Gene detail

Detailed information of XP_031574481.1 in Actinia tenebrosa

Genomic Location: NW_022261915.1:103662...118016
NR annotation: XP_031574481.1, ral guanine nucleotide dissociation stimulator-like 1 [Actinia tenebrosa]
Species Actinia tenebrosa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

XP_031574481.1

ATGAAGGCTGTCACCAAGACATCTCCGCCAGCTCAGCGCTGTTTCTTTCGTGAAGAAAGAGARGACGGAGCCGTGTATGAAGTTTCTCTCAAGAAAGTTCGCTATCGTCGCAGTGCTAAATATTTAGTGGATATCAGCGAAGAACCGGTCTCTCACTTACAGTGGGAAACAATTCTTGTGCGAAAAATCAAAGCAGGAACTTTGAAGAAACTTGTTGATAATTTAGTATCAGAGAAGGACTCTTTATCCGAAGACTCGGATCCCGGTTATTTAATGGGTTTTTTATCAACTTATCGGGCATTTGCTGAAGTACATGATGTATTGGAACTTCTTATTGAAAGGTGCCTTGATGCTCAGCAAATGAGAATTGAAAGTCCAGAGAAAAGTCTGATTATCATGAAAGGCGTTATTGGAGTKCTTATGGTTTGGCTTGAGCAGTTCTGCTCGGACTTTAATGCGCCGCCAGACTTCGCAGATCTAAAGAGACTGAATAACTTTGTAAATAATCAACTAGAAGGAGATATCAAGAAAGATTTGGCCAAGAAAATTACAGAAAAGCTTCAAACATTTATTATAACACCATATGAAAGTGAAGGGGATCCAATAGGCTTTAGATTGTCTATGCTTAAGGATGTTGATTACATCGTGGAGGCTGACAAAACAAGTGGCTCTTATGAAGGACTTGACTTTGATTTGTTGTCATCCAACCCGGAGTCGTTCGCAGAGCAGCTTACTCTTATGGACGCAGAGTTGTTTCGCAAGGTCATCCCTTGGCACTGTTTAGGCTCAGTATGGTCAAATAGACGACGGAGCAAAGATACTCACAATACAGCAAAACCAACAGTTGAACAATTTAATGCTGTTTCACTGCGAGTGATTTCTACTATCCTTACTTGTTCCAGTAGGAAAAGTACAGCGCCAAGCAAAAGAGCACAATACATAACACGTTGGATCGAGATTGCGCAGGAATGTCGAGATATCAAGAACTTTTCGTCTCTGAGGGCTATTATTTCTGGGCTCCAGTCTGCCTCAATACATAGGCTAAAAAAATCTTGGATGCAAGTCCCAAGGGAAAAACAGCTTTTATTTTCTGAGCTCTCGTCGATTTTTTCAGAGGARAAGAATCAAAAAATGAGCAGAGAGCTTTTGATGAAGGAAGGGACAGCTAAAAGACCAGAATCAGAAACGTCTGGAATAAAAAGACCGAACAGCCTGAAGAAACGACGATCGCGGTTTCTAAACTCAGACTCCGTTATGCAAGGAACAGTACCGTATCTAGGAACATTTTTAACAGATCTGACAATGATTGACACATTATATCCAGATTACACAGAGGATGGATTGATTAATTTTGAGAAAAGACGAAAGGAATTCGAAGTCATTGCACAGATCAAACTTCTGCAAGAAGCCGCAAAAAATTACAACATTGTACCTAATGGAAATTTCAGGCATACGTTTGACTCACTCATGACGTTTTCTGAAGCAGAAAGAAGTCAACCGAGAACTCACCGGTATTAATAAGACATCAGAGAAATCATTCTTCTGGCTCGTCCTCTTCTTCTTCTGGGATCTGTTCAGGTTCAGAAGCAYCAGTCGCCAAGGGGATGTCTATTCCTATAAAGAGAAGGTCTTCTCCGTGTTTCAGATTACCATCTYCACCTGTAACGTCTTCCAATCCTTGGTCTCCTAATAAGTATTCATCCTCTCCGTCACCATTTGCCGGTTTTGGAGGCCTCCAGGCTGGATATATTATCCGTGTAAGCCTTGAAGATGAGGAAGATAGTGGACTTGTATACAAAGGCGTTTGGCTTTCCCAAAGCGAGCGCACACCAACTGTTATTCAAAAATGTTTATTAAAACATGGCYTAAATGAAAACTCTAAAGCGGATTACTGCCTGGTGCAGCAATTACCAAATGGAAATGAACTGGTTTTTCCAGATCACTGCAACGTTTATTATGCGGTCAATTCTAATGCCGAGCCTCTGACATTTCAGCTTCGAAAAAGATAG

