Genomic Location: NC_064042.1:5280279...5287737
NR annotation: XP_032236077.2, hormone-sensitive lipase [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5511001 |
| Transcript |
| rna-XM_032380186.2 |
| Protein |
| XP_032236077.2 |
| UniProt accession | Description |
|---|---|
| Q9R101 | Hormone-sensitive lipase OS=Ictidomys tridecemlineatus OX=43179 GN=LIPE PE=2 SV=1 |
| P54310 | Hormone-sensitive lipase OS=Mus musculus OX=10090 GN=Lipe PE=1 SV=2 |
| Q68J42 | Hormone-sensitive lipase OS=Sus scrofa OX=9823 GN=LIPE PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0006016 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF06350 all species → | HSL_N | Hormone-sensitive lipase (HSL) N-terminus | Family | Interproscan |
| PF07859 all species → | Abhydrolase_3 | alpha/beta hydrolase fold | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR029058 all species → | Homologous_superfamily | Alpha/Beta hydrolase fold | Interproscan |
| IPR010468 all species → | Domain | Hormone-sensitive lipase, N-terminal | Interproscan |
| IPR002168 all species → | Active_site | Lipase, GDXG, putative histidine active site | Interproscan |
| IPR013094 all species → | Domain | Alpha/beta hydrolase fold-3 | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23025 all species → | TRIACYLGLYCEROL LIPASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004771 all species → | Molecular Function | sterol ester esterase activity | Interproscan |
| GO:0004806 all species → | Molecular Function | triacylglycerol lipase activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0019433 all species → | Biological Process | triglyceride catabolic process | Interproscan |
| GO:0008203 all species → | Biological Process | cholesterol metabolic process | Interproscan |
| GO:0016042 all species → | Biological Process | lipid catabolic process | Interproscan |
| GO:0016298 all species → | Molecular Function | lipase activity | Interproscan |
| GO:0016787 all species → | Molecular Function | hydrolase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K07188 | LIPE, HSL; hormone-sensitive lipase | EC:3.1.1.79 | Thermogenesis | ko04714 | deepkoala |
Transcript abundance of XP_032236077.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 4.57 | 6.38 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 3.59 | 5.23 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 4.31 | 4.76 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 4.06 | 5.12 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 2.99 | 3.73 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 1 | 1.41 | 4.22 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 3.46 | 5.76 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 4.03 | 4.94 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 2.64 | 4.50 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 3.28 | 3.50 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 3.11 | 3.55 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 2 | 2.90 | 4.54 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 4.08 | 4.86 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 1 | 1.71 | 5.13 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 2.99 | 5.34 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 1.31 | 3.93 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.