Gene detail

Detailed information of XP_032241691.2 in Nematostella vectensis

Genomic Location: NC_064040.1:16795747...16806451
NR annotation: XP_032241691.2, denticleless protein homolog [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

LOC5515998

ATGACGCTATTGTACTCCATCTTACACCGAGAACTTGTGTGTAATTCTCCAAGAAAGCAAATCTCCCTGGATTTCGCCCTAGATTCTTTTGTATGTCATCGAGTAGATGAACATCCTATTCACGGCAAAGATTCAGGGGTTGAAGTTCCACCATTCGCGAGCAGTTTTAGCAAGAATGCTGGAGATAAACACCACTTAGCTGTGGCAGACGAAGATGGATCCGTTCGAGTACTGGACACAAATAAATACGGACGACAAGCTATTGTTGTTGAGTGGACAGCACACTCAAATGCCATCTTTGATGTTGCCTGGATGCACAATGAAGCAAAACTTGTCACTGCTTCAGGAGATCAAACAGCAAGGCTCTGGGACGTCACCAAGGAGACAAGCTTGGCTGTATTCAAAGGCCATAGCTGTAGCCTTAAGTCAGTTGACTTCAGAAAAAATGACCAGTTTACATTTGCTACTGGTGCTAGAGATGGAAATATTATGGTATGGGACACAAGATGTAACCAGCGCCGAGACCACTACCAGCCTGTGAATACTATCTACAGTGCCCATACGCAGCAATTGACCACACCCATGAGAGCCCGTAAGCGTTCACGCCGAGCATCTACCCCTCAGCCAGTTACAGACTCCCAGCAAAGTGTTACAGCTGTGGTCTTCCATGGCGATAATTTGTTGATATCTGCTGGTGCCATGGATGGAAACCTGAAGATGTGGGATTTGCGCAAGTATTACACGATGGCTAAGCAGGACCCAGTGCCATACCACATGTTCCCTTATCCAGGAAAGGGTCCTAGGAAACATGGCTTCTCATCACTTGTTCTAGACTCCAACCAATCCAAGTTGTATGCTAGTTGCACAAACGATCACATCTACATGTATGAATGTTCTGTGCTTGGAGAGGATCCAGTCTGCTCATTTACTGGTCATTCAAACTCGACATTCTATGTAAAAGCTGCACTAAGTCCTGATGACAATTACCTTCTTTCTGGGTCTAGCGACAATAATGCATATATATGGAAAGTGTCTGATGCTGACAGGCCGCCAGTCTGTCTTAGGGGTCACGCTGGTGAGGTGACAAGTGTCGTATGGTGCCCTCAAGACATAACTAAGGTTGTCACATGTTCCGATGACACAACTGTAAGAATCTGGAGGATGAACCGAGGAGTTGAATTTCAAGAAAGAACAGACTATATTGGTTTCACTGAGAGAATGAAGACACAAATACAACCACATTCAACATCCAAACAAGAACAAAATGGCATGTCAACAACACCACAGAACAAGAGTGGCAGATACACTTATAAGGTCCACACAAACCCACGCCTTAATCCCTTGTCAAGCCCTGTTGCCAAGGTAACAATTAAGAGATGTAATACCCCACCCAAGAAGCTGACAATCAAGTGTGCATGCCCCACAACCCAGCCGACAAAAAGCCCTGTAAGGGCTGGGCGTACTGCTTGTCCTGTTTCCCCCCTGACCACCCCCCACATTTCAAGCTGCCCCCTCTCCCCTGGGGTATCCTCTCCAAAATGCCAAAGCCCACAACAACTTCTTAGATCCTGGCTGAAGGTAACCCCACCCAGGAAAAACTCAAATAAACATATGGATGATGTACGTGAAGAAGGCTCTAAGGGTCAAAAAAAGCAAAGTGCTATGCCACGACTGAGGAAAGGCCTTGAGAAAGCTTTATCTGAATGTGCTGTTCAGGACACCAACCAGGAGAGTAAGTTATCAATGCAAGCCTCTGATACAAGTCCATCGTTGTCTCCTGCACGCAAACGCCAATGCATTATGATGAGTTCAGAGAACAGTGATGATACTGATACTCCTTTTGCCAAAACCATGATAGTGGTACAAGACAATAAAGAGAATAGCGAACCAAAAAATCACTTTAAGGATAAGAGGATTGTTAATGCTTCTCAACATATTGGTTTTGTGGATGAGAGAGATATAAAGCATTCAAATTGGTTAACAACTTGGAGTAGATTGCAAAGGCAGAAGAATGGGAGCATAAGTGAGAATAAACAAGTCATTACTGACAACTGTAATGAAAATGGAGAGAACTGCTCACCTACAAAAGACAATGAGGATACAAATGTGACCTTTTTGGTAGCTAAACCAGAAGAGAGCATTTTGCATTATTTTAAGCCAACACTGAGTCCAATAAAGGAGTATATAAGGTAG