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q9NZL6	Ral guanine nucleotide dissociation stimulator-like 1 OS=Homo sapiens OX=9606 GN=RGL1 PE=1 SV=1
Q60695	Ral guanine nucleotide dissociation stimulator-like 1 OS=Mus musculus OX=10090 GN=Rgl1 PE=1 SV=2
Q6P112	Ral guanine nucleotide dissociation stimulator-like 1 OS=Danio rerio OX=7955 GN=rgl1 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004394 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00617 all species →	RasGEF	RasGEF domain	Family	Interproscan
PF00618 all species →	RasGEF_N	RasGEF N-terminal motif	Domain	Interproscan
PF00788 all species →	RA	Ras association (RalGDS/AF-6) domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001895 all species →	Domain	Ras guanine-nucleotide exchange factors catalytic domain	Interproscan
IPR000651 all species →	Domain	Ras-like guanine nucleotide exchange factor, N-terminal	Interproscan
IPR000159 all species →	Domain	Ras-associating domain	Interproscan
IPR019804 all species →	Conserved_site	Ras guanine-nucleotide exchange factor, conserved site	Interproscan
IPR029071 all species →	Homologous_superfamily	Ubiquitin-like domain superfamily	Interproscan
IPR008937 all species →	Family	Ras-like guanine nucleotide exchange factor	Interproscan
IPR036964 all species →	Homologous_superfamily	Ras guanine-nucleotide exchange factor, catalytic domain superfamily	Interproscan
IPR023578 all species →	Homologous_superfamily	Ras guanine nucleotide exchange factor domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23113 all species →	GUANINE NUCLEOTIDE EXCHANGE FACTOR	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005085 all species →	Molecular Function	guanyl-nucleotide exchange factor activity	Interproscan
GO:0007264 all species →	Biological Process	small GTPase-mediated signal transduction	Interproscan
GO:0007165 all species →	Biological Process	signal transduction	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0007265 all species →	Biological Process	Ras protein signal transduction	Interproscan
GO:0043547 all species →	Biological Process	positive regulation of GTPase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K17635	RGL1, RGL; ral guanine nucleotide dissociation stimulator-like 1	-	Ras signaling pathway	ko04014	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_031574481.1 across 18 RNA-seq samples of Actinia tenebrosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

18Samples

10TPM > 0

6Conditions

13.0Max TPM

5.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole organism	5	3	5.82	11.76
Tentacle	4	4	12.14	13.02
Mesentery	3	0	0.00	0.00
Acrorhagi	3	0	0.00	0.00
whole	2	2	5.87	6.23
whole organisim	1	1	7.76	7.76

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR4696535	whole organism	Whole Organism	not recorded	not recorded	SRP092287	11.76
SRR3210696	whole organism	whole organism	not recorded	not recorded	SRP070917	8.72
SRR3206038	whole organism	whole organism	not recorded	not recorded	SRP070917	8.64
SRR2437124	whole organism	whole organism	not recorded	not recorded	SRP063756	0.00
SRR3193648	whole organism	whole organism	not recorded	not recorded	SRP070917	0.00
SRR6282389	Tentacle	Tentacles	not recorded	not recorded	SRP124815	13.02
SRR4677502	Tentacle	Tentacle	not recorded	not recorded	SRP092287	12.68
SRR4677495	Tentacle	Tentacle	not recorded	not recorded	SRP092287	12.03
SRR4677522	Tentacle	Tentacle	not recorded	not recorded	SRP092287	10.81
SRR4677488	Mesentery	Mesentery	not recorded	not recorded	SRP092287	0.00
SRR4677492	Mesentery	Mesentery	not recorded	not recorded	SRP092287	0.00
SRR4677518	Mesentery	Mesentery	not recorded	not recorded	SRP092287	0.00
SRR4677507	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	0.00
SRR4677512	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	0.00
SRR4677515	Acrorhagi	Acrorhagi	not recorded	not recorded	SRP092287	0.00
SRR3216075	whole	whole	not recorded	not recorded	SRP070917	6.23
SRR3193284	whole	whole	not recorded	not recorded	SRP070917	5.50
SRR3207346	whole organisim	whole organisim	not recorded	not recorded	SRP070917	7.76

Source: CnidoSite RNA-seq expression matrices (ATENE_TPM, StringTie quantification over 18 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.