Genomic Location: NC_064040.1:4110931...4113440
NR annotation: XP_032240405.2, rRNA N6-adenosine-methyltransferase METTL5 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC116619589 |
| Transcript |
| rna-XM_032384514.2 |
| Protein |
| XP_032240405.2 |
| UniProt accession | Description |
|---|---|
| Q9NRN9 | rRNA N(6)-adenosine-methyltransferase METTL5 OS=Homo sapiens OX=9606 GN=METTL5 PE=1 SV=1 |
| F1QVR8 | rRNA N(6)-adenosine-methyltransferase METTL5 OS=Danio rerio OX=7955 GN=mettl5 PE=2 SV=1 |
| Q8K1A0 | rRNA N(6)-adenosine-methyltransferase METTL5 OS=Mus musculus OX=10090 GN=Mettl5 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0008392 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF05175 all species → | MTS | Methyltransferase small domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002052 all species → | Conserved_site | DNA methylase, N-6 adenine-specific, conserved site | Interproscan |
| IPR029063 all species → | Homologous_superfamily | S-adenosyl-L-methionine-dependent methyltransferase superfamily | Interproscan |
| IPR051720 all species → | Family | rRNA N6-Adenosine-Methyltransferase/Polyamine Synthase | Interproscan |
| IPR007848 all species → | Domain | Methyltransferase small domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23290 all species → | UNCHARACTERIZED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003676 all species → | Molecular Function | nucleic acid binding | Interproscan |
| GO:0008168 all species → | Molecular Function | methyltransferase activity | Interproscan |
| GO:0032259 all species → | Biological Process | methylation | Interproscan |
| GO:0008988 all species → | Molecular Function | rRNA (adenine-N6-)-methyltransferase activity | Interproscan |
| GO:0016740 all species → | Molecular Function | transferase activity | Interproscan |
| GO:0031167 all species → | Biological Process | rRNA methylation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K24418 | METTL5; rRNA N6-adenosine-methyltransferase METTL5 | - | Ribosome biogenesis | ko03009 | deepkoala |
Transcript abundance of XP_032240405.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 5.61 | 6.37 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 4.20 | 4.94 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 2.91 | 3.28 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 3.71 | 4.44 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 3.64 | 3.98 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 1 | 1.65 | 4.95 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 3.16 | 5.12 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 6.43 | 8.42 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 3.15 | 4.96 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 2 | 2.52 | 4.08 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 4.19 | 4.45 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 2 | 3.55 | 5.92 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 2 | 3.46 | 5.50 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 1 | 2.10 | 6.31 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 3.51 | 5.75 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 1.08 | 3.24 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.