Genomic Location: NC_064042.1:2240120...2259044
NR annotation: XP_032234889.2, structural maintenance of chromosomes protein 6 isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5509932 |
| Transcript |
| rna-XM_032378998.2 |
| Protein |
| XP_032234889.2 |
| UniProt accession | Description |
|---|---|
| Q6P9I7 | Structural maintenance of chromosomes protein 6 OS=Xenopus laevis OX=8355 GN=smc6 PE=2 SV=1 |
| Q924W5 | Structural maintenance of chromosomes protein 6 OS=Mus musculus OX=10090 GN=Smc6 PE=1 SV=1 |
| Q96SB8 | Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001808 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13476 all species → | AAA_23 | AAA domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR038729 all species → | Domain | Rad50/SbcC-type AAA domain | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR19306 all species → | STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0006302 all species → | Biological Process | double-strand break repair | Interproscan |
| GO:0016887 all species → | Molecular Function | ATP hydrolysis activity | Interproscan |
| GO:0000724 all species → | Biological Process | double-strand break repair via homologous recombination | Interproscan |
| GO:0003684 all species → | Molecular Function | damaged DNA binding | Interproscan |
| GO:0003697 all species → | Molecular Function | single-stranded DNA binding | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0030915 all species → | Cellular Component | Smc5-Smc6 complex | Interproscan |
| GO:0035861 all species → | Cellular Component | site of double-strand break | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K22804 | SMC6; structural maintenance of chromosomes protein 6 | - | DNA repair and recombination proteins | ko03400 | deepkoala |
Transcript abundance of XP_032234889.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 17.67 | 18.27 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 12.40 | 17.97 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 11.31 | 11.92 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 10.78 | 11.90 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 10.65 | 12.25 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 6.84 | 11.65 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 16.54 | 18.55 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 15.96 | 18.26 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 7.24 | 12.25 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 10.64 | 10.96 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 10.91 | 11.77 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 15.03 | 19.40 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 20.41 | 27.01 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 11.37 | 19.89 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 9.26 | 13.90 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 3.78 | 11.35 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.