Gene detail

Detailed information of XP_032240486.1 in Nematostella vectensis

Genomic Location: NC_064039.1:7055916...7065733
NR annotation: XP_032240485.1, hexokinase-2 isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_032384595.2

AAACGAACCAACAAGAAAAGAAGACTTATTCGTCTTAGAAGAGCGAGTGTATTTATTTGAGATAACAGTCATCAGCTATTTATCAGACGGGAATTGAAAGCCTATTTATTTGAATTAAGAGAATAACGTATACATCGTACGACTCTACATAATTTattAATCATGTTCAGTGTGATTCCATTGTTATCGGGTGCCGTCAAGACTCTGAATATAACATTCAGAAGTAAAGAATTTGCACAAGAAATTCTTAAACAATATGACATGCCAAAATCATCCCTGGAGCAAGTAATGAAGCTCTTAGAAGAAGACATGGATAATGGACTCTCAGCAGACCCTAAAGCCAGGGAAAACTCACCAATTAAAATGCTTCCTACATATGTACGCAGAATGCCAGATGGTTCCGAATCAGGAGATTTTTTAGCCTTAGACCTTGGTGGCACGAACTTTAGAGTTCTTCTTGTTCAAGTACTAAATGGCAAAGTTCACATGGAGAGCGAGATCTTTCCCCTTGATCAAACACTCATGACAAGTGATTCCATCACTCTGTTTGACTATATTGCAGACTGTATTACACTGTTTGTCAAGAAGAAGTCCCTACAGGACAAGACTCTTCCCTTAGGGTTTACGTTCTCATTCCCTGTGCAACAGCTTAGTCTAACATCAGGACTGTTGATAAGGTGGACCAAGGGGTTTTCTGCGGGTGGAGTTGAGGGTGAAGATGTGGTCAGGTTGCTGAAGGATGCTCTTCACAGGAAGAATAGCCATAGTGTAGATGTGGTTGCCCTAGTCAATGATACTACTGGTACAATGATGGCATGTGGTTTTGATGATCGCAATGTGATTGCTGGATTAATCCTTGGCACAGGAACCAATGCATGTTACATGGAGAGCTTGGACAATGTGAAAAAATGGAATGAGGAGAGAGGGTGCAGTAATGAAGTGATCATTAACACCGAGTGGGGAGCATTTGGTGACAGTGGTGTGCTGAACTGGATAATAACAGAGCATGACAAGAAGATCGACGTCGAGTCCATCAACCCAGGCCAGCAAGTGTTTGAGAAGATGATATCTGGTATGTATCTTGGGGAGCTGGCTCGTCATATCTGTATGGATCTTATTCATAGAGGTCTCTTACTCAATGGTATTGCTTCAAACAAGTTAAAGACAAAAGGGAGTTTCCTCACCAAGTTTGTGTCAGATATTGAGAGTGGAGATGAAAACAAGCTTCAACAAGTTCTAAAAGAACTGGATGTCAAGGCTACTGCACGTGACCAAGAAATCCTGAGGCACATTTGCACTGCAGTGTCTAAGAGAGCTGCCAGGCTGGCCTCAGCTGGTCTTGCTACCATCGTCAAGAAAACAAAGGCATATAATAGCACTATTGCTATAGATGGTACCTTGTTCAAAAAGCACCCCAAGTTCAAGCCCTACATGCAGGAAGCTCTAAAAGAACTTTTGCCAGACAGCCACCTGAAGCTCATGCTGTCTGAGGATGGATCAGGGAAGGGAGCTGCTTTGATTGCAGCAGTTGCAGCGCACACGAAGTCCCACTAGACTAGGGGTACTTAGAGTTAGGGAATTTCAGGGAACtgctttttagaaaaaaaattcactcGAAGTCCCACTAGATTATAAAAATGTACACAATTGGGCGCGAGCCAGGATTTGTCGAGGCATTGGCATAAATACAGTAGCTTAtctaatttgaaaaaaatatacggaaaaaaaaaactcgagtCTATGGTTTGGTGATTCTCCTAGCAAAAAGACCACATGGCCACACGCCTGCTCATTTGTACGTCTGTTTTCATATGGAGTTTCATACTTCTACAATATCTTGAAATTTTTTGGAGCTTTTTTATGTAATTGAACATATAggaatgtatatatatataaatgtaGCATGGGCATATTCAGACTTTGGTATGAGTATTAGAAAACTATGACTATACGTTtttgatacttttttttaacggAAAGAAAAAGAGGGAACCGGCGGTGATGTATGCAGAGACTTTTTGTATTCGAACAGTATGATAATGCATGCACAAGAGGAAAACAGACAAAAAGTTAGTTTccagtgttggtgatggttgtTTCTGCCCTCGCTGGAAATGAAACCTGGTTTGATTGCTTACCAAGCCTGGTTTGATTGCTTACCCAGCCTAGTTTGACGGCTTACCTAGCCTTAATGTATCCATCATATATCAATGTTCAATTGGACGTCAGCCGAAATTTGACAATAAACATACTATTTACAAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P52789	Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2
A2PYL8	Hexokinase-2 OS=Equus grevyi OX=9792 GN=HK2 PE=2 SV=1
A2PYL7	Hexokinase-2 OS=Equus zebra OX=9791 GN=HK2 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0002472 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00349 all species →	Hexokinase_1	Hexokinase	Domain	Interproscan
PF03727 all species →	Hexokinase_2	Hexokinase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR019807 all species →	Binding_site	Hexokinase, binding site	Interproscan
IPR022672 all species →	Domain	Hexokinase, N-terminal	Interproscan
IPR001312 all species →	Family	Hexokinase	Interproscan
IPR043129 all species →	Homologous_superfamily	ATPase, nucleotide binding domain	Interproscan
IPR022673 all species →	Domain	Hexokinase, C-terminal	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR19443 all species →	HEXOKINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006096 all species →	Biological Process	glycolytic process	Interproscan
GO:0005975 all species →	Biological Process	carbohydrate metabolic process	Interproscan
GO:0016773 all species →	Molecular Function	phosphotransferase activity, alcohol group as acceptor	Interproscan
GO:0001678 all species →	Biological Process	intracellular glucose homeostasis	Interproscan
GO:0004340 all species →	Molecular Function	glucokinase activity	Interproscan
GO:0004396 all species →	Molecular Function	hexokinase activity	Interproscan
GO:0005536 all species →	Molecular Function	D-glucose binding	Interproscan
GO:0005739 all species →	Cellular Component	mitochondrion	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0006006 all species →	Biological Process	glucose metabolic process	Interproscan
GO:0008865 all species →	Molecular Function	fructokinase activity	Interproscan
GO:0046835 all species →	Biological Process	carbohydrate phosphorylation	Interproscan
GO:0051156 all species →	Biological Process	glucose 6-phosphate metabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00844	HK; hexokinase	EC:2.7.1.1	Glycolysis / Gluconeogenesis	ko00010	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032240486.1 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

48TPM > 0

16Conditions

612.6Max TPM

473.4Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole 6 week old aboral regenerate · regenerate 96hpa	3	3	433.48	492.03
whole 6 week old aboral regenerate · regenerate 144hpa	3	3	412.04	504.33
whole 6 week old aboral regenerate · regenerate 0hpa	3	3	583.47	612.58
whole 6 week old aboral regenerate · regenerate 2hpa	3	3	532.44	552.46
whole 6 week old aboral regenerate · regenerate uncut	3	3	491.95	523.00
whole 6 week old aboral regenerate · regenerate 4hpa	3	3	489.08	550.10
whole 6 week old aboral regenerate · regenerate 120hpa	3	3	458.03	485.18
whole 6 week old aboral regenerate · regenerate 36hpa	3	3	438.22	479.73
whole 6 week old aboral regenerate · regenerate 24hpa	3	3	436.36	462.07
whole 6 week old aboral regenerate · regenerate 20hpa	3	3	455.11	478.19
whole 6 week old aboral regenerate · regenerate 16hpa	3	3	496.21	522.49
whole 6 week old aboral regenerate · regenerate 72hpa	3	3	445.51	476.21
whole 6 week old aboral regenerate · regenerate 60hpa	3	3	421.35	423.73
whole 6 week old aboral regenerate · regenerate 48hpa	3	3	465.08	506.59
whole 6 week old aboral regenerate · regenerate 8hpa	3	3	506.99	543.55
whole 6 week old aboral regenerate · regenerate 12hpa	3	3	509.45	548.84

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6320863	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	492.03
SRR6320836	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	421.53
SRR6320837	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	386.90
SRR6320847	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	504.33
SRR6320841	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	383.85
SRR6320838	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	347.94
SRR6320846	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	612.58
SRR6320840	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	586.67
SRR6320839	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	551.15
SRR6320842	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	552.46
SRR6320861	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	540.70
SRR6320848	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	504.15
SRR6320843	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	523.00
SRR6320845	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	507.19
SRR6320844	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	445.64
SRR6320849	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	550.10
SRR6320872	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	496.28
SRR6320873	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	420.85
SRR6320882	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	485.18
SRR6320850	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	451.87
SRR6320883	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	437.05
SRR6320851	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	479.73
SRR6320855	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	430.53
SRR6320852	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	404.40
SRR6320854	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	462.07
SRR6320853	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	426.48
SRR6320856	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	420.53
SRR6320860	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	478.19
SRR6320859	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	460.47
SRR6320857	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	426.69
SRR6320881	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	522.49
SRR6320880	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	503.63
SRR6320858	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	462.51
SRR6320862	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	476.21
SRR6320864	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	457.35
SRR6320865	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	402.98
SRR6320869	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	423.73
SRR6320867	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	422.91
SRR6320866	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	417.43
SRR6320868	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	506.59
SRR6320870	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	456.23
SRR6320871	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	432.43
SRR6320874	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	543.55
SRR6320875	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	517.03
SRR6320876	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	460.39
SRR6320878	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	548.84
SRR6320877	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	513.77
SRR6320879	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	465.73

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.