Detailed information of XP_032221182.2 in Nematostella vectensis

Genomic Location: NC_064034.1:9771132...9787565
NR annotation: XP_032221182.2, protein patched homolog 1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q13635Protein patched homolog 1 OS=Homo sapiens OX=9606 GN=PTCH1 PE=1 SV=2
Q61115Protein patched homolog 1 OS=Mus musculus OX=10090 GN=Ptch1 PE=1 SV=1
Q90693Protein patched homolog 1 OS=Gallus gallus OX=9031 GN=PTCH1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002045 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02460
all species →
PatchedPatched familyFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR000731
all species →
DomainSterol-sensing domainInterproscan
IPR004766
all species →
FamilyTransmembrane receptor, patchedInterproscan
IPR003392
all species →
FamilyProtein patched/dispatchedInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46022
all species →
PROTEIN PATCHEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0008158
all species →
Molecular Functionhedgehog receptor activityInterproscan
GO:0016020
all species →
Cellular ComponentmembraneInterproscan
GO:0005119
all species →
Molecular Functionsmoothened bindingInterproscan
GO:0005886
all species →
Cellular Componentplasma membraneInterproscan
GO:0045879
all species →
Biological Processnegative regulation of smoothened signaling pathwayInterproscan
GO:0097108
all species →
Molecular Functionhedgehog family protein bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K06225PTCH1; patched 1-Basal cell carcinomako05217deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032221182.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
42TPM > 0
16Conditions
20.2Max TPM
10.9Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 3 12.76 14.63
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 9.17 13.02
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 15.52 20.24
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 14.03 17.07
whole 6 week old aboral regenerate · regenerate uncut 3 3 10.42 12.35
whole 6 week old aboral regenerate · regenerate 4hpa 3 2 8.15 14.27
whole 6 week old aboral regenerate · regenerate 120hpa 3 2 7.41 12.45
whole 6 week old aboral regenerate · regenerate 36hpa 3 3 11.26 12.73
whole 6 week old aboral regenerate · regenerate 24hpa 3 2 7.60 12.82
whole 6 week old aboral regenerate · regenerate 20hpa 3 3 11.74 12.74
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 12.71 14.57
whole 6 week old aboral regenerate · regenerate 72hpa 3 3 14.60 18.81
whole 6 week old aboral regenerate · regenerate 60hpa 3 3 11.38 12.19
whole 6 week old aboral regenerate · regenerate 48hpa 3 2 7.50 14.21
whole 6 week old aboral regenerate · regenerate 8hpa 3 3 14.60 16.18
whole 6 week old aboral regenerate · regenerate 12hpa 3 1 5.03 15.10

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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