Genomic Location: NC_064043.1:5671930...5683805
NR annotation: XP_032223148.2, telomerase reverse transcriptase [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC116604624 |
| Transcript |
| rna-XM_032367257.2 |
| Protein |
| XP_032223148.2 |
| UniProt accession | Description |
|---|---|
| O14746 | Telomerase reverse transcriptase OS=Homo sapiens OX=9606 GN=TERT PE=1 SV=1 |
| Q6A548 | Telomerase reverse transcriptase OS=Canis lupus familiaris OX=9615 GN=TERT PE=2 SV=1 |
| Q27ID4 | Telomerase reverse transcriptase OS=Bos taurus OX=9913 GN=TERT PE=3 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005425 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21399 all species → | TERT_C | Telomerase reverse transcriptase, C-terminal extension | Domain | Interproscan |
| PF12009 all species → | Telomerase_RBD | Telomerase ribonucleoprotein complex - RNA binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR049139 all species → | Domain | Telomerase reverse transcriptase, C-terminal extension | Interproscan |
| IPR021891 all species → | Domain | Telomerase ribonucleoprotein complex - RNA-binding domain | Interproscan |
| IPR043502 all species → | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR003545 all species → | Family | Telomerase reverse transcriptase | Interproscan |
| IPR000477 all species → | Domain | Reverse transcriptase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12066 all species → | TELOMERASE REVERSE TRANSCRIPTASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003964 all species → | Molecular Function | RNA-directed DNA polymerase activity | Interproscan |
| GO:0000333 all species → | Cellular Component | telomerase catalytic core complex | Interproscan |
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0003721 all species → | Molecular Function | obsolete telomerase RNA reverse transcriptase activity | Interproscan |
| GO:0007004 all species → | Biological Process | telomere maintenance via telomerase | Interproscan |
| GO:0042162 all species → | Molecular Function | telomeric DNA binding | Interproscan |
| GO:0070034 all species → | Molecular Function | telomerase RNA binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11126 | TERT, EST2; telomerase reverse transcriptase | EC:2.7.7.49 | DNA replication proteins | ko03032 | deepkoala |
Transcript abundance of XP_032223148.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 2 | 1.07 | 1.67 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 0.86 | 1.02 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 1.15 | 1.33 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 0.97 | 1.19 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 0.88 | 1.13 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 1 | 0.40 | 1.19 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 0.91 | 1.48 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 2 | 0.97 | 1.61 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 0.76 | 1.39 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 2 | 0.74 | 1.30 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 0.96 | 1.05 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 2 | 0.89 | 1.60 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 2 | 0.89 | 1.42 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 1 | 0.47 | 1.41 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 0.88 | 1.45 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 0.35 | 1.05 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.