Detailed information of XP_032223148.2 in Nematostella vectensis

Genomic Location: NC_064043.1:5671930...5683805
NR annotation: XP_032223148.2, telomerase reverse transcriptase [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O14746Telomerase reverse transcriptase OS=Homo sapiens OX=9606 GN=TERT PE=1 SV=1
Q6A548Telomerase reverse transcriptase OS=Canis lupus familiaris OX=9615 GN=TERT PE=2 SV=1
Q27ID4Telomerase reverse transcriptase OS=Bos taurus OX=9913 GN=TERT PE=3 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005425 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF21399
all species →
TERT_CTelomerase reverse transcriptase, C-terminal extensionDomainInterproscan
PF12009
all species →
Telomerase_RBDTelomerase ribonucleoprotein complex - RNA binding domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR049139
all species →
DomainTelomerase reverse transcriptase, C-terminal extensionInterproscan
IPR021891
all species →
DomainTelomerase ribonucleoprotein complex - RNA-binding domainInterproscan
IPR043502
all species →
Homologous_superfamilyDNA/RNA polymerase superfamilyInterproscan
IPR003545
all species →
FamilyTelomerase reverse transcriptaseInterproscan
IPR000477
all species →
DomainReverse transcriptase domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR12066
all species →
TELOMERASE REVERSE TRANSCRIPTASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003964
all species →
Molecular FunctionRNA-directed DNA polymerase activityInterproscan
GO:0000333
all species →
Cellular Componenttelomerase catalytic core complexInterproscan
GO:0003677
all species →
Molecular FunctionDNA bindingInterproscan
GO:0003721
all species →
Molecular Functionobsolete telomerase RNA reverse transcriptase activityInterproscan
GO:0007004
all species →
Biological Processtelomere maintenance via telomeraseInterproscan
GO:0042162
all species →
Molecular Functiontelomeric DNA bindingInterproscan
GO:0070034
all species →
Molecular Functiontelomerase RNA bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K11126TERT, EST2; telomerase reverse transcriptaseEC:2.7.7.49
DNA replication proteinsko03032deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032223148.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
34TPM > 0
16Conditions
1.7Max TPM
0.8Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 2 1.07 1.67
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 0.86 1.02
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 1.15 1.33
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 0.97 1.19
whole 6 week old aboral regenerate · regenerate uncut 3 3 0.88 1.13
whole 6 week old aboral regenerate · regenerate 4hpa 3 1 0.40 1.19
whole 6 week old aboral regenerate · regenerate 120hpa 3 2 0.91 1.48
whole 6 week old aboral regenerate · regenerate 36hpa 3 2 0.97 1.61
whole 6 week old aboral regenerate · regenerate 24hpa 3 2 0.76 1.39
whole 6 week old aboral regenerate · regenerate 20hpa 3 2 0.74 1.30
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 0.96 1.05
whole 6 week old aboral regenerate · regenerate 72hpa 3 2 0.89 1.60
whole 6 week old aboral regenerate · regenerate 60hpa 3 2 0.89 1.42
whole 6 week old aboral regenerate · regenerate 48hpa 3 1 0.47 1.41
whole 6 week old aboral regenerate · regenerate 8hpa 3 2 0.88 1.45
whole 6 week old aboral regenerate · regenerate 12hpa 3 1 0.35 1.05

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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