Genomic Location: NC_064035.1:6229494...6245746
NR annotation: XP_032218339.2, adenylate cyclase type 5 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5517880 |
| Transcript |
| rna-XM_032362448.2 |
| Protein |
| XP_032218339.2 |
| UniProt accession | Description |
|---|---|
| Q04400 | Adenylate cyclase type 5 OS=Rattus norvegicus OX=10116 GN=Adcy5 PE=1 SV=2 |
| P84309 | Adenylate cyclase type 5 OS=Mus musculus OX=10090 GN=Adcy5 PE=1 SV=2 |
| P40144 | Adenylate cyclase type 5 OS=Oryctolagus cuniculus OX=9986 GN=ADCY5 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001378 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06327 all species → | Adcy_cons_dom | Adenylate cyclase, conserved domain | Family | Interproscan |
| PF00211 all species → | Guanylate_cyc | Adenylate and Guanylate cyclase catalytic domain | Domain | Interproscan |
| PF16214 all species → | AC_N | Adenylyl cyclase N-terminal extracellular and transmembrane region | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR029787 all species → | Homologous_superfamily | Nucleotide cyclase | Interproscan |
| IPR001054 all species → | Domain | Adenylyl cyclase class-3/4/guanylyl cyclase | Interproscan |
| IPR009398 all species → | Domain | Adenylate cyclase, conserved domain | Interproscan |
| IPR018297 all species → | Conserved_site | Adenylyl cyclase class-4/guanylyl cyclase, conserved site | Interproscan |
| IPR030672 all species → | Family | Adenylate cyclase | Interproscan |
| IPR032628 all species → | Domain | Adenylate cyclase, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45627 all species → | ADENYLATE CYCLASE TYPE 1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0009190 all species → | Biological Process | cyclic nucleotide biosynthetic process | Interproscan |
| GO:0035556 all species → | Biological Process | intracellular signal transduction | Interproscan |
| GO:0004016 all species → | Molecular Function | adenylate cyclase activity | Interproscan |
| GO:0005887 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007189 all species → | Biological Process | adenylate cyclase-activating G protein-coupled receptor signaling pathway | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0006171 all species → | Biological Process | cAMP biosynthetic process | Interproscan |
| GO:0016849 all species → | Molecular Function | phosphorus-oxygen lyase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K08045 | ADCY5; adenylate cyclase 5 | EC:4.6.1.1 | Endocrine resistance | ko01522 | deepkoala |
Transcript abundance of XP_032218339.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 22.36 | 27.20 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 19.38 | 26.99 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 22.23 | 26.80 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 23.14 | 28.75 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 20.51 | 24.56 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 3 | 21.16 | 27.02 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 24.67 | 26.20 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 20.09 | 21.95 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 13.21 | 22.50 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 20.27 | 23.07 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 20.05 | 23.00 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 24.82 | 29.42 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 22.88 | 26.10 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 15.30 | 25.86 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 19.45 | 26.08 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 8.41 | 25.23 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
