGTACAGCATCAAGTCTCGCAAATTGAGTGAAACTAACAATGAGAGTAACATAAGTACAGCCTTTGGTCAACTGTCCCGTAGTCGCGAGTCATTGTCGTCAGATCATGGCCATTCATCTGAAGAGGACGTTAATGATATATTAGATAATGTTGGTCATGGCTCTGAAAACGAAAATGGATCAGATGAAGAATTGTACGATAATGGTGAAGACGAGGAAGGCTTCCAAGATACATCTCAGTATGTTGAGCACGAGATTGCTGTTTTAGAGGAGGATCGTGTGGCATTAGATCGAGTGGCGGTAAAACTCGAGAAAGAATTGCGGGAAGCCATGAACACAGCAGATTGTAAAGATGAGGAACAGAGATTATTCCAAGAATGGTTTTTGCTTGTGAACAAGAGGAATGAAATTGTCAGACGACAGACGGAATTAAGTATATTAGAAAAGGAAGAAGATTTAGAGAAACGTTTTGAATTGTTAAACAGAGAACTTCGCTTTTTAATGGCTGATAATAAACGAGAAAAAAGTGCACAAGAGAAGAAACGTGAGGAATTGTTGCTGGCGGAGTTAGTTCGTTTGGTAGACAAGCGCGACGAGCTTGTGAGAATAGAAGATTCCCAAGTACAGGAAGCGGAGAAAGCAGCACAACATGTAGATGATGTTGTACGGAACACAAAGATTCCCAAGAAACAGGGTGATTGTTGTATACAATAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8NDI1	EH domain-binding protein 1 OS=Homo sapiens OX=9606 GN=EHBP1 PE=1 SV=3
Q69ZW3	EH domain-binding protein 1 OS=Mus musculus OX=10090 GN=Ehbp1 PE=1 SV=3
Q99MS7	EH domain-binding protein 1-like protein 1 OS=Mus musculus OX=10090 GN=Ehbp1l1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003236 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00307 all species →	CH	Calponin homology (CH) domain	Domain	Interproscan
PF12130 all species →	bMERB_dom	Bivalent Mical/EHBP Rab binding domain	Domain	Interproscan
PF10358 all species →	NT-C2	N-terminal C2 in EEIG1 and EHBP1 proteins	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036872 all species →	Homologous_superfamily	CH domain superfamily	Interproscan
IPR001715 all species →	Domain	Calponin homology domain	Interproscan
IPR050540 all species →	Family	F-actin Monooxygenase Mical	Interproscan
IPR022735 all species →	Domain	bMERB domain	Interproscan
IPR019448 all species →	Domain	NT-type C2 domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23167 all species →	CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005815 all species →	Cellular Component	microtubule organizing center	Interproscan
GO:0030036 all species →	Biological Process	actin cytoskeleton organization	Interproscan
GO:0031941 all species →	Cellular Component	filamentous actin	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K25572	EHBP1; EH domain-binding protein 1	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Co-expression network

Genes whose expression across the transcriptome samples of Dendronephthya gigantea tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

No co-expression network has been built for this species, so this gene has no partners to show. Networks are available for the species listed on the Network Analysis page.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Dendronephthya gigantea, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	no expression matrix	–
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →