Gene detail

Detailed information of XP_029204427.1 in Acropora millepora

Genomic Location: NC_058076.1:11264101...11275430
NR annotation: XP_029204427.1, egl nine homolog 1-like isoform X6 [Acropora millepora]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
P59722	Egl nine homolog 1 (Fragment) OS=Rattus norvegicus OX=10116 GN=Egln1 PE=2 SV=2
Q9GZT9	Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1
Q91YE3	Egl nine homolog 1 OS=Mus musculus OX=10090 GN=Egln1 PE=1 SV=2

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13640	2OG-FeII_Oxy_3	2OG-Fe(II) oxygenase superfamily	Domain	Interproscan
PF01753	zf-MYND	MYND finger	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002893	Domain	Zinc finger, MYND-type	Interproscan
IPR051559	Family	Hypoxia-inducible factor prolyl hydroxylases	Interproscan
IPR044862	Domain	Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain	Interproscan
IPR006620	Domain	Prolyl 4-hydroxylase, alpha subunit	Interproscan
IPR005123	Domain	Oxoglutarate/iron-dependent dioxygenase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12907	EGL NINE HOMOLOG-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0008198	Molecular Function	ferrous iron binding	Interproscan
GO:0031543	Molecular Function	peptidyl-proline dioxygenase activity	Interproscan
GO:0071456	Biological Process	cellular response to hypoxia	Interproscan
GO:0005506	Molecular Function	iron ion binding	Interproscan
GO:0016705	Molecular Function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	Interproscan
GO:0031418	Molecular Function	L-ascorbic acid binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K09592	EGLN, HPH; hypoxia-inducible factor prolyl hydroxylase	EC:1.14.11.29	Renal cell carcinoma	ko05211	deepkoala