Gene detail

Detailed information of XP_032222181.2 in Nematostella vectensis

Genomic Location: NC_064035.1:9995809...10001384
NR annotation: XP_032222181.2, islet cell autoantigen 1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_032366290.2

CTGATCACGGTGCGCGCGCAGCTGACCgccatcttttatttgtgTGAAAAATCAAAGGAATTTGTCTCGTTTCACCTCCATTTATGTTAATATAACCCTCATATATACCCAATGAAACGCCATTCAAAAGGGTAGTGAGCTGTTCAAGTCGTAGAAGATGCAGAGCTCGTACTCACAAGTTCCCCAGGAAGCTGATGAGAACTATGATAGAGGTTTCCAGCGCAACTACCAAGATGATGATGGAATAGATTCTGCAAGCTATGGTTACAACTACAACAACTATCGGCCCCCATCCGGAGGTGTCAAGACCAAAATAGAACACAAGTTTTACCACACCAAACAGGCTGTCATACAGAAGCTAGGCAAGGACCAAGATGCATATGTGGTAGCTGGTGATGCAGAAGTTGATGCTCGTTTGGCGGCTTTCAAGCATATACAGGCCACATGTATTGATTTATTAAAAGCAATTGAGATTTACCAAAACCGGATATTTGCACTCTCTCAAGATGAAAATGAAATGGGGCGCTTTCTTCGTGAACAAGGAGCTGCAGATAAATCTAAAGCAGGGAAGATGATGATTGCAGTGGGCAAAGCACAGAGTTACACTGCTCAACAAAGatTAAGCTTGCGTACACCACTTGTTCGACTATATCAAGAGATTGAAACATTTAGATACAGGGCTATTTCAGACACTGCACTGACTATTGGCCGAATGGAAGGTTCTCGGACAGACTACAGAGCTTCCTTGCTATGGATGTCTGATATATCAAAGGAACTAGACCCTGAAGAATGGAAACGGTTGGACAAATTTAGAGAGGTTCAAAGCCAAGTCAAAAGGACAAAGAAGAAATTTGAGAAGAACAAGTTTGATGTCATGCAAAAAGTAGACCTGCTCTCTGCAAGTCGTTGCAACCTGTTGTCTAGCACCCTGGCGGCGTACCAACAAGCAATGTTGAAATTCTGGGAAAACACCTCCAAGAGTATGAACCAGGTTGCTGAACAGTTCAAGGGCTACCCTAGTTACCAGTTCCAGATGCTTAAAAGTTTAAACCCTCTAGTCACtgacaatgaaaaaaatgatgaaatCAAGGAAGTTCACTTGGACCAAGAAACTCATGTAGACAAGAAGGATACAGAGAATGCAGGAGAAGCAACTGAAGCCAAGaggagtaatgatgatgatgatgatgatgacacacTTATATGCTTGGATAACTCGCCCACAGATGACAAGCCATTACACTTGGGCAATGGCACTGCTGAGAGTAATGGGGACAAGCTAGTTGAGACAGACTTGCTTGGGGATATGACCGTGGAGGGAATAGCTGCTCGCAAGAAAGATGAAGGCCCTAGTCCTTATATTGATTTGTTGGGAGGAGGGGACGATGAAGAAGTTCCCTTTAGGCATGGCTCAGGCAGTAAATCAGCTTCTGATGATCTTCTCGGTGGTTTCGAcgaccacagctcagatcctcCAAGTTATGATATAGCCAAAGACTTGTTGGCCCTTCAGGGACTCGGAAGACCAAATCAAGATGGCAAAGAAGGACAATTGAACCAGCCAGGACCTATGTCTGCGGACGACCTGTTATTCGGATCCCCCACGCGAGAACCAATGAACCAGAACGATCTCGACCTCCTTAGTGACATCATGGGTGGAAGCAACTCTCAGCAACCCTCAGACAGCTTCAGCAGCCAGTGGCAGGACATGTTCGGCGACTCACCAGCTCCTCAGGGTGGGGCAGCCGTGGACCCATCAGGGTTCATGCCATCTGATCTGATGGATAGCTTACTGGGTATGGATTCCATGGGCGGGGCAGCCGCTGGGGCACATTCTTCCTCCTCCACCATGTCATCTGCGCTCTTCGCGGCCAAACCAGCGTCAATGCAGGCTTCCGTCCCACCAGAGAAAAGCGCCGAATGTTTGCCATCCAAAGGGAAGAATAACAAGCCAGGTAAAGGCAAGAAGACGGATATGTCAGCTTGGTTTAACCTGTTCTCGGATCTCGACCCACTCGCTAATCCCGATGCTATTGGGCAGGgtaaaaaacagactgaagaAGAGCGGACTTGCTGAGAGATTATGTCACCAGGGGAAAATCAcccaggactgttatatataGTGAAGTAATACATATTATGAAAATCCTAACCCAACAAGATTAATGAAAATCCTAACCCAACGAGATTAAAGTAAATTATAAGCCGTTGATATGTTACATTTATTCAGGTTCAAAAATGCCaattcaatttttattgtCTTTACTGTCATAACAAATACAAATAAGACGGTTTGAAGCAGTTATTGGGTTTTGTCCCAGGCAAAACTGTATGTTAAATTCGCCAAAAAGCGTAGAGTTAAAGACTCTATCAgagatatattattttttattagtcATAACTATGTCTGATTTAGAAGTGAGAATATAGTTAATGGTCCGGGTTTATAGGTGAAGTGGGTGACATTATTTATTAGATAGGAAACTAAAGTTTCAAGCGAATGGACCAGAGTGTATGCTTGGCACATTTTAGTTGTTAGCGAGGGCTAGAATCTACCGTACTTTTTACCTTTGGTCACAAGCTCCAGCCCATCGCAAAGTGGATTCTATTTCAAAGCTGTTGTGAGCAAACCATAGAAAGAAAGGCGGGGAATAAGAGCCAATGACGCAAGTTTGATTTGGTCACTCGCtatattttgtctttattttattgGGTGCTTTGTACTGTAGAATATGTACGCATAAGGAAGTAAAATTGTCCAATTACATA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q05084	Islet cell autoantigen 1 OS=Homo sapiens OX=9606 GN=ICA1 PE=1 SV=2
Q63054	Islet cell autoantigen 1 OS=Rattus norvegicus OX=10116 GN=Ica1 PE=2 SV=2
P97411	Islet cell autoantigen 1 OS=Mus musculus OX=10090 GN=Ica1 PE=1 SV=3

