Genomic Location: NC_064039.1:14683842...14699523
NR annotation: XP_032240642.2, mitochondrial proton/calcium exchanger protein [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5515135 |
| Transcript |
| rna-XM_032384751.2 |
| Protein |
| XP_032240642.2 |
| UniProt accession | Description |
|---|---|
| Q5ZK33 | Mitochondrial proton/calcium exchanger protein OS=Gallus gallus OX=9031 GN=LETM1 PE=2 SV=1 |
| O95202 | Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1 |
| Q5XIN6 | Mitochondrial proton/calcium exchanger protein OS=Rattus norvegicus OX=10116 GN=Letm1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005050 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF07766 all species → | LETM1_RBD | LETM1-like, RBD | Domain | Interproscan |
| PF13499 all species → | EF-hand_7 | EF-hand domain pair | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR033122 all species → | Domain | LETM1-like, ribosome-binding domain | Interproscan |
| IPR002048 all species → | Domain | EF-hand domain | Interproscan |
| IPR011992 all species → | Homologous_superfamily | EF-hand domain pair | Interproscan |
| IPR044202 all species → | Family | LETM1/MDM38-like | Interproscan |
| IPR018247 all species → | Binding_site | EF-Hand 1, calcium-binding site | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR14009 all species → | LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0043022 all species → | Molecular Function | ribosome binding | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0005743 all species → | Cellular Component | mitochondrial inner membrane | Interproscan |
| GO:0006875 all species → | Biological Process | obsolete intracellular metal ion homeostasis | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K17800 | LETM1, MDM38; LETM1 and EF-hand domain-containing protein 1, mitochondrial | - | Transporters | ko02000 | deepkoala |
Transcript abundance of XP_032240642.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 37.80 | 41.10 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 26.56 | 31.85 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 44.50 | 55.45 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 49.94 | 59.04 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 30.06 | 32.60 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 3 | 46.41 | 49.10 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 34.54 | 39.64 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 36.60 | 40.50 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 23.45 | 36.32 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 35.46 | 39.30 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 32.27 | 34.88 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 34.41 | 41.12 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 35.97 | 38.28 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 3 | 39.46 | 41.64 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 32.25 | 36.63 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 3 | 32.41 | 41.47 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.