Gene detail

Detailed information of XP_032225445.2 in Nematostella vectensis

Genomic Location: NC_064035.1:7193060...7201992
NR annotation: XP_032225445.2, TGF-beta receptor type-1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_032369554.2

GACCACGTGACCTGTCTGCTTCGCCAGACAGATCTAGACGGCAAAGCGACTTCATTTCATAGCACGAACTGCCTTCGCTCTGTTACCGCCGTTTGTGACCTGTTTTGAcgaattctttatttttttagctagTCAAGTATATACAGAATATCTCAACATGGGTGCAAGGCTTATTTTGTGTCTTGTAGTGTTTTTAGGAGCGGCTTTCGTCACGGATCCTGTATCAAGCATGAAGCTGAACAGACAAATCACTTGCAAATGTGACTACTGCCAGGAAACAAACTCTACCTGTGTCACAAAAGGGGCGTGCCTGACTATCCTACAGAGGGATAGTAGCACGGGTGAGGTCAAGAGGGGTCATGCATGTACATACAATCCCCCAGCGGACCGTCTAGTTTGCGAACCAGGGTATTCAACGGAAAGACCCCACCAGTTATATCACTGCTGTTATTACAATATGTGTAATGTTGATACCAATGTTACATTACCAAGTGTCCCTCCAACAGATCCAGCTGAGGGCAAGACATCTGGTAGAAGTGGAAGGCCTAGTACGGCGGAAGTTGTTGCTATGATCGTTAGCCCTGTTCTAGTAATCTGCCTAGCTACTGTGAGCATAATTTACTGCTACCAAAAGCGCAACCCCCAACGCCAGTGCATTCTCAATGATGGAAGTGAGTCACCTGAAGAAGTCCTTATACCAGCTGGGAAGTCATTATGTGACCTGATAACAAATGCTGATATATCCACAGGTTCTGGATCCGGCTTACCCTTGCTGGTTCAGCGGACAGTAGCCAGACAGATCACTCCAATAGAGCTGATAGGATCAGGTCGCTATGGCGATGTGTACAGGGGCCAGTGGAGAGGAGAGGATGTGGCCGTCAAGATCTTCTCATCCAGGGAGGAGTGCTCATGGTTCAGAGAGGCTCAGATCTATCAGACGGTCATGCTGAGGCATGAAAACATTCTAGGTTTTATTGCAGCTGACAACAAAGACAACGGTGCTTGGACACAGCTATGGCTGATTACCGACTACCATGCCAATGGCTCTCTTTATGACTACCTACAAAGGGTGACACTAGACATGAAATCAATGCTGAAGCTCACCATCTCTATTGCTAGTGGGCTGGCACATCTGCACATGGAGATTATTGGTACTCAGGGCAAGCCTGCCATTGCCCACAGGGATCTAAAGAGTAGAAACATCTTGGTAAAGGACAATGGTACTTGTTGTATTGCTGACCTTGGTCTCGCAGTGTGCCATAACTCTGAGCAGGACACTCTTGATATTCCTTATGGCAACCGTGTTGGCACCAGACGCTATATGGCACCAGAGTTCCTGGAAGACAGTAACCAAGTGCGTAACTTCTGTGCATACAAACATGGTGATATCTACGCATTTGGTCTGGTACTCTGGGAGATAACTCGAAGATGTATATGCAGTGACAAGTGTGAGGATTACCAGTTGCCTTACTTTGACAAGATCTGTGTCGACCCAAGCATTGAGGAAGTATGGAAAGTGGTCTGTTTGGAGAAGTACAGGCCTTCCCATCCCAACTACTGGTTGCAGGATCAGGTGATGATGAGAGTTGCTAAACTCATGCAGGAGTGTTGGCATCACAGTCCTGAAGCAAGACTTCCAGCCCTGCGCATTAAGAAAACTCTGCAGTCACTCTATACAGAAGAGTGCTCAGATCACTGTGTCAAAGCATAACCGAGAAAAGGCTATCAGCTGTATGGGTCATGGTGGAGCCTCGAAGGGCTGTGTGAATGTCATCCCCTGAAACCTAGGGGCAATGGAGCTGCAACAAATCATAACGGAGAAAAAGCTATCCGCTGTTTGGGTCATGGTGGAGCCTCGAAGTGCTGTGCGAAATTCCTCCCCTAAAACCTAGGGGCAAAGGAACTGCAACAAATCATAACTGAGAAAAGGCTATAAGCTGTTTGGGTCATTGTGGAGCCTCGAAAAACTGGGTGAAAGTCATCCCCTGAAACCTAGGGGCAAAGGAACTGCAACAAATCATAACTGAGTAAAGGCTATTAGCTGTATGCGTCATGGTAGAACATTGAAGTGATGTGTGAAAGTCATCCCCTGAAACCTAGGGGCAATGGAGCTGCAACAAATCATAACTGAGAAAAGATTGGCACCAACAAAGGAGGTCATCAGTGCCAATCAAAGTAAatactaccccctcccccttcccggCAAGAGCTTGCCCCGGGGGCAGAGATCTTCTTGTGTCACCCTTTCACTTTGCTCCACTGATATGGGGTAAAGTATACAAGTGACACAGAAAGCTTTGTTAAGGAGAGTAGGTAAATACATTCCAAAAACGAAGTAGCATTAATAGGGGTAAGAACAAGATTACCAATACcccttttaaaagaaaatgtaaaaaaaaacttctgaTCATTATGTGATTTCTTTGTGAAACCCTAGTATTTACCAAGAAATCATATAATGATTACTTGCATATCGTCTGTGTTaacttcaaaattaaaaaatagagaaaagaTGGAAGGAGGATTACAGTCTTCTAAAGGCGATTTTTATCACTTATACATAGCTTGATGATATTGTAAAGAACCAGAAACATGCCATCAGAAACTTAAGGTGAATGCacattatttttatctgtaccaatccaccttttttcacattttatgTAGTGCTTGATCTTTTTTTAGGCTTCCATTCCCCTCAAATTTCTAATGGtttgttgttttctgtttaTCAGTTTTAGAGTTTTCTGTTTTGATCAGTTTTTTGTAGAATGCAAAGTGGgctaccatggcaaccaaagacAACAGTGTTTGGAGTGTCAGCCTTCTGACTTCCTGTGGTACAAAGTTCACAGTTGTCAATGACAAACTTTTTAATAGATATGTCCTGATGCGATCACAAGAATTTCTCACCCATGCTGTCATCGGAAAGCATGTTTTTCACACTCTGTTTAGCAGTATTTTGATTAACAAGGTGACCCACCTTGCGTTGTCAAAGATCTTAAGAAATAATTTATCTTTATATAAAGACATAGAAAATTGTATATCAAAcaaattaaaatgtttttgttaaa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q5CD18	TGF-beta receptor type-1 OS=Sus scrofa OX=9823 GN=TGFBR1 PE=2 SV=1
O46680	TGF-beta receptor type-1 OS=Bos taurus OX=9913 GN=TGFBR1 PE=2 SV=1
P80204	TGF-beta receptor type-1 OS=Rattus norvegicus OX=10116 GN=Tgfbr1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000510 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08515 all species →	TGF_beta_GS	Transforming growth factor beta type I GS-motif	Family	Interproscan
PF07714 all species →	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR000333 all species →	Family	Ser/Thr protein kinase, TGFB receptor	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR003605 all species →	Domain	GS domain	Interproscan
IPR045860 all species →	Homologous_superfamily	Snake toxin-like superfamily	Interproscan
IPR001245 all species →	Domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23255 all species →	TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0004675 all species →	Molecular Function	transmembrane receptor protein serine/threonine kinase activity	Interproscan
GO:0005886 all species →	Cellular Component	plasma membrane	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0007178 all species →	Biological Process	cell surface receptor protein serine/threonine kinase signaling pathway	Interproscan
GO:0007399 all species →	Biological Process	nervous system development	Interproscan
GO:0016020 all species →	Cellular Component	membrane	Interproscan
GO:0016361 all species →	Molecular Function	activin receptor activity, type I	Interproscan
GO:0032924 all species →	Biological Process	activin receptor signaling pathway	Interproscan
GO:0043235 all species →	Cellular Component	receptor complex	Interproscan
GO:0048179 all species →	Cellular Component	activin receptor complex	Interproscan
GO:0048185 all species →	Molecular Function	activin binding	Interproscan
GO:0071363 all species →	Biological Process	cellular response to growth factor stimulus	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

