Genomic Location: NC_064034.1:12846759...12861504
NR annotation: XP_032241525.2, cyclin-G-associated kinase isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5515943 |
| Transcript |
| rna-XM_032385634.2 |
| Protein |
| XP_032241525.2 |
| UniProt accession | Description |
|---|---|
| Q99KY4 | Cyclin-G-associated kinase OS=Mus musculus OX=10090 GN=Gak PE=1 SV=2 |
| P97874 | Cyclin-G-associated kinase OS=Rattus norvegicus OX=10116 GN=Gak PE=1 SV=1 |
| O14976 | Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004163 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00069 all species → | Pkinase | Protein kinase domain | Domain | Interproscan |
| PF00102 all species → | Y_phosphatase | Protein-tyrosine phosphatase | Domain | Interproscan |
| PF10409 all species → | PTEN_C2 | C2 domain of PTEN tumour-suppressor protein | Domain | Interproscan |
| PF00226 all species → | DnaJ | DnaJ domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR029021 all species → | Homologous_superfamily | Protein-tyrosine phosphatase-like | Interproscan |
| IPR035892 all species → | Homologous_superfamily | C2 domain superfamily | Interproscan |
| IPR000719 all species → | Domain | Protein kinase domain | Interproscan |
| IPR036869 all species → | Homologous_superfamily | Chaperone J-domain superfamily | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR001623 all species → | Domain | DnaJ domain | Interproscan |
| IPR000242 all species → | Domain | Tyrosine-specific protein phosphatase, PTPase domain | Interproscan |
| IPR014020 all species → | Domain | Tensin phosphatase, C2 domain | Interproscan |
| IPR008271 all species → | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR029023 all species → | Domain | Tensin-type phosphatase domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22967 all species → | SERINE/THREONINE PROTEIN KINASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004672 all species → | Molecular Function | protein kinase activity | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0004674 all species → | Molecular Function | protein serine/threonine kinase activity | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0035612 all species → | Molecular Function | AP-2 adaptor complex binding | Interproscan |
| GO:0045747 all species → | Biological Process | positive regulation of Notch signaling pathway | Interproscan |
| GO:2000369 all species → | Biological Process | regulation of clathrin-dependent endocytosis | Interproscan |
| GO:0004725 all species → | Molecular Function | protein tyrosine phosphatase activity | Interproscan |
| GO:0006470 all species → | Biological Process | protein dephosphorylation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K08855 | GAK; cyclin G-associated kinase | EC:2.7.11.1 | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of XP_032241525.2 across 48 RNA-seq samples of Nematostella vectensis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
