Gene detail

Detailed information of XP_031574412.1 in Actinia tenebrosa

Genomic Location: NW_022261906.1:51745...76448
NR annotation: XP_031574412.1, chromatin-remodeling ATPase INO80-like [Actinia tenebrosa]
Species Actinia tenebrosa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_031574412.1

ATGGCGTCCCCTATTTCGTCTCCAGCACCACCTTTACATGTCCAACATTTGGAGAAAGCGCTACGACTTGAACCTTTCCTTGGGTTTGTTGAAGGAATTTTTTCCGACCCTTTCCTTTCGAACCTGAGTGACTCAGAAAATAGTGATCTTAGTGATCTGGAAAAAGATTTAGCGTTTAAACCTGAAAATACTGGCTTTGTTAATGGTGATGGGTGTCATGTTACATCAAATGGATTATTGCATAAAGAAGATTTCAATATTGACAAATCAAGGCTGTACAATTTTACGAAAGTAAAGAATGAGCGCRGATGGTTAAAGGATGTCTTGTTGAGTGACAGTTCTGAAAGTTCTGATGAAGATGAACCCATTACTGATGAAGAACTACAGAGGATGCTTTGGTTCCACAAAAAGCAAAAGTCAGCTCAACGAAAATTCTTTCAGGATCAGGATCAGCTGGCATGCTATCAGCATTAYGGCACCAGCCTATTGTCCAGCCAGGATAAGTACCATGACTTCCAGAGACAATTTGCTGGCTCAAWGAAACTCAAGAAAAAGAAGCTGAAGGACAGTAACATGAAGGTGATTAGTGGAAAAAAAGAAAAAGTGAAAATCAAGAAAAAGAAAAAGACTGATGAACAGATAGATGAACAGAAACGACTATCCCTTCAAGAGAAAATTCTCAAGAAAACTCTCATACGAAGAAAAGAAGCTGATGCCAAAAGAAGGAAGATCTGGTCTCACATCTGTAGAAAAGAAATTCCAAGGGCCCAGAGGCAAAAGGCGTCTGCTAGGAATAACATGCTTAGYAATGCAAAGAAGATGTTGGCTTACTGGAAGAAATATGAAAAGGTGGAAAAAGAACACAGAAAAAGAGCTGARAAGGAAGCCATGGAACAGAGGAAGATGGATGATGAACTACGAGAGGCTCGCCGACAGCAAAGAAAGCTGAACTTCCTTATCACCCAAACGGAACTATATGCTCACTTCATGAGCAAGAAACTGAAGAATGCAAAAAATGCAAAATCAGAAGAGGTTCAGAACATCCTGAAAAAGCTTGACGAACCATCCTCAAGTCACATGGTCAAAACAGTACAGGGAGGAGTTGTGTTTGACATTGAAAATGATGATAATTATGATGCGAAGGCCATGAAAATGGAAGCACTAGCGAACGCACAAAATGCATTGAAAGAACAAGAAGCAAGGACCCAAGCATTTGATTCAAGTGTYGAGCAAGAGTATGGTATCAGTAAGAAAATTGCTTTATCACAAGAATCATTTGATGAAAACTTTAGTCTGGCCAACCCTAATCTCACTGCTGACCTTCCTCAACCAAAGCTCTTTCAGGGATTACTAAAAACATATCAGCTGAAGGGAATGAATTGGCTGATTACTTTATATGAGCAGGGTATCAATGGGATTCTTGCTGATGAGATGGGACTAGGCAAGACTGTACAGTCTATAGCATTCTTGTCATATCTGGCTGAGGTCCATCATATCTGGGGTCCATTTCTCGTCGTTGCTCCAGCATCTACACTCCACAACTGGCAACAAGAAGTAGCAAGGTTTATACCTCACTTCAAGGTCCTTCCTTACTGGGGTAATCAAAGTGATAGAAARTCTCTCAGGAAATTCTGGAGCCAGAAACAAACTCACATCAGTGACAGGAATGAAGCACCTTTCCACCTTCTAATTACAAGTTACCAACTGGTTGTGCAAGATGTTCGTTATTTCCAAAGAATAAAGTGGCAGTACATTGTACTTGACGAAGCACAAGCCATCAAGAGTAGTTCAAGTGTTCGATGGAAGATTCTTCTGGGGTATCAATGTAGGAATCGTCTGCTACTGACTGGAACACCCATTCAAAACAGCATGCAAGAGTTGTGGGCTTTACTTCACTTCATTATGCCAACATTGTTTGACTCTCATGAAGAATTCAATGAATGGTTCTCTAAGGACATTGAGAGCCATGCAGAGAACAAGTCCATTATAGACCAAATTATCTCGTCTTCATATGATCTTGAAGCCTTTCATGTTGAGRAGGATCAAGAGAGATGTGGAAAATGAGTTATCAGATAAGATTGAGATCAAGTTAGTTTGCCGACTCACTACCAGACAAAAATGGCTGTACCAGGCTGTTAAGAACAAGATATCCATAGATGATTTGGTCTATACATCAGCTTCATCGTCATCTGCTGCAAATGCAACAACTAGTAGTTTAATGAATCTTGTTATGCAGTTCAGAAAGGTATGTAATCAYCCAGAACTGTTCGAGAGAAGAGATGTCTGTTCCCCTATTTCGTCTTTTCAGCTGGGATGTTTCCTTGTGCCTAAGCTGATCTACAGAGAAGGTCTTGTAGACAGAATGTTTCCAGGCTGTATGAAAATCTTGTATAATACTCTAAATATATGGAYGGCAGAGTATATTACCAAGTCTTTACACTCCTACTCAAAAGGAAATGAACAAGTGCCTGAAAGTTCATGTTTCTCATTCCTTCAGTTCATCAATCTTTCTCCTGAACAAGCATCAGCCATGATGCAGAAAGGATTGACATACAGGATTCTTTTCCTGTGGATTCTGTTACGAGAGGTTCATCATTTGAACCATAAACGAGTCTGGTCWCTTGAAAAGAAGAATTCAAAGCATCAAGACAGACAAGCACTACTTTTTTGGCCAAGCCAACCAATTTCCTTTCCAAACATCCAAACCAGTTCTACTTTGTCTTCTCTAGTCTTCACTGGTTACAYGAAGCAGATCCTCTCACATTTAACACATCGCATTCAACCTATACTAGATGAAAATGACAAAACTCCTAGGACAAGTCACAACCAATCAACTGTGAAATCCCCTCTAAAACACTCAACRACCAGCCCTTTTTCTCCTACTGGCAGTCACCCCATAGCAACTACATCACATCACCACCATCACAAACATCACCACCACCACCACCATCGTCACYGCAAGTCTTCAGAAGGACATGCTATGCCGAGCGAACCAATAGGATTGCCCATGAAGTACCCACAGGAAAGACAACTACAGCCTACTGATGTACCCTCAATTCTGTTAACTTATTTACCAAGGCTTGTTGCAGGCAACAACCTTAGTTACTGTAGTGATCGAAGCGCAGCCTATGAAACGCAAGACCTTCTCCTTGGGGGAACTGAGATGAAGCGTAACCTRCTATTGTACGGAAATCCTGAGGGATGTGATCTTAACCAGGTCAAGATGCAGCTATTCCCATCACCTATTGGTGGGCTGGAAGGCAGTAGGCCGCYTAATGGATGGTCATTTGTCCAGATGCCTAGTCGTAGTGCATTGATAACAGACAGTGGTAAACTAACGGTACTAGATGGACTACTTACAAAGCTGAAGATGCAAGGTCATCGCGTGCTTATTTAYTCCCAGATGACAAGAATGATTGACATCCTTGAGGAATACATGACGTACAGGAAACATAAGTACATGAGACTTGATGGATCGTCCAAGATATCTGATCGAAGAGATATGGTGGCTGACTTCCAGAACAATGCCGACATCTTTGTCTTTCTGTTGAGTACTCGTGCTGGTGGACTGGGTATTAATCTCACAGCAGCTGATACGGTTATCTTCTATGATAGCGACTGGAACCCTACTGTCGATCAACAGGCTATGGATCGTGCACATCGTCTTGGTCAAACCAGACAAGTAACAGTCTACAGACTTGTCACCAAGAACACTATTGAAGAGAGAATATTACAGCGAGCTAAGGAGAAGAGTGAGATTCAAAAGATGGTTATTTCAGGAGGCCATTTCAAACCAGATGCTCTCAAACCCAAAGAAGTGGTGTCCTTGTTACTGGATGATGAAGAACTGGAAAGCAAATTTCTACAGCGACAAGCGGAGAAAAAAGCAGATGAGCAACGAAAGCGAAGAGAAAGGAAAAGGAAGAAAGGGGGACCTGGAGAGATTGACAGCCCATTGTTATCTGAGAATCAAGACACACCACCACCCAAGGCCAAGAAGGGTCGTAAGAGCAAAAGCTCTTTGTTCCCACCAGCACCTGAGACGTTAATAGACAGTGCTAAAACAGCTTCTGAGATCAGCAGCATGAATGGRGACACATCACGTCAAGGAATGACTGATATGGATGAAATAAGTGTCATGAGTCTTGATGAAGTATCACTAGCATCAGGTGACGGATCCATTCTATCAATCGAYGCAGCAYGCAGTGGTGTCCCTACRCCTCTCAGTGGTCGACCAGACAATGACGACTCTATTACATATGAAGATTCCATAAGTGAAACAGCCAGCCCCTTATCTACAGAAAACACTGGCAAGCGTGGTAAAGGACGAGGACGAGGCCGTGGTCGAGGGAGCACAAGCAGAAGAGGCAGAGGTACAGGTCCTTTGAGAGTATCYCGTGGGCGCGGCAGAGGGCGTGGCAGCTCAGGAGCCTTGGCAGCCTCAGCAGCAGCATCTGCAGCAGCAGCAGCAGCCTCAGCTGCAGCTTACGCAGCCTATGGTTTCACATTCCAAGGGACCCCAACACCTACCCCTCCCCCCTCAAGATCCAGTCCTGTGGCTTTTTGTGCTGGAACTTCTTTAGCAGGAAGTAGCACCATTAGTCATCCAGTACCACGCTACGATAATGAAAATGAGAACCCTTGTACTACCACCAATACCAATGAACAATCATCAGGTCTCTCTTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6ZPV2	Chromatin-remodeling ATPase INO80 OS=Mus musculus OX=10090 GN=Ino80 PE=1 SV=2
Q9ULG1	Chromatin-remodeling ATPase INO80 OS=Homo sapiens OX=9606 GN=INO80 PE=1 SV=2
Q9VDY1	Chromatin-remodeling ATPase INO80 OS=Drosophila melanogaster OX=7227 GN=Ino80 PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003801 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF13892 all species →	DBINO	DNA-binding domain	Domain	Interproscan
PF00271 all species →	Helicase_C	Helicase conserved C-terminal domain	Domain	Interproscan
PF00176 all species →	SNF2-rel_dom	SNF2-related domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR050520 all species →	Family	INO80/SWR1 chromatin remodeling helicase	Interproscan
IPR020838 all species →	Domain	DBINO domain	Interproscan
IPR038718 all species →	Homologous_superfamily	SNF2-like, N-terminal domain superfamily	Interproscan
IPR001650 all species →	Domain	Helicase, C-terminal domain-like	Interproscan
IPR049730 all species →	Domain	SNF2/RAD5-like, C-terminal helicase domain	Interproscan
IPR014001 all species →	Domain	Helicase superfamily 1/2, ATP-binding domain	Interproscan
IPR000330 all species →	Domain	SNF2, N-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR45685 all species →	HELICASE SRCAP-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0016887 all species →	Molecular Function	ATP hydrolysis activity	Interproscan
GO:0031011 all species →	Cellular Component	Ino80 complex	Interproscan
GO:0042393 all species →	Molecular Function	histone binding	Interproscan
GO:0043044 all species →	Biological Process	chromatin remodeling	Interproscan
GO:0003677 all species →	Molecular Function	DNA binding	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0140658 all species →	Molecular Function	ATP-dependent chromatin remodeler activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11665	INO80, INOC1; chromatin-remodeling ATPase INO80	EC:5.6.2.-	Chromosome and associated proteins	ko03036	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_031574412.1 across 18 RNA-seq samples of Actinia tenebrosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

