Genomic Location: NC_064035.1:17217164...17227688
NR annotation: XP_032241468.2, ceramide synthase 6 isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5515822 |
| Transcript |
| rna-XM_032385577.2 |
| Protein |
| XP_032241468.2 |
| UniProt accession | Description |
|---|---|
| Q6ZMG9 | Ceramide synthase 6 OS=Homo sapiens OX=9606 GN=CERS6 PE=1 SV=1 |
| Q8C172 | Ceramide synthase 6 OS=Mus musculus OX=10090 GN=Cers6 PE=1 SV=1 |
| Q9D6K9 | Ceramide synthase 5 OS=Mus musculus OX=10090 GN=Cers5 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0002351 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03798 all species → | TRAM_LAG1_CLN8 | TLC domain | Domain | Interproscan |
| PF00046 all species → | Homeodomain | Homeodomain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006634 all species → | Domain | TRAM/LAG1/CLN8 homology domain | Interproscan |
| IPR001356 all species → | Domain | Homeobox domain | Interproscan |
| IPR009057 all species → | Homologous_superfamily | Homeobox-like domain superfamily | Interproscan |
| IPR016439 all species → | Family | Sphingosine N-acyltransferase Lag1/Lac1-like | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12560 all species → | LONGEVITY ASSURANCE FACTOR 1 LAG1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0046513 all species → | Biological Process | ceramide biosynthetic process | Interproscan |
| GO:0050291 all species → | Molecular Function | sphingosine N-acyltransferase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K23727 | CERS5_6, LASS5_6; sphingoid base N-palmitoyltransferase | EC:2.3.1.291 | Sphingolipid signaling pathway | ko04071 | deepkoala |
Transcript abundance of XP_032241468.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 33.60 | 40.12 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 24.82 | 31.46 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 20.01 | 21.37 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 24.26 | 28.82 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 20.20 | 23.48 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 19.43 | 34.49 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 29.73 | 32.80 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 27.79 | 32.64 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 24.93 | 26.82 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 21.08 | 23.97 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 24.44 | 27.68 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 34.47 | 39.29 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 31.48 | 34.05 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 17.67 | 31.37 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 23.47 | 27.51 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 2 | 21.50 | 39.68 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.