Detailed information of XP_032234831.2 in Nematostella vectensis

Genomic Location: NC_064047.1:9135446...9149821
NR annotation: XP_032234831.2, trifunctional purine biosynthetic protein adenosine-3 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P21872Trifunctional purine biosynthetic protein adenosine-3 OS=Gallus gallus OX=9031 GN=GART PE=1 SV=1
Q64737Trifunctional purine biosynthetic protein adenosine-3 OS=Mus musculus OX=10090 GN=Gart PE=1 SV=3
P22102Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002861 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00551
all species →
Formyl_trans_NFormyl transferaseDomainInterproscan
PF02843
all species →
GARS_CPhosphoribosylglycinamide synthetase, C domainDomainInterproscan
PF00586
all species →
AIRSAIR synthase related protein, N-terminal domainDomainInterproscan
PF02769
all species →
AIRS_CAIR synthase related protein, C-terminal domainDomainInterproscan
PF01071
all species →
GARS_APhosphoribosylglycinamide synthetase, ATP-grasp (A) domainDomainInterproscan
PF02844
all species →
GARS_NPhosphoribosylglycinamide synthetase, N domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR011054
all species →
Homologous_superfamilyRudiment single hybrid motifInterproscan
IPR001555
all species →
Active_sitePhosphoribosylglycinamide formyltransferase, active siteInterproscan
IPR011761
all species →
DomainATP-grasp foldInterproscan
IPR004733
all species →
FamilyPhosphoribosylformylglycinamidine cyclo-ligaseInterproscan
IPR036921
all species →
Homologous_superfamilyPurM-like, N-terminal domain superfamilyInterproscan
IPR037123
all species →
Homologous_superfamilyPhosphoribosylglycinamide synthetase, C-domain superfamilyInterproscan
IPR020560
all species →
DomainPhosphoribosylglycinamide synthetase, C-domainInterproscan
IPR004607
all species →
FamilyPhosphoribosylglycinamide formyltransferaseInterproscan
IPR000115
all species →
FamilyPhosphoribosylglycinamide synthetaseInterproscan
IPR036477
all species →
Homologous_superfamilyFormyl transferase, N-terminal domain superfamilyInterproscan
IPR036676
all species →
Homologous_superfamilyPurM-like, C-terminal domain superfamilyInterproscan
IPR013815
all species →
Homologous_superfamilyATP-grasp fold, subdomain 1Interproscan
IPR002376
all species →
DomainFormyl transferase, N-terminalInterproscan
IPR016185
all species →
Homologous_superfamilyPre-ATP-grasp domain superfamilyInterproscan
IPR016188
all species →
DomainPurM-like, N-terminal domainInterproscan
IPR010918
all species →
DomainPurM-like, C-terminal domainInterproscan
IPR020561
all species →
DomainPhosphoribosylglycinamide synthetase, ATP-grasp (A) domainInterproscan
IPR020559
all species →
Conserved_sitePhosphoribosylglycinamide synthetase, conserved siteInterproscan
IPR020562
all species →
DomainPhosphoribosylglycinamide synthetase, N-terminalInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR10520
all species →
TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATEDInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan
GO:0046872
all species →
Molecular Functionmetal ion bindingInterproscan
GO:0004641
all species →
Molecular Functionphosphoribosylformylglycinamidine cyclo-ligase activityInterproscan
GO:0006189
all species →
Biological Process'de novo' IMP biosynthetic processInterproscan
GO:0004637
all species →
Molecular Functionphosphoribosylamine-glycine ligase activityInterproscan
GO:0009113
all species →
Biological Processpurine nucleobase biosynthetic processInterproscan
GO:0005829
all species →
Cellular ComponentcytosolInterproscan
GO:0006164
all species →
Biological Processpurine nucleotide biosynthetic processInterproscan
GO:0046084
all species →
Biological Processadenine biosynthetic processInterproscan
GO:0004644
all species →
Molecular Functionphosphoribosylglycinamide formyltransferase activityInterproscan
GO:0009058
all species →
Biological Processbiosynthetic processInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K11787GART; phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligaseEC:6.3.4.13
EC:2.1.2.2
EC:6.3.3.1
Antifolate resistanceko01523deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032234831.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
39TPM > 0
16Conditions
10.1Max TPM
4.1Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 3 5.18 6.04
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 3.40 4.16
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 1.53 1.73
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 3.53 4.30
whole 6 week old aboral regenerate · regenerate uncut 3 3 2.16 2.59
whole 6 week old aboral regenerate · regenerate 4hpa 3 1 1.64 4.91
whole 6 week old aboral regenerate · regenerate 120hpa 3 2 2.82 4.59
whole 6 week old aboral regenerate · regenerate 36hpa 3 3 8.79 9.82
whole 6 week old aboral regenerate · regenerate 24hpa 3 3 6.92 8.12
whole 6 week old aboral regenerate · regenerate 20hpa 3 2 3.84 6.17
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 3.50 4.07
whole 6 week old aboral regenerate · regenerate 72hpa 3 2 4.33 6.65
whole 6 week old aboral regenerate · regenerate 60hpa 3 3 7.56 10.05
whole 6 week old aboral regenerate · regenerate 48hpa 3 2 6.31 9.92
whole 6 week old aboral regenerate · regenerate 8hpa 3 2 2.75 4.31
whole 6 week old aboral regenerate · regenerate 12hpa 3 1 1.15 3.46

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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