No KEGG orthology assignment for XP_032225445.2.

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032225445.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

40TPM > 0

16Conditions

24.0Max TPM

6.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole 6 week old aboral regenerate · regenerate 96hpa	3	3	5.74	6.98
whole 6 week old aboral regenerate · regenerate 144hpa	3	3	4.24	6.05
whole 6 week old aboral regenerate · regenerate 0hpa	3	3	8.71	10.45
whole 6 week old aboral regenerate · regenerate 2hpa	3	3	10.20	11.40
whole 6 week old aboral regenerate · regenerate uncut	3	3	6.64	7.71
whole 6 week old aboral regenerate · regenerate 4hpa	3	3	13.70	23.95
whole 6 week old aboral regenerate · regenerate 120hpa	3	2	3.69	5.82
whole 6 week old aboral regenerate · regenerate 36hpa	3	3	6.90	7.65
whole 6 week old aboral regenerate · regenerate 24hpa	3	2	5.27	8.95
whole 6 week old aboral regenerate · regenerate 20hpa	3	3	9.01	10.04
whole 6 week old aboral regenerate · regenerate 16hpa	3	3	8.39	9.70
whole 6 week old aboral regenerate · regenerate 72hpa	3	3	5.26	5.65
whole 6 week old aboral regenerate · regenerate 60hpa	3	2	3.53	5.91
whole 6 week old aboral regenerate · regenerate 48hpa	3	1	2.49	7.47
whole 6 week old aboral regenerate · regenerate 8hpa	3	2	5.10	7.65
whole 6 week old aboral regenerate · regenerate 12hpa	3	1	3.41	10.23

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6320863	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	6.98
SRR6320836	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	5.54
SRR6320837	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	4.71
SRR6320847	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	6.05
SRR6320838	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	3.90
SRR6320841	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	2.78
SRR6320846	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	10.45
SRR6320839	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	7.86
SRR6320840	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	7.81
SRR6320861	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	11.40
SRR6320842	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	10.17
SRR6320848	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	9.04
SRR6320843	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	7.71
SRR6320844	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	7.17
SRR6320845	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	5.04
SRR6320873	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	23.95
SRR6320872	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	9.31
SRR6320849	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	7.85
SRR6320882	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	5.82
SRR6320883	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	5.25
SRR6320850	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	0.00
SRR6320855	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	7.65
SRR6320851	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	6.92
SRR6320852	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	6.15
SRR6320854	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	8.95
SRR6320853	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	6.88
SRR6320856	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	0.00
SRR6320857	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	10.04
SRR6320859	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	8.91
SRR6320860	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	8.08
SRR6320880	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	9.70
SRR6320881	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	8.37
SRR6320858	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	7.08
SRR6320862	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	5.65
SRR6320864	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	5.10
SRR6320865	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	5.02
SRR6320866	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	5.91
SRR6320867	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	4.69
SRR6320869	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	0.00
SRR6320870	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	7.47
SRR6320868	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320871	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320875	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	7.65
SRR6320874	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	7.63
SRR6320876	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.00
SRR6320877	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	10.23
SRR6320878	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00
SRR6320879	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.