Gene detail

Detailed information of XP_032235183.2 in Nematostella vectensis

Genomic Location: NC_064044.1:10200632...10211102
NR annotation: XP_032235183.2, kynureninase isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_032379292.2

ATATTCTGAATCTTTGCCTTCCTTTGACATTTTGAACCGACTTACCTCACCGCTGACTAACTTTACTACGAACAGGATCGATTAACTTGTACAAACGTCACCATCAATTTAGTCTTTTGAATTTGCACGAAAATGAGTAATCTAGCTAGTAGGATGGCTTATAAACCTACCCAAACTCTTCGTAAACTCGCAGAAAAATCGTCCCTGGACATTGTCTCCCGTGAGTTTGCAGACTATATGGATAGCAAAGATCCTTTGAGAAAAATGCGAGATGAGTTCTTCTATCCTCGTGTGAAAGATTTGCCTGGAGGTGAGGGTCATTATTCTGAATTGAGATTTGTTGATCTGTCACTAGTTGATGGTGACCAGGATTCAATATATTTTTGCGGCAATTCCTTGGGACTTCAACCTCGTGGATGTAGAGAACTTATTGATAGAAGTCTAACAAAGTGGGAACAAATGGGTGTACTTGGGCATACGTCGGGATGGTGTCCATGGAAACCAATTGAGGATATTCTTATCAAACCTATGGCAGAGATAATAGGTGCGAAAGATATTGAAGTTGTAGCTATGAACACACTGACGGTTAATCTGCATATGATGATGGTACCGTTTTACCGTCCGACACCCCAACGGTATAAGATTTTAATGGAGGGAAAAGCTTTTCCCTCAGATCAGTATGCCGCTCAGTCTCAAGTTCACTTTCATGGCTTTGACCCAGACAAAGACATCATAGAAGTTTTCCCACGAGAGGGAGAGCAGAGTTTAAGAACAGAAGATATTTTATCAGCAATTGAGGAGCATGGGAATTCAATAGCACTTGTTCTTTTTTCAGGGGTCCAATATTACACTGGACAGTTCTTTGATATGAAAACAATCACTGCTGCGGCACAGAAAAAGGGCTGCGTAGTTGGCTGGGACCTCGCACATGCTGTTGGCAATGTAGAGCTTCATCTGCATGACTGGAATGTGGACTTTGCCTGTTGGTGCACCTACAAGtaCCTAAATTCAGGGCCGGGTGGTATTGCTGGCGCATTTGTCCACGAGAAACATGCATATAACTTCGAACTTCCAAAGTTTGCTGGTTGGTGGGGGACAGACAGAAATAGCAGATTTCAGATGAGAAAAGAATTTGAGCAAATTCCTGGCGCTCACGGCTACCAGTGCTCCAACCCTCCCGTGTTCCAGTGTCTTTTACTTAGAGCCAGTCTAGATGTTTTCGAGAAGACTTCTGTTAAAGAAATTCGTGCTAAAGGAGACCTTTTGACAGctTATTTAGAGCTTCTACTTCTACACTATTTCTCACCATCTAACGACATCACTAAAAACGGCAAAACCCCACATGTCTCTATAATAACACCCACGGACCCGAAAGACCGCGGATGCCAGCTGTCAGTGAAATTCTCAGTCCCTGTTGATAAGGTGTTTGAAGAGCTGTGTAAACGAGGCTTTGTGGGAGACATACGTCACCCAGACGTCATGCGCATTGCGCCAGCACCGCTGTACAACTCGTTCGCGGACGTACATCGATTTATATCCATGCTCAATGCCGCCTTTAAAACCATCACTCCGAATAGCTGAGTAACAACGCCTGTCATTTGAAACAGTCACATAGGAAGCTTAATGGCCCTACTTTGAAAGCGTCACATAAGAGAGCTTAGTAATCCTGCATTCGTCACTTGAAGCCGCTGATTTACCGATCAAGGCTTAGGACCTCTATACTACATAGGCAACGATAAAAGAGCTAAGTAGCCTAGCCTTTGAGTGGGCCACTATGAAAAGCTAAGTAACCTCGTGATGCATGTGTGATTCATAGCGGTATCAATATTTGTGTGTTGGAGAGGGAACTCTGATTTTACATTATAGAGCCCTTTGTTATATTATACGATTGTGCTAAATGGCTCTTTTTATAGGGGCACATGTCATTATCCGTTGGTACACCATAGaacaatttcttttttctttttcttcttttcatgGATGGGCTTTAGCCAAATTGAACGTTCACGCACCAAGACTTGTAAATGTAATTTATCCTGTTCTTTTAGTCCTACGAGTTAAAGATGGTGTCGTAATGTTAAAGAAGTAACTTTTATTACCCCGTGGTAGAACGGTAGACTATTTTACATAGTTTCAAAAGCTATTTTAGAATAGACCTAACattaaaacaattaaaatttcCATGTCGTAAAACATTGTCATGTGAAGGCGGTAGCTAGTAAAGTGTTCCCCCTGCTGAATTGAAACATGTGAAACAAGTGATAAAAGAGAGCATATGGAGGTGTGATTTTACAATTCTGAATATAATAAATAGCCTATTCTTCTAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
A7SCH8	Kynureninase OS=Nematostella vectensis OX=45351 GN=kynu PE=3 SV=1
Q9CXF0	Kynureninase OS=Mus musculus OX=10090 GN=Kynu PE=1 SV=3
P70712	Kynureninase OS=Rattus norvegicus OX=10116 GN=Kynu PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003133 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00266 all species →	Aminotran_5	Aminotransferase class-V	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR015424 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase	Interproscan
IPR010111 all species →	Family	Kynureninase	Interproscan
IPR015421 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase, major domain	Interproscan
IPR015422 all species →	Homologous_superfamily	Pyridoxal phosphate-dependent transferase, small domain	Interproscan
IPR000192 all species →	Domain	Aminotransferase class V domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR14084 all species →	KYNURENINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006569 all species →	Biological Process	tryptophan catabolic process	Interproscan
GO:0009435 all species →	Biological Process	NAD biosynthetic process	Interproscan
GO:0019441 all species →	Biological Process	tryptophan catabolic process to kynurenine	Interproscan
GO:0030170 all species →	Molecular Function	pyridoxal phosphate binding	Interproscan
GO:0030429 all species →	Molecular Function	kynureninase activity	Interproscan
GO:0043420 all species →	Biological Process	anthranilate metabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01556	KYNU, kynU; kynureninase	EC:3.7.1.3	Tryptophan metabolism	ko00380	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032235183.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