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005005 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF06456 all species →	Arfaptin	Arfaptin-like domain	Domain	Interproscan
PF04629 all species →	ICA69	Islet cell autoantigen ICA69, C-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR010504 all species →	Domain	Arfaptin homology (AH) domain	Interproscan
IPR024114 all species →	Family	Islet cell autoantigen 1/Ica1-like	Interproscan
IPR006723 all species →	Domain	Islet cell autoantigen Ica1, C-terminal	Interproscan
IPR027267 all species →	Homologous_superfamily	AH/BAR domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10164 all species →	ISLET CELL AUTOANTIGEN 1	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0019904 all species →	Molecular Function	protein domain specific binding	Interproscan
GO:0005794 all species →	Cellular Component	Golgi apparatus	Interproscan
GO:0051049 all species →	Biological Process	regulation of transport	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K19863	ICA1; islet cell auto antigen 1	-	Type I diabetes mellitus	ko04940	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032222181.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

47TPM > 0

16Conditions

60.2Max TPM

38.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole 6 week old aboral regenerate · regenerate 96hpa	3	3	41.36	44.16
whole 6 week old aboral regenerate · regenerate 144hpa	3	3	32.15	39.69
whole 6 week old aboral regenerate · regenerate 0hpa	3	3	37.20	40.75
whole 6 week old aboral regenerate · regenerate 2hpa	3	3	38.12	43.69
whole 6 week old aboral regenerate · regenerate uncut	3	3	31.46	33.05
whole 6 week old aboral regenerate · regenerate 4hpa	3	3	37.07	43.17
whole 6 week old aboral regenerate · regenerate 120hpa	3	3	39.25	40.80
whole 6 week old aboral regenerate · regenerate 36hpa	3	3	39.05	44.81
whole 6 week old aboral regenerate · regenerate 24hpa	3	3	43.64	46.99
whole 6 week old aboral regenerate · regenerate 20hpa	3	3	42.26	43.58
whole 6 week old aboral regenerate · regenerate 16hpa	3	3	40.28	44.65
whole 6 week old aboral regenerate · regenerate 72hpa	3	3	42.48	50.47
whole 6 week old aboral regenerate · regenerate 60hpa	3	3	44.14	50.77
whole 6 week old aboral regenerate · regenerate 48hpa	3	3	47.99	60.25
whole 6 week old aboral regenerate · regenerate 8hpa	3	3	36.24	41.12
whole 6 week old aboral regenerate · regenerate 12hpa	3	2	29.45	45.53

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6320836	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	44.16
SRR6320837	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	41.45
SRR6320863	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	38.47
SRR6320847	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	39.69
SRR6320841	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	28.42
SRR6320838	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	28.34
SRR6320840	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	40.75
SRR6320846	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	38.58
SRR6320839	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	32.26
SRR6320861	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	43.69
SRR6320842	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	37.94
SRR6320848	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	32.74
SRR6320843	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	33.05
SRR6320844	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	31.89
SRR6320845	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	29.44
SRR6320873	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	43.17
SRR6320872	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	39.07
SRR6320849	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	28.96
SRR6320882	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	40.80
SRR6320850	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	39.00
SRR6320883	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	37.94
SRR6320851	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	44.81
SRR6320855	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	36.94
SRR6320852	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	35.40
SRR6320854	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	46.99
SRR6320856	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	42.32
SRR6320853	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	41.60
SRR6320860	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	43.58
SRR6320857	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	41.79
SRR6320859	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	41.40
SRR6320880	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	44.65
SRR6320881	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	39.68
SRR6320858	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	36.50
SRR6320864	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	50.47
SRR6320862	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	40.94
SRR6320865	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	36.02
SRR6320869	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	50.77
SRR6320866	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	40.97
SRR6320867	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	40.68
SRR6320868	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	60.25
SRR6320870	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	45.12
SRR6320871	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	38.61
SRR6320874	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	41.12
SRR6320875	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	37.34
SRR6320876	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	30.24
SRR6320879	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	45.53
SRR6320877	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	42.81
SRR6320878	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.