18Samples

11TPM > 0

6Conditions

22.9Max TPM

6.5Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organism	5	4	13.36	22.88
Tentacle	4	4	4.66	5.68
Mesentery	3	1	1.78	5.35
Acrorhagi	3	1	1.46	4.38
whole	2	0	0.00	0.00
whole organisim	1	1	21.15	21.15

Per sample · hover a bar for the full sample record

Show the sample table (18 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR2437124	whole organism	whole organism	not recorded	not recorded	SRP063756	22.88
SRR3210696	whole organism	whole organism	not recorded	not recorded	SRP070917	17.47
SRR4696535	whole organism	Whole Organism	not recorded	not recorded	SRP092287	15.96
SRR3206038	whole organism	whole organism	not recorded	not recorded	SRP070917	10.48
SRR3193648	whole organism	whole organism	not recorded	not recorded	SRP070917	0.00
SRR4677495	Tentacle	Tentacle	not recorded	not recorded	SRP092287	5.68
SRR4677502	Tentacle	Tentacle	not recorded	not recorded	SRP092287	5.58
SRR4677522	Tentacle	Tentacle	not recorded	not recorded	SRP092287	4.93
SRR6282389	Tentacle	Tentacles	not recorded	not recorded	SRP124815	2.44
SRR4677492	Mesentery	Mesentery	not recorded	not recorded	SRP092287	5.35
SRR4677488	Mesentery	Mesentery	not recorded	not recorded	SRP092287	0.00
SRR4677518	Mesentery	Mesentery	not recorded	not recorded	SRP092287	0.00
SRR4677512	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	4.38
SRR4677507	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	0.00
SRR4677515	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	0.00
SRR3193284	whole	whole	not recorded	not recorded	SRP070917	0.00
SRR3216075	whole	whole	not recorded	not recorded	SRP070917	0.00
SRR3207346	whole organisim	whole organisim	not recorded	not recorded	SRP070917	21.15

Source: CnidoSite RNA-seq expression matrices (ATENE_TPM, StringTie quantification over 18 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Actinia tenebrosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	38	XP_031564452.1	0.962482045581544
Negatively correlated	8	XP_031569042.1	-0.76896295710352

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Actinia tenebrosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →