Genomic Location: NC_064040.1:3663982...3667027
NR annotation: XP_032240462.2, E3 ubiquitin-protein ligase RNF216 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5514953 |
| Transcript |
| rna-XM_032384571.2 |
| Protein |
| XP_032240462.2 |
| UniProt accession | Description |
|---|---|
| P58283 | E3 ubiquitin-protein ligase RNF216 OS=Mus musculus OX=10090 GN=Rnf216 PE=1 SV=3 |
| Q9NWF9 | E3 ubiquitin-protein ligase RNF216 OS=Homo sapiens OX=9606 GN=RNF216 PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0007151 (this species only) |
| Ubiquitin family | E3|E3 activity|RBR · all ubiquitin genes in this species |
XP_032240462.2. This gene does have a gene model — the search simply returned no hit.| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR047544 all species → | Domain | E3 ubiquitin-protein ligase RNF216, RING finger, HC subclass | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR047546 all species → | Domain | E3 ubiquitin-protein ligase RNF216, Rcat domain | Interproscan |
| IPR044066 all species → | Domain | TRIAD supradomain | Interproscan |
| IPR051628 all species → | Family | Linear Ubiquitination-Associated E3 Ligases | Interproscan |
| IPR047545 all species → | Domain | E3 ubiquitin-protein ligase RNF216, BRcat domain | Interproscan |
| IPR002867 all species → | Domain | IBR domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22770 all species → | UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000151 all species → | Cellular Component | ubiquitin ligase complex | Interproscan |
| GO:0004842 all species → | Molecular Function | ubiquitin-protein transferase activity | Interproscan |
| GO:0043130 all species → | Molecular Function | ubiquitin binding | Interproscan |
| GO:0043161 all species → | Biological Process | proteasome-mediated ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0071797 all species → | Cellular Component | LUBAC complex | Interproscan |
| GO:0097039 all species → | Biological Process | protein linear polyubiquitination | Interproscan |
| GO:0008270 all species → | Molecular Function | zinc ion binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11976 | RNF216, TRIAD3; E3 ubiquitin-protein ligase RNF216 | EC:2.3.2.31 | Ubiquitin system | ko04121 | deepkoala |
Transcript abundance of XP_032240462.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 3.16 | 5.07 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 1.94 | 2.58 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 3.11 | 3.51 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 2.10 | 2.59 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 1.97 | 2.21 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 3 | 4.02 | 7.91 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 2.19 | 3.39 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 2.53 | 2.67 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 1.93 | 2.19 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 1.80 | 2.44 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 1.48 | 2.04 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 3.01 | 3.48 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 2.72 | 3.64 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 1.55 | 2.65 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 2.01 | 2.19 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 3 | 3.08 | 5.02 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