Transcript

rna-XM_032385800.2

atcagatttcTTTGTAGAAACGTTCGCGCGTTTTTCGATCGCAAATTTCGCGGGAGATCAAAATAACCCAAGAATTCGCCTACAATGTGCAAGTTTCTTTGCCTTTGATCGTATAATATCATCTATTTTCACATGTTCTTTCATCTGTAAGCCAACTTACATCAATATGACGCTATTGTACTCCATCTTACACCGAGAACTTGTGTGTAATTCTCCAAGAAAGCAAATCTCCCTGGATTTCGCCCTAGATTCTTTTGTATGTCATCGAGTAGATGAACATCCTATTCACGGCAAAGATTCAGGGGTTGAAGTTCCACCATTCGCGAGCAGTTTTAGCAAGAaTGCTGGAGATAAACACCACTTAGCTGTGGCAGACGAAGATGGATCCGTTCGAGTACTGGACACAAATAAATACGGACGACAAGCTATTGTTGTTGAGTGGACAGCACACTCAAATGCCATCTTTGATGTTGCCTGGATGCACAATGAAGCAAAACTTGTCACTGCTTCAGGAGATCAAACAGCAAGGCTCTGGGACGTCACCAAGGAGACAAGCTTGGCTGTATTCAAAGGCCATAGCTGTAGCCTTAAGTCAGTTGACTTCAGAAAAAATGACCAGTTTACATTTGCTACTGGTGCTAGAGATGGAAATATTATGGTATGGGACACAAGATGTAACCAGCGCCGAGACCACTACCAGCCTGTGAATACTATCTACAGTGCCCATACGCAGCAATTGACCACACCCATGAGAGCCCGTAAGCGTTCACGCCGAGCATCTACCCCTCAGCCAGTTACAGACTCCCAGCAAAGTGTTACAGCTGTGGTCTTCCATGGCGATAATTTGTTGATATCTGCTGGTGCCATGGATGGAAACCTGAAGATGTGGGATTTGCGCAAGTATTACACGATGGCTAAGCAGGACCCAGTGCCATACCACATGTTCCCTTATCCAGGAAAGGGTCCTAGGAAACATGGCTTCTCATCACTTGTTCTAGACTCCAACCAATCCAAGTTGTATGCTAGTTGCACAAACGATCACATCTACATGTATGAATGTTCTGTGCTTGGAGAGGATCCAGTCTGCTCATTTACTGGTCATTCAAACTCGACATTCTATGTAAAAGCTGCACTAAGTCCTGATGACAATTACCTTCTTTCTGGGTCTAGCGACAATAATGCATATATATGGAAAGTGTCTGATGCTGACAGGCCGCCAGTCTGTCTTAGGGGTCACGCTGGTGAGGTGACAAGTGTCGTATGGTGCCCTCAAGACATAACTAAGgTTGTCACATGTTCCGATGACACAACTGTAAGAATCTGGAGGATGAACCGAGGAGTTGAATTTCAAGAAAGAACAGACTATATTGGTTTCACTGAGAGAATGAAGACACAAATACAACCACATTCAACATccaaacaagaacaaaatggCATGTCAACAACACCACAGAACAAGAGTGGCAGATACACTTATAAGGTCCACACAAACCCACGCCTTAATCCCTTGTCAAGCCCTGTTGCCAAGGTAACAATTAAGAGATGTAATACCCCACCCAAGAAGCTGACAATCAAGTGTGCATGCCCCACAACCCAGCCGACAAAAAGCCCTGTAAGGGCTGGGCGTACTGCTTGTCCTGTTTCCCCCCTGACCACCCCCCACATTTCAAGctgccccctctcccctgGGGTATCCTCTCCAAAATGCCAAAGCCCACAACAACTTCTTAGATCCTGGCTGAAGGTAACCCCACCCAGGAAAAACTCAAATAAACATATGGATGATGTACGTGAAGAAGGCTCTAAGGGTCAAAAAAAGCAAAGTGCTATGCCACGACTGAGGAAAGGCCTTGAGAAAGCTTTATCTGAATGTGCTGTTCAGGACACCAACCAGGAGAGTAAGTTATCAATGCAAGCCTCTGATACAAGTCCATCGTTGTCTCCTGCACGCAAACGCCAATGCATTATGATGAGTTCAGAGAACAGTGATGATACTGATACTCCTTTTGCCAAAACCATGATAGTGGTACAAGACAATAAAGAGAATAGCGAACCAAAAAATCACTTTAAGGATAAGAGGATTGTTAATGCTTCTCAACATATTGGTTTTGTGGATGAGAGAGATATAAAGCATTCAAATTGGTTAACAACTTGGAGTAGATTGCAAAGGCAGAAGAATGGGAGCATAAGTGAGAATAAACAAGTCATTACTGACAACTGTAATGAAAATGGAGAGAACTGCTCACCTACAAAAGACAATGAGGATACAAATGTGACCTTTTTGGTAGCTAAACCAGAAGAGAGCATTTTGCATTATTTTAAGCCAACACTGAGTCCAATAAAGGAGTATATAAGGTAGACCTGACCAACCTCCCATCAAGCAAAGGGGAAGAAAATTAAGATACATTATGCTTAATTATAGAAGGATGTGACACACCATTGTTATTGAAAACTTAACTTTTCATACCAACTGTGATATGGAGTACCATATGGATGTGACACACCATTGTTACTGAGAACTTTACTTTTCATACCAACTGTGATATGTGAGTACCCAGTCCTCTTCACCAAGAAAAGATTAtagtttggtaaaaaaaaaagaaaaaagaaaatgaataGGTTTGAGATTCAAATTCTGTCTTGGTAATTCCTGTATTAATCAACTAACCTAGTTGTGTATAATCTTGGATGATATTCATGATAAAAATTATTAACAAACTGTGCCATATTGCTATATTGGGCACAGTGATTATGGTATAcaatgcaagaaaaaaaaatgtgcagACTGTTTTAGATTCCAAAAGATATTATTGAATAAATGTTTATAATTTACTTCa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q6GPU3	Denticleless protein homolog B OS=Xenopus laevis OX=8355 GN=dtl-b PE=2 SV=1
Q9NZJ0	Denticleless protein homolog OS=Homo sapiens OX=9606 GN=DTL PE=1 SV=3
Q3TLR7	Denticleless protein homolog OS=Mus musculus OX=10090 GN=Dtl PE=1 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0006236 (this species only)
Ubiquitin family	UBD\|Other\|Beta-prp · all ubiquitin genes in this species
Ubiquitin family	E3\|E3 adaptor Cullin RING\|CDC20 · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00400 all species →	WD40	WD domain, G-beta repeat	Repeat	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001680 all species →	Repeat	WD40 repeat	Interproscan
IPR019775 all species →	Conserved_site	WD40 repeat, conserved site	Interproscan
IPR015943 all species →	Homologous_superfamily	WD40/YVTN repeat-like-containing domain superfamily	Interproscan
IPR020472 all species →	Repeat	G-protein beta WD-40 repeat	Interproscan
IPR036322 all species →	Homologous_superfamily	WD40-repeat-containing domain superfamily	Interproscan
IPR051865 all species →	Family	WD repeat-containing CDT2 adapter protein	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR22852 all species →	LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0030674 all species →	Molecular Function	protein-macromolecule adaptor activity	Interproscan
GO:0043161 all species →	Biological Process	proteasome-mediated ubiquitin-dependent protein catabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K11790	DTL, CDT2, DCAF2; denticleless	-	Ubiquitin system	ko04121	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032241691.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