44TPM > 0

16Conditions

40.4Max TPM

24.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole 6 week old aboral regenerate · regenerate 96hpa	3	3	23.62	27.87
whole 6 week old aboral regenerate · regenerate 144hpa	3	3	22.40	29.70
whole 6 week old aboral regenerate · regenerate 0hpa	3	3	28.99	31.49
whole 6 week old aboral regenerate · regenerate 2hpa	3	3	28.51	29.64
whole 6 week old aboral regenerate · regenerate uncut	3	3	25.70	28.31
whole 6 week old aboral regenerate · regenerate 4hpa	3	3	22.28	23.12
whole 6 week old aboral regenerate · regenerate 120hpa	3	2	18.81	28.93
whole 6 week old aboral regenerate · regenerate 36hpa	3	3	28.44	30.89
whole 6 week old aboral regenerate · regenerate 24hpa	3	2	16.11	26.83
whole 6 week old aboral regenerate · regenerate 20hpa	3	3	23.76	26.27
whole 6 week old aboral regenerate · regenerate 16hpa	3	3	25.21	26.44
whole 6 week old aboral regenerate · regenerate 72hpa	3	3	32.76	40.43
whole 6 week old aboral regenerate · regenerate 60hpa	3	3	28.56	31.14
whole 6 week old aboral regenerate · regenerate 48hpa	3	2	19.63	31.91
whole 6 week old aboral regenerate · regenerate 8hpa	3	3	23.28	29.47
whole 6 week old aboral regenerate · regenerate 12hpa	3	2	17.64	28.24

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6320836	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	27.87
SRR6320837	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	22.23
SRR6320863	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	20.75
SRR6320847	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	29.70
SRR6320841	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	20.14
SRR6320838	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	17.35
SRR6320840	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	31.49
SRR6320846	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	29.21
SRR6320839	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	26.27
SRR6320861	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	29.64
SRR6320842	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	28.79
SRR6320848	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	27.11
SRR6320843	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	28.31
SRR6320844	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	25.54
SRR6320845	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	23.23
SRR6320873	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	23.12
SRR6320849	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	22.85
SRR6320872	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	20.87
SRR6320882	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	28.93
SRR6320883	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	27.50
SRR6320850	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	0.00
SRR6320855	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	30.89
SRR6320851	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	30.61
SRR6320852	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	23.81
SRR6320854	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	26.83
SRR6320853	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	21.50
SRR6320856	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	0.00
SRR6320859	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	26.27
SRR6320860	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	22.56
SRR6320857	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	22.45
SRR6320880	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	26.44
SRR6320858	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	25.22
SRR6320881	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	23.98
SRR6320864	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	40.43
SRR6320862	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	32.38
SRR6320865	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	25.49
SRR6320867	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	31.14
SRR6320866	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	27.45
SRR6320869	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	27.08
SRR6320870	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	31.91
SRR6320871	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	26.98
SRR6320868	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320874	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	29.47
SRR6320875	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	25.26
SRR6320876	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	15.11
SRR6320877	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	28.24
SRR6320879	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	24.70
SRR6320878	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.