Genomic Location: NC_064039.1:14631434...14653073
NR annotation: XP_032240678.2, phosphatidylinositide phosphatase SAC2 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5515138 |
| Transcript |
| rna-XM_032384787.2 |
| Protein |
| XP_032240678.2 |
| UniProt accession | Description |
|---|---|
| A8E7C5 | Phosphatidylinositide phosphatase SAC2 OS=Danio rerio OX=7955 GN=inpp5f PE=3 SV=1 |
| Q9Y2H2 | Phosphatidylinositide phosphatase SAC2 OS=Homo sapiens OX=9606 GN=INPP5F PE=1 SV=3 |
| Q8CDA1 | Phosphatidylinositide phosphatase SAC2 OS=Mus musculus OX=10090 GN=Inpp5f PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004344 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12456 all species → | hSac2 | Inositol phosphatase | Domain | Interproscan |
| PF02383 all species → | Syja_N | SacI homology domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002013 all species → | Domain | SAC domain | Interproscan |
| IPR022158 all species → | Domain | Inositol phosphatase | Interproscan |
| IPR034753 all species → | Domain | hSac2 domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45662 all species → | PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0016791 all species → | Molecular Function | phosphatase activity | Interproscan |
| GO:0005769 all species → | Cellular Component | early endosome | Interproscan |
| GO:0043812 all species → | Molecular Function | phosphatidylinositol-4-phosphate phosphatase activity | Interproscan |
| GO:0045334 all species → | Cellular Component | clathrin-coated endocytic vesicle | Interproscan |
| GO:0046856 all species → | Biological Process | phosphatidylinositol dephosphorylation | Interproscan |
| GO:2001135 all species → | Biological Process | regulation of endocytic recycling | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K21798 | SAC2, INPP5F; phosphatidylinositol 4-phosphatase | EC:3.1.3.- | Phosphatidylinositol signaling system | ko04070 | deepkoala |
Transcript abundance of XP_032240678.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 8.06 | 8.34 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 6.79 | 9.37 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 7.07 | 8.09 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 8.27 | 10.66 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 5.95 | 6.55 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 4.70 | 8.59 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 8.84 | 9.24 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 8.19 | 9.59 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 5.85 | 10.20 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 9.10 | 9.38 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 8.69 | 9.53 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 2 | 5.77 | 9.29 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 2 | 5.43 | 8.79 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 5.96 | 10.67 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 5.73 | 8.83 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 3.41 | 10.24 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.