Gene detail

Detailed information of XP_031574460.1 in Actinia tenebrosa

Genomic Location: NW_022261912.1:28554...31317
NR annotation: XP_031574460.1, protein-S-isoprenylcysteine O-methyltransferase-like [Actinia tenebrosa]
Species Actinia tenebrosa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9WVM4	Protein-S-isoprenylcysteine O-methyltransferase OS=Rattus norvegicus OX=10116 GN=Icmt PE=2 SV=2
Q9EQK7	Protein-S-isoprenylcysteine O-methyltransferase OS=Mus musculus OX=10090 GN=Icmt PE=2 SV=2
O60725	Protein-S-isoprenylcysteine O-methyltransferase OS=Homo sapiens OX=9606 GN=ICMT PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007311 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF04140 all species →	ICMT	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR025770 all species →	Family	Protein-S-isoprenylcysteine O-methyltransferase	Interproscan
IPR007269 all species →	Family	Isoprenylcysteine carboxyl methyltransferase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12714 all species →	PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004671 all species →	Molecular Function	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	Interproscan
GO:0005783 all species →	Cellular Component	endoplasmic reticulum	Interproscan
GO:0006481 all species →	Biological Process	C-terminal protein methylation	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00587	ICMT, STE14; protein-S-isoprenylcysteine O-methyltransferase	EC:2.1.1.100	Terpenoid backbone biosynthesis	ko00900	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_031574460.1 across 18 RNA-seq samples of Actinia tenebrosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

18Samples

18TPM > 0

6Conditions

17.0Max TPM

8.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organism	5	5	10.69	16.97
Tentacle	4	4	8.05	15.38
Mesentery	3	3	6.85	9.74
Acrorhagi	3	3	8.33	9.72
whole	2	2	2.28	2.43
whole organisim	1	1	9.75	9.75

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR2437124	whole organism	whole organism	not recorded	not recorded	SRP063756	16.97
SRR3210696	whole organism	whole organism	not recorded	not recorded	SRP070917	11.11
SRR4696535	whole organism	Whole Organism	not recorded	not recorded	SRP092287	10.81
SRR3206038	whole organism	whole organism	not recorded	not recorded	SRP070917	10.80
SRR3193648	whole organism	whole organism	not recorded	not recorded	SRP070917	3.74
SRR4677522	Tentacle	Tentacle	not recorded	not recorded	SRP092287	15.38
SRR4677495	Tentacle	Tentacle	not recorded	not recorded	SRP092287	8.34
SRR6282389	Tentacle	Tentacles	not recorded	not recorded	SRP124815	6.62
SRR4677502	Tentacle	Tentacle	not recorded	not recorded	SRP092287	1.84
SRR4677488	Mesentery	Mesentery	not recorded	not recorded	SRP092287	9.74
SRR4677492	Mesentery	Mesentery	not recorded	not recorded	SRP092287	6.28
SRR4677518	Mesentery	Mesentery	not recorded	not recorded	SRP092287	4.52
SRR4677507	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	9.72
SRR4677512	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	8.43
SRR4677515	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	6.84
SRR3216075	whole	whole	not recorded	not recorded	SRP070917	2.43
SRR3193284	whole	whole	not recorded	not recorded	SRP070917	2.14
SRR3207346	whole organisim	whole organisim	not recorded	not recorded	SRP070917	9.75

Source: CnidoSite RNA-seq expression matrices (ATENE_TPM, StringTie quantification over 18 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.