Detailed information of XP_032229995.2 in Nematostella vectensis

Genomic Location: NC_064044.1:2636284...2694615
NR annotation: XP_032229995.2, E3 ubiquitin-protein ligase UBR5-like isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q80TP3E3 ubiquitin-protein ligase UBR5 OS=Mus musculus OX=10090 GN=Ubr5 PE=1 SV=2
O95071E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2
Q62671E3 ubiquitin-protein ligase UBR5 OS=Rattus norvegicus OX=10116 GN=Ubr5 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002381 (this species only)
Ubiquitin familyE3|E3 activity|HECT · all ubiquitin genes in this species
Ubiquitin familyE3|E3 activity|UBR-box · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00658
all species →
PABPPoly-adenylate binding protein, unique domainFamilyInterproscan
PF00632
all species →
HECTHECT-domain (ubiquitin-transferase)DomainInterproscan
PF11547
all species →
E3_UbLigase_EDDE3 ubiquitin ligase EDDDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR003126
all species →
DomainZinc finger, UBR-typeInterproscan
IPR000569
all species →
DomainHECT domainInterproscan
IPR002004
all species →
DomainPolyadenylate-binding protein/Hyperplastic disc proteinInterproscan
IPR009091
all species →
Homologous_superfamilyRegulator of chromosome condensation 1/beta-lactamase-inhibitor protein IIInterproscan
IPR024725
all species →
DomainE3 ubiquitin-protein ligase UBR5, ubiquitin-associated domainInterproscan
IPR035983
all species →
Homologous_superfamilyHECT, E3 ligase catalytic domainInterproscan
IPR015940
all species →
DomainUbiquitin-associated domainInterproscan
IPR047503
all species →
DomainE3 ubiquitin-protein ligase UBR5, UBR-boxInterproscan
IPR036053
all species →
Homologous_superfamilyPABC (PABP) domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46276
all species →
E3 UBIQUITIN-PROTEIN LIGASE UBR5Interproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0008270
all species →
Molecular Functionzinc ion bindingInterproscan
GO:0004842
all species →
Molecular Functionubiquitin-protein transferase activityInterproscan
GO:0003723
all species →
Molecular FunctionRNA bindingInterproscan
GO:0043130
all species →
Molecular Functionubiquitin bindingInterproscan
GO:0000209
all species →
Biological Processprotein polyubiquitinationInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0005737
all species →
Cellular ComponentcytoplasmInterproscan
GO:0034450
all species →
Molecular Functionubiquitin-ubiquitin ligase activityInterproscan
GO:0090263
all species →
Biological Processpositive regulation of canonical Wnt signaling pathwayInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K10593EDD1, UBR5; E3 ubiquitin-protein ligase EDD1EC:2.3.2.26
Ubiquitin systemko04121deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032229995.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
45TPM > 0
16Conditions
17.2Max TPM
8.1Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 3 9.86 12.69
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 5.62 7.50
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 5.97 6.99
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 6.61 9.05
whole 6 week old aboral regenerate · regenerate uncut 3 3 4.30 5.58
whole 6 week old aboral regenerate · regenerate 4hpa 3 2 7.54 13.02
whole 6 week old aboral regenerate · regenerate 120hpa 3 2 5.42 8.76
whole 6 week old aboral regenerate · regenerate 36hpa 3 3 10.46 11.29
whole 6 week old aboral regenerate · regenerate 24hpa 3 3 9.76 11.65
whole 6 week old aboral regenerate · regenerate 20hpa 3 3 10.62 11.31
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 7.39 8.58
whole 6 week old aboral regenerate · regenerate 72hpa 3 3 11.68 16.20
whole 6 week old aboral regenerate · regenerate 60hpa 3 3 9.08 9.86
whole 6 week old aboral regenerate · regenerate 48hpa 3 3 13.37 17.23
whole 6 week old aboral regenerate · regenerate 8hpa 3 3 7.42 8.75
whole 6 week old aboral regenerate · regenerate 12hpa 3 2 5.19 8.63

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

TOP