34TPM > 0

16Conditions

6.0Max TPM

1.0Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole 6 week old aboral regenerate · regenerate 96hpa	3	1	0.65	1.94
whole 6 week old aboral regenerate · regenerate 144hpa	3	3	1.33	1.58
whole 6 week old aboral regenerate · regenerate 0hpa	3	3	0.59	0.72
whole 6 week old aboral regenerate · regenerate 2hpa	3	3	1.06	1.19
whole 6 week old aboral regenerate · regenerate uncut	3	3	0.84	1.02
whole 6 week old aboral regenerate · regenerate 4hpa	3	1	0.35	1.06
whole 6 week old aboral regenerate · regenerate 120hpa	3	2	1.21	2.10
whole 6 week old aboral regenerate · regenerate 36hpa	3	3	2.11	2.19
whole 6 week old aboral regenerate · regenerate 24hpa	3	2	0.64	1.18
whole 6 week old aboral regenerate · regenerate 20hpa	3	2	0.43	0.74
whole 6 week old aboral regenerate · regenerate 16hpa	3	2	0.41	0.67
whole 6 week old aboral regenerate · regenerate 72hpa	3	2	1.48	2.40
whole 6 week old aboral regenerate · regenerate 60hpa	3	3	3.39	6.00
whole 6 week old aboral regenerate · regenerate 48hpa	3	1	0.60	1.81
whole 6 week old aboral regenerate · regenerate 8hpa	3	2	0.48	0.81
whole 6 week old aboral regenerate · regenerate 12hpa	3	1	0.28	0.85

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6320836	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	1.94
SRR6320837	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	0.00
SRR6320863	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	0.00
SRR6320847	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	1.58
SRR6320838	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	1.34
SRR6320841	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	1.06
SRR6320840	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	0.72
SRR6320839	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	0.72
SRR6320846	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	0.34
SRR6320861	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	1.19
SRR6320842	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	1.15
SRR6320848	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	0.85
SRR6320843	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	1.02
SRR6320844	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	0.88
SRR6320845	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	0.63
SRR6320872	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	1.06
SRR6320849	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	0.00
SRR6320873	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	0.00
SRR6320882	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	2.10
SRR6320883	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	1.54
SRR6320850	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	0.00
SRR6320851	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	2.19
SRR6320852	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	2.16
SRR6320855	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	1.98
SRR6320854	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	1.18
SRR6320853	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	0.73
SRR6320856	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	0.00
SRR6320857	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	0.74
SRR6320860	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	0.54
SRR6320859	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	0.00
SRR6320880	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	0.67
SRR6320858	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	0.56
SRR6320881	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	0.00
SRR6320865	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	2.40
SRR6320862	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	2.03
SRR6320864	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	0.00
SRR6320869	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	6.00
SRR6320866	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	2.41
SRR6320867	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	1.77
SRR6320870	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	1.81
SRR6320868	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320871	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320875	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.81
SRR6320874	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.63
SRR6320876	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.00
SRR6320877	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.85
SRR6320878	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00
SRR6320879	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.