Gene detail

Detailed information of XP_031574410.1 in Actinia tenebrosa

Genomic Location: NW_022258171.1:32676...44790
NR annotation: XP_031574410.1, protein-glutamine gamma-glutamyltransferase K-like [Actinia tenebrosa]
Species Actinia tenebrosa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_031574410.1

ATGCCTAGAAGTTCACGAAGGACCAGAGGAAACACTGCTGCTAATTCTACAAGGATTGCCAGCAACTCACCAAGAACTACTAGGAGATCCTCTGGCAGTGGGATGGAACCATCACCGCCAAAGCGAAGGCGAGCCGAATCGCCTGAAAATGATTCCCGAAGAGCAAGGCGAGGAAAACTTGGTGAAAATGTCGAAGGTCGCACCAAAGTCATGACGGATCAGGATTTCAAAGAAAATATGAAAGTTTTGCATGCGAACAGCAAAAAGATGAATGATTCGCAGCTCAAGCCTGTTCAGGTCGACTTGCATGTGGACAAAAACCGCGAGGAACATTACACGGATGACTATGAGATGGAGGATCTCATTGTCCGAAGAGGAAAAGTGTTCAAGATATCCGTGACGTTTGACAGGAATTTTGATGAATCACGAGACAAAGTAATCTTGCAGTTCGTTACAGGCCCTCGACCCCAACAGAGCAAGAAGTCCATCATACGATTGCAGAACAGCAATAGCCTTTCCACGTCATCGTGGGGTATGCACATAGTAGAACATCGTGGAGCAACTGTGGAAATGTCCGTCATGTCACCTGCTGATGCCATTGTTGGAGAGTATTCATTGTTTGTGGAGACACGAAGCAATAGATACGGTGGGAACCATCATAGCTTTAAACAAAAGCGTGATGAGAAAATCATCATATTGTTCAACGCCTGGTGTAAAGATGACGCAGTTTACATGGGCAAAGAAGATGAACGGAAAGAGTACGTACTGAATGATCGCGGGCGCATCTGGGTTGGCAGCAAAAGAAGATTCACAAGCATTCCTTGGAACTTTGGCCAGTTTGATCAAGTTTCACTGGAAACATGCTTAAAGCTATTAAAGATAGCAGAACTCAGTACTTCTGCACATGCAAATCCTACCCTTGTTTGCCGTACTATATCTCAAATGGCTAATTACAACGATAAAGATGGTGGCATACTCTTTGGGCGTTGGACCGAGACCTATCCAAAAAATTCCACCGAGCCCACAGAATGGACCGGAAGTGTCACCATTTTGAAGAAGTTCACAAAGCGATATCAATATGTGCGATATGGACAGTGCTGGGTGTTCTCTGGCTTAGTAACCACACTTCTTCGTGCTATAGGGATCCCAACTCGTAGCGTGACTAACTTTGCGTCGGCACACGACAACGACCAAAGCATGACCATTGATTATCACCATGATGCCGAAGGAAAGCCACTAGATGACCTCGATGATTCAGTATGGAACTTCCATGTGTGGAACGAGTCGTATTTCACTCGTCCAGATCTTCCGTCTGGCTATGATGGCTGGCAGGCACACGATGCCACACCACAGGAAACCAGTGAAGGTGTGTTCAGGTGTGGACCCTGTCCTGTCAAAGCCGTCAAGAATGGCGAGGTTTACTTCCCATTTGACACAGGCTTCGTGTTTGCTGAAGTCAACGGTGATAAAGTCTACTGGGATGTTGATGAGGATGGAGAGATGACAGTGTCTTACATTGATAAACGCAGTATTGGAAAATACATTAGTACCAAGGCCGTTGGAAGCAATGACAGAGAAGATCTGACCAAGTATTACAAGTTTCCGGAGGAAAGCTCACAAGAACGTGAGGCAGTCCGACTAGCTAACAAATTCAGCTCACGCAAAAATCAGGAAATTTATTCCGAGCCATCTTCCAGTGATGTCACGTTTGAAATACTCACCAGTGACAACATAATGATAGGAGATGACGTTAAAATAGAGTTGTCTGTAAAAAATGACTCCAATGCAAGAAGGACTGTTCAGGTTACCATAGTAACCAAGATATCCTTCTACACGGGTATTACCACTCGAGACTTGAAGAATGTTAATAAAGTGGTGACTCTTGCAAGAGGACAGGAAACCTCCGTACTTCTATCTATTTCTGTTGATGAATACCTCAAAATGGCTCCTGATGCAAGCATCAAAACCTACTTCAAAGCTAAAGTCAAGGAGACTGGTCAGGTGTTTTGTGACATGGATGACATTGAATTCAACAAACCTGAACTCATAGCAATGATCCCATATAAGGTGGGGAAAAACGAGGAGTTCGAGGTTTCATTCCAGTTCACCAATCCTCTGCCTATCAAGTTAACAAATGCCAATCTGAACGTTGAAAATTCCAGGATGATCCCAAGCTCTATCACAAAAAGCATAAGGAAAGCGATTGGACCAAATGATGAGGTGTCAATTCCTGTTATTCTGGAATCCAAGAAAAAAGGAAAGCGATACATTGATGCATCTTTCCACTCCGATCAGCTGTCTGGTGTTCGTGGAGAGTTTGAGATTACAGTAGTGTAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P22758	Protein-glutamine gamma-glutamyltransferase K OS=Oryctolagus cuniculus OX=9986 GN=TGM1 PE=2 SV=2
P22735	Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4
P23606	Protein-glutamine gamma-glutamyltransferase K OS=Rattus norvegicus OX=10116 GN=Tgm1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000881 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00868 all species →	Transglut_N	Transglutaminase family	Domain	Interproscan
PF00927 all species →	Transglut_C	Transglutaminase family, C-terminal ig like domain	Domain	Interproscan
PF01841 all species →	Transglut_core	Transglutaminase-like superfamily	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036238 all species →	Homologous_superfamily	Transglutaminase, C-terminal domain superfamily	Interproscan
IPR013783 all species →	Homologous_superfamily	Immunoglobulin-like fold	Interproscan
IPR023608 all species →	Family	Protein-glutamine gamma-glutamyltransferase, animal	Interproscan
IPR001102 all species →	Domain	Transglutaminase, N-terminal	Interproscan
IPR038765 all species →	Homologous_superfamily	Papain-like cysteine peptidase superfamily	Interproscan
IPR008958 all species →	Domain	Transglutaminase, C-terminal	Interproscan
IPR050779 all species →	Family	Protein-glutamine gamma-glutamyltransferases	Interproscan
IPR014756 all species →	Homologous_superfamily	Immunoglobulin E-set	Interproscan
IPR036985 all species →	Homologous_superfamily	Transglutaminase-like superfamily	Interproscan
IPR002931 all species →	Domain	Transglutaminase-like	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR11590 all species →	PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003810 all species →	Molecular Function	protein-glutamine gamma-glutamyltransferase activity	Interproscan
GO:0018149 all species →	Biological Process	peptide cross-linking	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05619	TGM1; transglutaminase 1	EC:2.3.2.13	Enzymes with EC numbers	-	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_031574410.1 across 18 RNA-seq samples of Actinia tenebrosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

18Samples

10TPM > 0

6Conditions

29.9Max TPM

7.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organism	5	4	6.27	11.34
Tentacle	4	4	19.08	29.88
Mesentery	3	1	3.53	10.59
Acrorhagi	3	0	0.00	0.00
whole	2	0	0.00	0.00
whole organisim	1	1	7.81	7.81

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR4696535	whole organism	Whole Organism	not recorded	not recorded	SRP092287	11.34
SRR3193648	whole organism	whole organism	not recorded	not recorded	SRP070917	7.00
SRR3210696	whole organism	whole organism	not recorded	not recorded	SRP070917	6.94
SRR3206038	whole organism	whole organism	not recorded	not recorded	SRP070917	6.04
SRR2437124	whole organism	whole organism	not recorded	not recorded	SRP063756	0.00
SRR4677495	Tentacle	Tentacle	not recorded	not recorded	SRP092287	29.88
SRR4677502	Tentacle	Tentacle	not recorded	not recorded	SRP092287	27.36
SRR4677522	Tentacle	Tentacle	not recorded	not recorded	SRP092287	15.19
SRR6282389	Tentacle	Tentacles	not recorded	not recorded	SRP124815	3.90
SRR4677518	Mesentery	Mesentery	not recorded	not recorded	SRP092287	10.59
SRR4677488	Mesentery	Mesentery	not recorded	not recorded	SRP092287	0.00
SRR4677492	Mesentery	Mesentery	not recorded	not recorded	SRP092287	0.00
SRR4677507	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	0.00
SRR4677512	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	0.00
SRR4677515	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	0.00
SRR3193284	whole	whole	not recorded	not recorded	SRP070917	0.00
SRR3216075	whole	whole	not recorded	not recorded	SRP070917	0.00
SRR3207346	whole organisim	whole organisim	not recorded	not recorded	SRP070917	7.81

Source: CnidoSite RNA-seq expression matrices (ATENE_TPM, StringTie quantification over 18 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.