Genomic Location: NC_064043.1:1471876...1482998
NR annotation: XP_032237408.2, ubiquitin-protein ligase E3A isoform X2 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5512130 |
| Transcript |
| rna-XM_032381517.2 |
| Protein |
| XP_032237408.2 |
| UniProt accession | Description |
|---|---|
| Q05086 | Ubiquitin-protein ligase E3A OS=Homo sapiens OX=9606 GN=UBE3A PE=1 SV=4 |
| O08759 | Ubiquitin-protein ligase E3A OS=Mus musculus OX=10090 GN=Ube3a PE=1 SV=2 |
| Q8CDU6 | Probable E3 ubiquitin-protein ligase HECTD2 OS=Mus musculus OX=10090 GN=Hectd2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004925 (this species only) |
| Ubiquitin family | E3|E3 activity|HECT · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00632 all species → | HECT | HECT-domain (ubiquitin-transferase) | Domain | Interproscan |
| PF16558 all species → | AZUL | Amino-terminal Zinc-binding domain of ubiquitin ligase E3A | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR042556 all species → | Homologous_superfamily | Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily | Interproscan |
| IPR035983 all species → | Homologous_superfamily | HECT, E3 ligase catalytic domain | Interproscan |
| IPR000569 all species → | Domain | HECT domain | Interproscan |
| IPR044611 all species → | Family | Ubiquitin-protein ligase E3A/B/C-like | Interproscan |
| IPR032353 all species → | Domain | Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45700 all species → | UBIQUITIN-PROTEIN LIGASE E3C | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0000209 all species → | Biological Process | protein polyubiquitination | Interproscan |
| GO:0006511 all species → | Biological Process | ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0061630 all species → | Molecular Function | ubiquitin protein ligase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10587 | UBE3A, E6AP; ubiquitin-protein ligase E3 A | EC:2.3.2.26 | Ubiquitin system | ko04121 | deepkoala |
Transcript abundance of XP_032237408.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 17.89 | 20.41 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 15.61 | 17.62 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 16.83 | 17.92 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 16.43 | 18.60 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 15.44 | 16.31 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 3 | 19.30 | 26.50 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 19.98 | 23.16 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 20.76 | 26.30 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 21.03 | 22.00 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 21.85 | 22.70 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 19.47 | 20.72 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 21.97 | 28.18 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 17.24 | 18.70 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 3 | 21.20 | 22.00 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 13.38 | 21.23 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 3 | 22.58 | 32.33 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.