Genomic Location: NC_064036.1:3998108...4005594
NR annotation: XP_032239660.2, mitofusin-2 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5514215 |
| Transcript |
| rna-XM_032383769.2 |
| Protein |
| XP_032239660.2 |
| UniProt accession | Description |
|---|---|
| Q80U63 | Mitofusin-2 OS=Mus musculus OX=10090 GN=Mfn2 PE=1 SV=3 |
| Q8R500 | Mitofusin-2 OS=Rattus norvegicus OX=10116 GN=Mfn2 PE=1 SV=1 |
| O95140 | Mitofusin-2 OS=Homo sapiens OX=9606 GN=MFN2 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003171 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF04799 all species → | Fzo_mitofusin | fzo-like conserved region | Family | Interproscan |
| PF00350 all species → | Dynamin_N | Dynamin family | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR030381 all species → | Domain | Dynamin-type guanine nucleotide-binding (G) domain | Interproscan |
| IPR006884 all species → | Domain | Fzo/mitofusin HR2 domain | Interproscan |
| IPR027094 all species → | Family | Mitofusin family | Interproscan |
| IPR045063 all species → | Domain | Dynamin, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10465 all species → | TRANSMEMBRANE GTPASE FZO1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005525 all species → | Molecular Function | GTP binding | Interproscan |
| GO:0003924 all species → | Molecular Function | GTPase activity | Interproscan |
| GO:0005741 all species → | Cellular Component | mitochondrial outer membrane | Interproscan |
| GO:0008053 all species → | Biological Process | mitochondrial fusion | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0031306 all species → | Cellular Component | obsolete intrinsic component of mitochondrial outer membrane | Interproscan |
| GO:0051646 all species → | Biological Process | mitochondrion localization | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06030 | MFN2, FZO1; mitofusin 2 | EC:3.6.5.- | Mitochondrial biogenesis | ko03029 | deepkoala |
Transcript abundance of XP_032239660.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 11.08 | 13.09 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 7.86 | 9.97 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 8.01 | 8.59 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 12.06 | 15.52 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 7.00 | 7.98 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 8.50 | 13.78 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 6.73 | 11.30 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 12.27 | 14.20 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 13.09 | 15.03 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 14.75 | 19.80 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 10.17 | 12.42 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 14.88 | 21.97 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 12.02 | 13.10 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 7.05 | 13.47 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 6.69 | 10.33 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 3.79 | 11.36 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.