Detailed information of XP_031549639.1 in Actinia tenebrosa

Genomic Location: NW_022258378.1:12473...19870
NR annotation: XP_031549639.1, OTU domain-containing protein 5-A-like isoform X1 [Actinia tenebrosa]
Species Actinia tenebrosa · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q08BW0OTU domain-containing protein 5-A OS=Danio rerio OX=7955 GN=otud5a PE=2 SV=1
Q2YDU3OTU domain-containing protein 5 OS=Rattus norvegicus OX=10116 GN=Otud5 PE=1 SV=2
Q3U2S4OTU domain-containing protein 5 OS=Mus musculus OX=10090 GN=Otud5 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005838 (this species only) · gene tree & orthology
Ubiquitin familyDUB|OTU|OTU · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02338
all species →
OTUOTU-like cysteine proteaseFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR003323
all species →
DomainOTU domainInterproscan
IPR038765
all species →
Homologous_superfamilyPapain-like cysteine peptidase superfamilyInterproscan
IPR050704
all species →
FamilyOTU domain-containing ubiquitin thioesteraseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR12419
all species →
OTU DOMAIN CONTAINING PROTEINInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004843
all species →
Molecular Functioncysteine-type deubiquitinase activityInterproscan
GO:0016579
all species →
Biological Processprotein deubiquitinationInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K12655OTUD5, DUBA; OTU domain-containing protein 5EC:3.4.19.12
Ubiquitin systemko04121deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_031549639.1 across 18 RNA-seq samples of Actinia tenebrosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

18Samples
12TPM > 0
6Conditions
65.0Max TPM
12.4Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole organism 5 4 24.19 65.01
Tentacle 4 3 9.11 17.22
Mesentery 3 3 9.81 12.54
Acrorhagi 3 1 5.95 17.86
whole 2 0 0.00 0.00
whole organisim 1 1 18.04 18.04

Per sample · hover a bar for the full sample record

Show the sample table (18 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR2437124 whole organism whole organism not recorded not recorded SRP063756 65.01
SRR4696535 whole organism Whole Organism not recorded not recorded SRP092287 25.32
SRR3210696 whole organism whole organism not recorded not recorded SRP070917 18.81
SRR3206038 whole organism whole organism not recorded not recorded SRP070917 11.84
SRR3193648 whole organism whole organism not recorded not recorded SRP070917 0.00
SRR4677495 Tentacle Tentacle not recorded not recorded SRP092287 17.22
SRR4677522 Tentacle Tentacle not recorded not recorded SRP092287 13.84
SRR6282389 Tentacle Tentacles not recorded not recorded SRP124815 5.40
SRR4677502 Tentacle Tentacle not recorded not recorded SRP092287 0.00
SRR4677518 Mesentery Mesentery not recorded not recorded SRP092287 12.54
SRR4677488 Mesentery Mesentery not recorded not recorded SRP092287 10.78
SRR4677492 Mesentery Mesentery not recorded not recorded SRP092287 6.11
SRR4677512 Acrorhagi Acrorhagi not recorded not recorded SRP092287 17.86
SRR4677507 Acrorhagi Acrorhagi not recorded not recorded SRP092287 0.00
SRR4677515 Acrorhagi Acrorhagi not recorded not recorded SRP092287 0.00
SRR3193284 whole whole not recorded not recorded SRP070917 0.00
SRR3216075 whole whole not recorded not recorded SRP070917 0.00
SRR3207346 whole organisim whole organisim not recorded not recorded SRP070917 18.04

Source: CnidoSite RNA-seq expression matrices (ATENE_TPM, StringTie quantification over 18 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia tenebrosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated9XP_031564730.10.951198188364557
Negatively correlated4XP_031563041.1-0.785605979146269

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia tenebrosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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